6wtp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6wtp is ON HOLD Authors: Yu, S., Nithianantham, S., Fischer, M. Description: Crystal Structure of Janus Kinase 2 in complex with a baricitinib base...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 3== | |
| + | <StructureSection load='6wtp' size='340' side='right'caption='[[6wtp]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WTP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=U8P:tert-butyl+4-[(4-{1-[3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl}-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino]benzoate'>U8P</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wtp OCA], [https://pdbe.org/6wtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wtp RCSB], [https://www.ebi.ac.uk/pdbsum/6wtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wtp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Janus kinase 3D structures|Janus kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fischer M]] |
| - | [[Category: | + | [[Category: Nithianantham S]] |
| + | [[Category: Yu S]] | ||
Current revision
Human JAK2 JH1 domain in complex with PROTAC-intermediate linker handle 3
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