Sandbox 30007
From Proteopedia
(Difference between revisions)
(New page: <SX viewer='molstar' load='' size='340' side='right' caption='' scene=''> {{Theoretical_model}} == Function == '''Non-structural protein 7 (nsp7)''' Forms a hexadecamer with [[SARS-CoV-2_p...) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | <SX viewer='molstar' load='' size='340' side='right' caption='' scene=''> | + | <SX viewer='molstar' load='' size='340' side='right' caption='NSP7 model from Zhang Lab (TM Score=.89)' scene='84/842938/1'> |
{{Theoretical_model}} | {{Theoretical_model}} | ||
== Function == | == Function == | ||
'''Non-structural protein 7 (nsp7)''' | '''Non-structural protein 7 (nsp7)''' | ||
| - | Forms a hexadecamer with [[SARS-CoV-2_protein_NSP8|nsp8]] (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.<ref>[ | + | Forms a hexadecamer with [[SARS-CoV-2_protein_NSP8|nsp8]] (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.<ref>[http://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref> |
== Disease == | == Disease == | ||
Current revision
| |||||||||
References
- ↑ Modeling of the SARS-COV-2 Genome
- ↑ Zhang C, Zheng W, Huang X, Bell EW, Zhou X, Zhang Y. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. J Proteome Res. 2020 Apr 3;19(4):1351-1360. doi: 10.1021/acs.jproteome.0c00129., Epub 2020 Mar 24. PMID:32200634 doi:http://dx.doi.org/10.1021/acs.jproteome.0c00129
