HPPK 3D structures
From Proteopedia
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==3D structures of [[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]]== | ==3D structures of [[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]]== | ||
- | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase]] |
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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**[[1g4c]], [[1im6]], [[1kbr]], [[1rtz]], [[1tmj]], [[3hcx]], [[3hsd]], [[3hsj]], [[3hsz]], [[3ili]], [[3ill]], [[3kue]], [[3kug]] – EcHPPK (mutant) <br /> | **[[1g4c]], [[1im6]], [[1kbr]], [[1rtz]], [[1tmj]], [[3hcx]], [[3hsd]], [[3hsj]], [[3hsz]], [[3ili]], [[3ill]], [[3kue]], [[3kug]] – EcHPPK (mutant) <br /> | ||
**[[2f63]], [[2f65]] – EcHPPK - NMR <br /> | **[[2f63]], [[2f65]] – EcHPPK - NMR <br /> | ||
+ | **[[8sd5]] – MjHPPK – ''Methanocaldococcus jannaschii''<br /> | ||
*HPPK binary complex | *HPPK binary complex | ||
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**[[1rb0]] – EcHPPK + 6-hydroxymethylpterin-diphosphate <br /> | **[[1rb0]] – EcHPPK + 6-hydroxymethylpterin-diphosphate <br /> | ||
**[[3hd1]], [[3hsg]], [[3ht0]], [[3ilj]], [[3kuh]] – EcHPPK (mutant) + methyleneadenosine-triphosphate <br /> | **[[3hd1]], [[3hsg]], [[3ht0]], [[3ilj]], [[3kuh]] – EcHPPK (mutant) + methyleneadenosine-triphosphate <br /> | ||
- | **[[3ud5]], [[3ude]], [[3udv]], [[4f7v]], [[6an4]], [[6an6]] – EcHPPK + inhibitor <br /> | + | **[[3ud5]], [[3ude]], [[3udv]], [[4f7v]], [[6an4]], [[6an6]], [[7kdo]], [[7kdr]], [[8sif]] – EcHPPK + inhibitor <br /> |
**[[4pzv]] - HPPK/DHPS + inhibitor - ''Francisella tularensis''<br /> | **[[4pzv]] - HPPK/DHPS + inhibitor - ''Francisella tularensis''<br /> | ||
**[[3qbc]] – SaHPPK + inhibitor – ''Staphylococcus aureus''<br /> | **[[3qbc]] – SaHPPK + inhibitor – ''Staphylococcus aureus''<br /> | ||
+ | **[[8sk1]] – HPPK + inhibitor – ''Bacillus anthracis''<br /> | ||
+ | **[[8sbu]] – MjHPPK/MBP<br /> | ||
+ | |||
*HPPK ternary complex | *HPPK ternary complex | ||
- | **[[1ru2]], [[1tmm]] – EcHPPK (mutant) + | + | **[[1ru2]], [[1tmm]] – EcHPPK (mutant) + ATP derivative + 6-hydroxymethylpterin <br /> |
**[[1dy3]] – EcHPPK (mutant) + ATP + pteridine derivative <br /> | **[[1dy3]] – EcHPPK (mutant) + ATP + pteridine derivative <br /> | ||
- | **[[3ip0]] – EcHPPK + | + | **[[3ip0]] – EcHPPK + ATP derivative + pteridine derivative <br /> |
- | **[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + | + | **[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + ATP derivative + pteridine derivative <br /> |
- | **[[3hd2]] – EcHPPK (mutant) + | + | **[[3hd2]] – EcHPPK (mutant) + ATP derivative + pterine <br /> |
- | **[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + | + | **[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + ATP derivative + inhibitor <br /> |
**[[1rao]] – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate <br /> | **[[1rao]] – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate <br /> | ||
**[[5etl]], [[5etm]], [[5etn]], [[5eto]], [[5etp]], [[5etq]], [[5etr]], [[5ets]], [[5ett]], [[5etv]] - EcHPPK + AMPCPP + inhibitor<br /> | **[[5etl]], [[5etm]], [[5etn]], [[5eto]], [[5etp]], [[5etq]], [[5etr]], [[5ets]], [[5ett]], [[5etv]] - EcHPPK + AMPCPP + inhibitor<br /> | ||
**[[4crj]], [[4cwb]], [[4cyu]] - SaHPPK + AMPCPP + inhibitor<br /> | **[[4crj]], [[4cwb]], [[4cyu]] - SaHPPK + AMPCPP + inhibitor<br /> | ||
- | **[[2qx0]] – HPPK + | + | **[[2qx0]] – HPPK + ATP derivative, [[5etk]], [[5etl]], [[5etm]], [[5etn]], [[5eto]], [[5etp]], [[5etq]], [[5etr]], [[5ets]], [[5ett]], [[5etv]] + pteridine derivative – ''Yersinia pestis''<br /> |
+ | |||
+ | *HPPK-DHPS | ||
+ | |||
+ | **[[7mpy]] – HPPK-DHPS – ''Arabidopsis thaliana''<br /> | ||
+ | **[[5z79]] – HPPK-DHPS + ATP derivative + pteridine derivative + pterine + adenosine derivative + 4-aminobenzoic acid – ''Plasmodium vivax''<br /> | ||
+ | **[[3mcm]] – FtHPPK-DHPS – ''Francisella tularensis''<br /> | ||
+ | **[[3mcn]], [[8sl9]] – FtHPPK-DHPS + inhibitor <br /> | ||
+ | **[[4pzv]] – FtHPPK-DHPS + bisubstrate inhibitor <br /> | ||
+ | **[[3mco]] – FtHPPK-DHPS + ATP derivative<br /> | ||
+ | **[[6jwu]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum'' <br /> | ||
+ | **[[6jwq]] – PfHPPK-DHPS + ATP + AMP <br /> | ||
+ | **[[6jws]], [[6jwt]] – PfHPPK-DHPS (mutant) + ATP + pteroate <br /> | ||
+ | **[[6jwr]] – PfHPPK-DHPS (mutant) + AMP + pteroate <br /> | ||
+ | **[[6jwz]] – PfHPPK-DHPS (mutant) + AMP + pteridine derivative <br /> | ||
+ | **[[6jwv]], [[6jwy]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative <br /> | ||
+ | **[[6jww]] – PfHPPK-DHPS (mutant) + ATP + AMP + pteridine derivative <br /> | ||
+ | **[[6kck]] – PfHPPK-DHPS + ATP derivative + pterine + hydroxybenzoate<br /> | ||
+ | **[[6kcl]], [[6kcm]] – PfHPPK-DHPS (mutant) + ATP derivative + pterine + hydroxybenzoate<br /> | ||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Current revision
3D structures of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
Updated on 28-August-2024 - For a general description of the protein see 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase