2lbu
From Proteopedia
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==HADDOCK calculated model of Congo red bound to the HET-s amyloid== | ==HADDOCK calculated model of Congo red bound to the HET-s amyloid== | ||
| - | <StructureSection load='2lbu' size='340' side='right'caption='[[2lbu | + | <StructureSection load='2lbu' size='340' side='right'caption='[[2lbu]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lbu]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lbu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Podospora_anserina Podospora anserina]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBU FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGO:SODIUM+3,3-(1E,1E)-BIPHENYL-4,4-DIYLBIS(DIAZENE-2,1-DIYL)BIS(4-AMINONAPHTHALENE-1-SULFONATE)'>CGO</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR, 4 models</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGO:SODIUM+3,3-(1E,1E)-BIPHENYL-4,4-DIYLBIS(DIAZENE-2,1-DIYL)BIS(4-AMINONAPHTHALENE-1-SULFONATE)'>CGO</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbu OCA], [https://pdbe.org/2lbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbu RCSB], [https://www.ebi.ac.uk/pdbsum/2lbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbu ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HETS_PODAS HETS_PODAS] Responsible for heterokaryon incompatibility, a process that ensures that during spontaneous, vegetative cell fusion only compatible cells from the same colony survive (non-self-recognition). Forms a prion for the non-Mendelian trait [het-s]. Interacts with het-S from incompatible cells to trigger a lethal reaction that prevents the formation of viable heterokaryons. It is unknown if the native, soluble protein has a cellular function.<ref>PMID:1886611</ref> <ref>PMID:8224826</ref> <ref>PMID:9275200</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Podospora anserina]] |
| - | [[Category: Aguzzi | + | [[Category: Aguzzi A]] |
| - | [[Category: Bockmann | + | [[Category: Bockmann A]] |
| - | [[Category: Ernst | + | [[Category: Ernst M]] |
| - | [[Category: Hornemann | + | [[Category: Hornemann S]] |
| - | [[Category: Meier | + | [[Category: Meier BH]] |
| - | [[Category: Schutz | + | [[Category: Schutz AK]] |
| - | [[Category: Soragni | + | [[Category: Soragni A]] |
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Current revision
HADDOCK calculated model of Congo red bound to the HET-s amyloid
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