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6kdv

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Current revision (12:48, 6 November 2024) (edit) (undo)
 
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<StructureSection load='6kdv' size='340' side='right'caption='[[6kdv]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
<StructureSection load='6kdv' size='340' side='right'caption='[[6kdv]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6kdv]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KDV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6KDV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6kdv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KDV FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cas1-2, TTHB193 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6kdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kdv OCA], [http://pdbe.org/6kdv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kdv RCSB], [http://www.ebi.ac.uk/pdbsum/6kdv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kdv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kdv OCA], [https://pdbe.org/6kdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kdv RCSB], [https://www.ebi.ac.uk/pdbsum/6kdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kdv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CAS1B_THET8 CAS1B_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
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[https://www.uniprot.org/uniprot/CAS1B_THET8 CAS1B_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6kdv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6kdv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Synthetic construct]]
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[[Category: Li, J Z]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Wang, J Y]]
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[[Category: Li JZ]]
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[[Category: Wang, Y L]]
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[[Category: Wang JY]]
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[[Category: Yang, J]]
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[[Category: Wang YL]]
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[[Category: Cas1]]
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[[Category: Yang J]]
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[[Category: Crispr]]
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[[Category: Dna binding protein]]
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[[Category: Dna binding protein-dna complex]]
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Current revision

Crystal structure of TtCas1-DNA complex

PDB ID 6kdv

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