7bu5

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'''Unreleased structure'''
 
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The entry 7bu5 is ON HOLD until Paper Publication
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==Crystal Structure of Human SLX4 and MUS81==
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<StructureSection load='7bu5' size='340' side='right'caption='[[7bu5]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors: Wan, B., Wu, J., Lei, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7bu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BU5 FirstGlance]. <br>
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Description: Crystal Structure of Human SLX4 and MUS81
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
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[[Category: Wu, J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bu5 OCA], [https://pdbe.org/7bu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bu5 RCSB], [https://www.ebi.ac.uk/pdbsum/7bu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bu5 ProSAT]</span></td></tr>
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[[Category: Lei, M]]
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</table>
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[[Category: Wan, B]]
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== Function ==
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[https://www.uniprot.org/uniprot/MUS81_HUMAN MUS81_HUMAN] Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.<ref>PMID:11741546</ref> <ref>PMID:12374758</ref> <ref>PMID:12686547</ref> <ref>PMID:12721304</ref> <ref>PMID:14617801</ref> <ref>PMID:15805243</ref> <ref>PMID:17289582</ref> <ref>PMID:19595721</ref> <ref>PMID:19596235</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Lei M]]
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[[Category: Wan B]]
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[[Category: Wu J]]

Current revision

Crystal Structure of Human SLX4 and MUS81

PDB ID 7bu5

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