2mb3

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==Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative==
==Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative==
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<StructureSection load='2mb3' size='340' side='right'caption='[[2mb3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2mb3' size='340' side='right'caption='[[2mb3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mb3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MB3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MB3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mb3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MB3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L2H:(12S,27S)-12,27-BIS(4-AMINOBUTYL)-4,30-DIMETHYL-3,7,14,18,22,29-HEXAOXA-11,26,31,32,33,34,35,36-OCTAAZAHEPTACYCLO[26.2.1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]HEXATRIACONTA-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-DODECAENE-10,25-DIONE'>L2H</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mb3 OCA], [http://pdbe.org/2mb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mb3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mb3 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L2H:(12S,27S)-12,27-BIS(4-AMINOBUTYL)-4,30-DIMETHYL-3,7,14,18,22,29-HEXAOXA-11,26,31,32,33,34,35,36-OCTAAZAHEPTACYCLO[26.2.1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]HEXATRIACONTA-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-DODECAENE-10,25-DIONE'>L2H</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mb3 OCA], [https://pdbe.org/2mb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mb3 RCSB], [https://www.ebi.ac.uk/pdbsum/2mb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mb3 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chung, W J]]
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[[Category: Chung WJ]]
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[[Category: Heddi, B]]
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[[Category: Heddi B]]
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[[Category: Iida, K]]
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[[Category: Iida K]]
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[[Category: Nagasawa, K]]
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[[Category: Nagasawa K]]
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[[Category: Phan, A T]]
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[[Category: Phan AT]]
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[[Category: Tera, M]]
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[[Category: Tera M]]
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[[Category: Anticancer target]]
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[[Category: Dna-dna inhibitor complex]]
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[[Category: Human telomere]]
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[[Category: Intramolecular g-quadruplex]]
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[[Category: Macrocyclic hexaoxazole]]
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[[Category: Telomestatin derivative]]
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Current revision

Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative

PDB ID 2mb3

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