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6s4m
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==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ||
| - | <StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]]' scene=''> | + | <StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | [[Category: Arrowsmith CH]] | ||
Current revision
Crystal structure of the human organic anion transporter MFSD10 (TETRAN)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown NA | Bushell SR | Carpenter EP | Chalk R | Chu A | Edwards AM | Mukhopadhyay SMM | Pascoa TC | Pike ACW | Quigley A | Shrestha L | Venkaya S
