6waj
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the UBL domain of human NLE1== | ==Crystal structure of the UBL domain of human NLE1== | ||
| - | <StructureSection load='6waj' size='340' side='right'caption='[[6waj]]' scene=''> | + | <StructureSection load='6waj' size='340' side='right'caption='[[6waj]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WAJ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6waj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WAJ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6waj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6waj OCA], [https://pdbe.org/6waj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6waj RCSB], [https://www.ebi.ac.uk/pdbsum/6waj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6waj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NLE1_HUMAN NLE1_HUMAN] Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | [[Category: Arrowsmith CH]] | ||
Current revision
Crystal structure of the UBL domain of human NLE1
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Edwards AM | Halabelian L | Li Y | Zeng H
