6z1q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6z1q is ON HOLD Authors: Jacoby, E., van Vlijmen, H., Querolle, O., Stansfield, I., Meerpoel, L., Versele, M., Hynd, G., Attar, R. Description: MAP...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==MAP3K14 (NIK) in complex with DesF-3R/4076== | |
| + | <StructureSection load='6z1q' size='340' side='right'caption='[[6z1q]], [[Resolution|resolution]] 2.42Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6z1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z1Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Q58:DesF-3R/4076'>Q58</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1q OCA], [https://pdbe.org/6z1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z1q RCSB], [https://www.ebi.ac.uk/pdbsum/6z1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/M3K14_HUMAN M3K14_HUMAN] Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.<ref>PMID:15084608</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Mitogen-activated protein kinase kinase kinase|Mitogen-activated protein kinase kinase kinase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Attar R]] |
| - | [[Category: | + | [[Category: Hynd G]] |
| - | [[Category: | + | [[Category: Jacoby E]] |
| - | [[Category: | + | [[Category: Meerpoel L]] |
| + | [[Category: Querolle O]] | ||
| + | [[Category: Stansfield I]] | ||
| + | [[Category: Versele M]] | ||
| + | [[Category: Van Vlijmen H]] | ||
Current revision
MAP3K14 (NIK) in complex with DesF-3R/4076
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Categories: Homo sapiens | Large Structures | Attar R | Hynd G | Jacoby E | Meerpoel L | Querolle O | Stansfield I | Versele M | Van Vlijmen H
