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6l48
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==Structure of the human sterol O-acyltransferase 1 in resting state== | ==Structure of the human sterol O-acyltransferase 1 in resting state== | ||
| - | <StructureSection load='6l48' size='340' side='right'caption='[[6l48]]' scene=''> | + | <StructureSection load='6l48' size='340' side='right'caption='[[6l48]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L48 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6l48]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L48 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l48 OCA], [https://pdbe.org/6l48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l48 RCSB], [https://www.ebi.ac.uk/pdbsum/6l48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l48 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SOAT1_HUMAN SOAT1_HUMAN] Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen L]] | [[Category: Chen L]] | ||
[[Category: Guan C]] | [[Category: Guan C]] | ||
[[Category: Niu Y]] | [[Category: Niu Y]] | ||
Current revision
Structure of the human sterol O-acyltransferase 1 in resting state
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Categories: Homo sapiens | Large Structures | Chen L | Guan C | Niu Y
