This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6wsm
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of coiled coil region of human septin 8== | |
| - | + | <StructureSection load='6wsm' size='340' side='right'caption='[[6wsm]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6wsm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WSM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.451Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wsm OCA], [https://pdbe.org/6wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wsm RCSB], [https://www.ebi.ac.uk/pdbsum/6wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wsm ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/SEPT8_HUMAN SEPT8_HUMAN] Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (PubMed:15116257). Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).[UniProtKB:B0BNF1]<ref>PMID:15116257</ref> Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP.<ref>PMID:27084579</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: Garratt | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Uson | + | [[Category: Large Structures]] |
| + | [[Category: Araujo APU]] | ||
| + | [[Category: Brandao-Neto J]] | ||
| + | [[Category: Cabrejos DAL]] | ||
| + | [[Category: Cavini I]] | ||
| + | [[Category: Garratt RC]] | ||
| + | [[Category: Nascimento AFZ]] | ||
| + | [[Category: Pereira HM]] | ||
| + | [[Category: Sala FA]] | ||
| + | [[Category: Uson I]] | ||
| + | [[Category: Valadares NF]] | ||
Current revision
Crystal structure of coiled coil region of human septin 8
| |||||||||||
