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7bvt
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of cyclic alpha-maltosyl-1,6-maltose binding protein from Arthrobacter globiformis== | |
| + | <StructureSection load='7bvt' size='340' side='right'caption='[[7bvt]], [[Resolution|resolution]] 1.47Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7bvt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BVT FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bvt OCA], [https://pdbe.org/7bvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bvt RCSB], [https://www.ebi.ac.uk/pdbsum/7bvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bvt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D2YYD8_ARTGO D2YYD8_ARTGO] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Cyclic alpha-maltosyl-(1-->6)-maltose (CMM) is a cyclic glucotetrasaccharide with alternating alpha-1,4 and alpha-1,6 linkages. Here, we report functional and structural analyses on CMM-binding protein (CMMBP), which is a substrate-binding protein (SBP) of an ABC importer system of the bacteria Arthrobacter globiformis. Isothermal titration calorimetry analysis revealed that CMMBP specifically bound to CMM with a Kd value of 9.6 nM. The crystal structure of CMMBP was determined at a resolution of 1.47 A, and a panose molecule was bound in a cleft between two domains. To delineate its structural features, the crystal structure of CMMBP was compared with other SBPs specific for carbohydrates, such as cyclic alpha-nigerosyl-(1-->6)-nigerose and cyclodextrins. These results indicate that A. globiformis has a unique metabolic pathway specialized for CMM. | ||
| - | + | Molecular analysis of cyclic alpha-maltosyl-(1-->6)-maltose binding protein in the bacterial metabolic pathway.,Kohno M, Arakawa T, Sunagawa N, Mori T, Igarashi K, Nishimoto T, Fushinobu S PLoS One. 2020 Nov 19;15(11):e0241912. doi: 10.1371/journal.pone.0241912. , eCollection 2020. PMID:33211750<ref>PMID:33211750</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 7bvt" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arthrobacter globiformis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arakawa T]] | ||
| + | [[Category: Fushinobu S]] | ||
| + | [[Category: Kohno M]] | ||
| + | [[Category: Mori T]] | ||
| + | [[Category: Nishimoto T]] | ||
Current revision
Crystal structure of cyclic alpha-maltosyl-1,6-maltose binding protein from Arthrobacter globiformis
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