5eos

<table><tr><td colspan='2'>[[5eos]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EOS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EOS FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gbi|3gbi]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5eos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eos OCA], [http://pdbe.org/5eos PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eos RCSB], [http://www.ebi.ac.uk/pdbsum/5eos PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eos ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

There is an increasing appreciation for structural diversity of DNA that is of interest to both DNA nanotechnology and basic biology. Here, we have explored how DNA responds to torsional stress by building on a previously reported two-turn DNA tensegrity triangle and demonstrating that we could introduce an extra nucleotide pair (np) into the original sequence without affecting assembly and crystallization. The extra np imposes a significant torsional stress, which is accommodated by global changes throughout the B-DNA duplex and the DNA lattice. The work reveals a near-atomic structure of naked DNA under a torsional stress of approximately 14%, and thus provides an example of DNA distortions that occur without a requirement for either an external energy source or the free energy available from protein or drug binding.

Self-Assembly of 3D DNA Crystals Containing a Torsionally Stressed Component.,Hernandez C, Birktoft JJ, Ohayon YP, Chandrasekaran AR, Abdallah H, Sha R, Stojanoff V, Mao C, Seeman NC Cell Chem Biol. 2017 Oct 5. pii: S2451-9456(17)30316-1. doi:, 10.1016/j.chembiol.2017.08.018. PMID:28988948<ref>PMID:28988948</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 5eos" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Birktoft, J J]]

[[Category: Hernandez, C]]

[[Category: Seeman, N C]]

[[Category: Dna]]

[[Category: Torsionally strained dna]]