6sgr

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<StructureSection load='6sgr' size='340' side='right'caption='[[6sgr]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
<StructureSection load='6sgr' size='340' side='right'caption='[[6sgr]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6sgr]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SGR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6SGR FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SGR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SGR FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6sgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sgr OCA], [http://pdbe.org/6sgr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sgr RCSB], [http://www.ebi.ac.uk/pdbsum/6sgr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sgr ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.17&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sgr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sgr OCA], [https://pdbe.org/6sgr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sgr RCSB], [https://www.ebi.ac.uk/pdbsum/6sgr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sgr ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> [[http://www.uniprot.org/uniprot/ACRZ_ECOLI ACRZ_ECOLI]] AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.<ref>PMID:23010927</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Du, D]]
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[[Category: Du D]]
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[[Category: Luisi, B F]]
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[[Category: Luisi BF]]
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[[Category: Neuberger, A]]
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[[Category: Neuberger A]]
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[[Category: Newman, C]]
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[[Category: Newman C]]
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[[Category: Szewczak-Harris, A]]
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[[Category: Szewczak-Harris A]]
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[[Category: Antibiotic resistance]]
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[[Category: Drug transport]]
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[[Category: Efflux pump]]
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[[Category: Lipid nanodisc]]
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[[Category: Membrane protein]]
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[[Category: Rnd transporter]]
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Current revision

Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin

PDB ID 6sgr

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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