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6z1t

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'''Unreleased structure'''
 
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The entry 6z1t is ON HOLD
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==MAP3K14 (NIK) in complex with 4S/3694==
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<StructureSection load='6z1t' size='340' side='right'caption='[[6z1t]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6z1t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z1T FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Q55:4S/3694'>Q55</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z1t OCA], [https://pdbe.org/6z1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z1t RCSB], [https://www.ebi.ac.uk/pdbsum/6z1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z1t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/M3K14_HUMAN M3K14_HUMAN] Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.<ref>PMID:15084608</ref>
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Authors: Jacoby, E., van Vlijmen, H., Querolle, O., Stansfield, I., Meerpoel, L., Versele, M., Hynd, G., Attar, R.
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==See Also==
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*[[Mitogen-activated protein kinase kinase kinase|Mitogen-activated protein kinase kinase kinase]]
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Description: MAP3K14 (NIK) in complex with 4S/3694
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Querolle, O]]
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__TOC__
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[[Category: Versele, M]]
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</StructureSection>
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[[Category: Stansfield, I]]
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[[Category: Homo sapiens]]
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[[Category: Van Vlijmen, H]]
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[[Category: Large Structures]]
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[[Category: Attar, R]]
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[[Category: Attar R]]
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[[Category: Hynd, G]]
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[[Category: Hynd G]]
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[[Category: Meerpoel, L]]
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[[Category: Jacoby E]]
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[[Category: Jacoby, E]]
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[[Category: Meerpoel L]]
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[[Category: Querolle O]]
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[[Category: Stansfield I]]
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[[Category: Versele M]]
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[[Category: Van Vlijmen H]]

Current revision

MAP3K14 (NIK) in complex with 4S/3694

PDB ID 6z1t

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