6vrc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Cas13(crRNA)== | |
| - | + | <StructureSection load='6vrc' size='340' side='right'caption='[[6vrc]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6vrc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_seeligeri_serovar_1/2b_str._SLCC3954 Listeria seeligeri serovar 1/2b str. SLCC3954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VRC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vrc OCA], [https://pdbe.org/6vrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vrc RCSB], [https://www.ebi.ac.uk/pdbsum/6vrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vrc ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CS13A_LISSS CS13A_LISSS] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. Unlike many single-component effectors, this CRISPR-Cas system targets RNA (By similarity). CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:27669025).[UniProtKB:P0DOC6]<ref>PMID:27669025</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Listeria seeligeri serovar 1/2b str. SLCC3954]] | ||
| + | [[Category: Jia N]] | ||
| + | [[Category: Marraffini LA]] | ||
| + | [[Category: Meeske AJ]] | ||
| + | [[Category: Patel DJ]] | ||
Current revision
Cryo-EM structure of Cas13(crRNA)
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