This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6me6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:29, 11 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6me6' size='340' side='right'caption='[[6me6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='6me6' size='340' side='right'caption='[[6me6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6me6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ME6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ME6 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6me6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_pasteurianum Clostridium pasteurianum], [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ME6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ME6 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JEY:N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide'>JEY</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTNR1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JEY:N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide'>JEY</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6me6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6me6 OCA], [http://pdbe.org/6me6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6me6 RCSB], [http://www.ebi.ac.uk/pdbsum/6me6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6me6 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6me6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6me6 OCA], [https://pdbe.org/6me6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6me6 RCSB], [https://www.ebi.ac.uk/pdbsum/6me6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6me6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX]] Electron-transport protein of unknown function.
+
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/MTR1B_HUMAN MTR1B_HUMAN] High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.[https://www.uniprot.org/uniprot/RUBR_CLOPA RUBR_CLOPA] Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus coli migula 1895]]
+
[[Category: Clostridium pasteurianum]]
 +
[[Category: Escherichia coli]]
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Batyuk, A]]
+
[[Category: Batyuk A]]
-
[[Category: Cherezov, V]]
+
[[Category: Cherezov V]]
-
[[Category: Gati, C]]
+
[[Category: Gati C]]
-
[[Category: Grandner, J]]
+
[[Category: Grandner J]]
-
[[Category: Han, G W]]
+
[[Category: Han GW]]
-
[[Category: Hao, S]]
+
[[Category: Hao S]]
-
[[Category: Johansson, L C]]
+
[[Category: Johansson LC]]
-
[[Category: Katritch, V]]
+
[[Category: Katritch V]]
-
[[Category: Li, C]]
+
[[Category: Li C]]
-
[[Category: Liu, W]]
+
[[Category: Liu W]]
-
[[Category: McCorvy, J]]
+
[[Category: McCorvy J]]
-
[[Category: Olsen, R H.J]]
+
[[Category: Olsen RHJ]]
-
[[Category: Patel, N]]
+
[[Category: Patel N]]
-
[[Category: Roth, B L]]
+
[[Category: Roth BL]]
-
[[Category: Stauch, B]]
+
[[Category: Stauch B]]
-
[[Category: Tribo, A R]]
+
[[Category: Tribo AR]]
-
[[Category: Weierstall, U]]
+
[[Category: Weierstall U]]
-
[[Category: Zaare, S]]
+
[[Category: Zaare S]]
-
[[Category: Zatsepin, N A]]
+
[[Category: Zatsepin NA]]
-
[[Category: Zhu, L]]
+
[[Category: Zhu L]]
-
[[Category: 2-phenylmelatonin]]
+
-
[[Category: Bril]]
+
-
[[Category: Circadian rhythm]]
+
-
[[Category: Gpcr]]
+
-
[[Category: Jetlag]]
+
-
[[Category: Lcp]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Rubredoxin]]
+
-
[[Category: Type 2 diabetes]]
+
-
[[Category: Xfel]]
+

Current revision

XFEL crystal structure of human melatonin receptor MT2 in complex with 2-phenylmelatonin

PDB ID 6me6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6me6"
Personal tools