2nu2

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<StructureSection load='2nu2' size='340' side='right'caption='[[2nu2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2nu2' size='340' side='right'caption='[[2nu2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nu2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga] and [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2NU2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nu2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU2 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sgb|3sgb]], [[2nu0|2nu0]], [[2nu1|2nu1]], [[2nu3|2nu3]], [[2nu4|2nu4]], [[4sga|4sga]], [[1mct|1mct]], [[1hja|1hja]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Streptogrisin_B Streptogrisin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.81 3.4.21.81] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu2 OCA], [https://pdbe.org/2nu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu2 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2nu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu2 OCA], [http://pdbe.org/2nu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nu2 RCSB], [http://www.ebi.ac.uk/pdbsum/2nu2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR]] Has a primary specificity for large aliphatic or aromatic amino acids.
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[https://www.uniprot.org/uniprot/IOVO_MELGA IOVO_MELGA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu2_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Melga]]
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[[Category: Meleagris gallopavo]]
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[[Category: Streptogrisin B]]
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[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
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[[Category: Anderson, S]]
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[[Category: Anderson S]]
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[[Category: Bateman, K S]]
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[[Category: Bateman KS]]
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[[Category: James, M N.G]]
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[[Category: James MNG]]
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[[Category: Laskowski, M]]
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[[Category: Laskowski Jr M]]
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[[Category: Lu, W]]
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[[Category: Lu W]]
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[[Category: Qasim, M A]]
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[[Category: Qasim MA]]
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[[Category: Charged p1 residue]]
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[[Category: Enzyme-inhibitor complex]]
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[[Category: Hydrolase]]
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Current revision

Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I

PDB ID 2nu2

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