6wsm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of coiled coil region of human septin 8== | |
| - | + | <StructureSection load='6wsm' size='340' side='right'caption='[[6wsm]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6wsm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WSM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.451Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wsm OCA], [https://pdbe.org/6wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wsm RCSB], [https://www.ebi.ac.uk/pdbsum/6wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wsm ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/SEPT8_HUMAN SEPT8_HUMAN] Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion (PubMed:15116257). Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).[UniProtKB:B0BNF1]<ref>PMID:15116257</ref> Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP.<ref>PMID:27084579</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: Garratt | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Uson | + | [[Category: Large Structures]] |
| + | [[Category: Araujo APU]] | ||
| + | [[Category: Brandao-Neto J]] | ||
| + | [[Category: Cabrejos DAL]] | ||
| + | [[Category: Cavini I]] | ||
| + | [[Category: Garratt RC]] | ||
| + | [[Category: Nascimento AFZ]] | ||
| + | [[Category: Pereira HM]] | ||
| + | [[Category: Sala FA]] | ||
| + | [[Category: Uson I]] | ||
| + | [[Category: Valadares NF]] | ||
Current revision
Crystal structure of coiled coil region of human septin 8
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