6txz

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Current revision (13:12, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6txz' size='340' side='right'caption='[[6txz]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
<StructureSection load='6txz' size='340' side='right'caption='[[6txz]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6txz]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TXZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TXZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6txz]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TXZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TXZ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HAVCR2, TIM3, TIMD3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.06&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6txz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6txz OCA], [http://pdbe.org/6txz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6txz RCSB], [http://www.ebi.ac.uk/pdbsum/6txz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6txz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6txz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6txz OCA], [https://pdbe.org/6txz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6txz RCSB], [https://www.ebi.ac.uk/pdbsum/6txz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6txz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN]] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref>
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[https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6txz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6txz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Musil, D]]
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[[Category: Musil D]]
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[[Category: Sood, V]]
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[[Category: Sood V]]
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[[Category: Antibody]]
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[[Category: Fab]]
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[[Category: Immune system]]
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[[Category: Tim3]]
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Current revision

FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3

PDB ID 6txz

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