This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Antibody 3D structures
From Proteopedia
(Difference between revisions)
| (32 intermediate revisions not shown.) | |||
| Line 10: | Line 10: | ||
| - | * | + | *Fab |
| - | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]] - hFab - human<br /> | + | **[[7fab]], [[1mco]], [[3na9]], [[3lrs]], [[3mme]], [[3hi5]], [[1vge]], [[3nfs]], [[1ad0]], [[3w9d]], [[4nm4]], [[8fab]], [[1opg]], [[4fnl]], [[4fqh]], [[6n32]], [[1aqk]], [[2hff]], [[2agj]], [[3hc0]], [[3g6a]], [[3dgg]], [[3dif]], [[1b2w]], [[3eyo]], [[3eyq]], [[2aj3]], [[3fzu]], [[3aaz]], [[3gje]], [[5fhb]], [[5fha]], [[5f6i]], [[5f6h]], [[5drw]], [[5d6c]], [[4py7]], [[4ptt]], [[4ob5]], [[5szf]], [[5chn]], [[4lkc]], [[4hie]], [[4gxv]], [[6be2]], [[6be4]], [[6cbj]], [[6dcv]], [[6dwc]], [[6foe]], [[6ghg]], [[6hkg]], [[6ias]], [[7uen]], [[7uel]], [[7uem]], [[6obz]], [[6pzg]], [[6pzh]], [[6q19]], [[6q1a]], [[6q1e]], [[6q1g]], [[6q1j]], [[6q1k]], [[6qbc]], [[6qcu]], [[6u85]], [[6u9u]], [[6vi2]], [[6vrq]], [[6v4r]], [[6vpy]], [[6vtu]], [[6w5a]], [[6w5d]], [[6wiy]], [[6wj0]], [[6wla]], [[6xrj]], [[6z3k]], [[7aj6]], [[7arn]], [[7jkb]], [[7jz1]], [[7jz4]], [[7ke1]], [[7kfg]], [[7kgu]], [[7kx4]], [[7lud]], [[7lyv]], [[7lyw]], [[7m1c]], [[7mf7]], [[7mf8]], [[7mf9]], [[7mfa]], [[7n04]], [[7n07]], [[7oo2]], [[7ps3]], [[7qxc]], [[7qxd]], [[7qxe]], [[7re9]], [[7sen]], [[7tus]], [[7u04]], [[7u0k]], [[7vsu]], [[7vsw]], [[7y0g]] - hFab - human<br /> |
| - | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]] - hFab (mutant)<br /> | + | **[[3naa]], [[3nab]], [[3nac]], [[3ncj]], [[3o2v]], [[3hc3]], [[3hc4]], [[6uum]], [[6y1k]], [[6y1l]], [[6y1m]], [[6y1n]], [[7mfb]], [[7s8g]] - hFab (mutant)<br /> |
| - | **[[ | + | **[[6b6z]], [[6dzn]], [[5vz1]], [[7rpt]] - hFab anti-ebola virus<br /> |
| - | **[[ | + | **[[6mtx]], [[6mty]], [[6nis]] - hFab anti-zika virus<br /> |
| - | **[[ | + | **[[6ws6]] - hFab anti-sarbecovirus<br /> |
| - | + | **[[6phg]], [[6phh]] - hFab anti-malaria<br /> | |
| - | **[[ | + | **[[6dl8]] - hFab anti-influenza<br /> |
| + | **[[7kba]] - hFab anti-HCMV<br /> | ||
| + | **[[3i75]], [[1f4w]], [[1aif]], [[1ghf]], [[2z91]], [[1ind]], [[3bkc]], [[3bkm]], [[1iy0]], [[3pp3]], [[3pp4]], [[3okm]], [[2hkh]], [[1ay1]], [[1nbv]], [[1qbm]], [[1bbd]], [[1dsf]], [[1gpo]], [[1mnu]], [[1igf]], [[1for]], [[1k6q]], [[1bz7]], [[1dqd]], [[2ipt]], [[2iq9]], [[2iqa]], [[2w60]], [[2w9d]], [[3iu4]], [[1q9k]], [[1q9l]], [[1q9o]], [[2z4q]], [[1cl7]], [[1cr9]], [[1r24]], [[1gig]], [[1uyw]], [[1cgs]], [[2cgr]], [[1q0x]], [[1ibg]], [[3eo0]], [[2op4]], [[2q76]], [[2ojz]], [[2g60]], [[2dbl]], [[1dbj]], [[1dbk]], [[1dbm]], [[1dba]], [[1mrc]], [[2gcy]], [[1flr]], [[1uz6]], [[1rfd]], [[1t2q]], [[1ggb]], [[1ggc]], [[1bm3]], [[2eh7]], [[2fat]], [[3cfc]], [[1fl3]], [[3cfe]], [[4j1u]], [[4gq9]], [[3qg7]], [[3rvt]], [[3s62]], [[4gay]], [[5mx3]], [[5l88]], [[5i66]], [[5cma]], [[5az2]], [[4z0b]], [[4qth]], [[5vzr]], [[5lgh]], [[5l9d]], [[5l7x]], [[4lci]], [[4k23]], [[6hgu]], [[6ks2]], [[6p79]], [[6qnk]], [[6shg]], [[6ug7]], [[6ug8]], [[6uga]], [[6ugd]], [[6vl8]], [[6vl9]], [[6w4v]], [[6x5e]], [[6xuk]], [[6z7x]], [[7bg1]], [[7c95]], [[7f2s]], [[7fgk]], [[7nx2]], [[7sd2]], [[7t0f]], [[7t0g]], [[7t0h]], [[7t0k]], [[7t0i]], [[7t0j]], [[7te4]], [[7tuh]], [[7v3q]] - mFab – mouse<br /> | ||
**[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | **[[3eot]], [[2d03]], [[3esv]], [[3et9]] – mFab (mutant)<br /> | ||
**[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | **[[3iy2]], [[3iy3]], [[3iy4]], [[3iy5]], [[3iy6]], [[3iy7]] - mFab – Cryo EM<br /> | ||
| - | **[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]], [[4kuz]] - hmFab <br /> | + | **[[1jpt]], [[3mxv]], [[2o5x]], [[1ucb]], [[1bbj]], [[1t04]], [[2fgw]], [[1fvd]], [[1fve]], [[4kuz]], [[6l8t]], [[6w4w]] - hmFab <br /> |
**[[1cqk]] – mFab MAK33 CH3 domain<br /> | **[[1cqk]] – mFab MAK33 CH3 domain<br /> | ||
**[[6a0x]] - mFab anti-influenza virus<br /> | **[[6a0x]] - mFab anti-influenza virus<br /> | ||
| + | **[[6h3h]] - mFab anti-fullerene<br /> | ||
| + | **[[6pyc]] - mFab anti-kappa<br /> | ||
| + | **[[6idh]], [[6kdh]] - mFab anti-photoproduct<br /> | ||
| + | **[[6qu9]] - mFab anti-antitrypsin<br /> | ||
**[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | **[[3mj8]], [[3r06]] – AhFab – Armenian hamster<br /> | ||
**[[3iy1]], [[1zan]] – raFab – rat<br /> | **[[3iy1]], [[1zan]] – raFab – rat<br /> | ||
| - | **[[4k3e]], [[4k3d]] – bFab – bovine<br /> | + | **[[4k3e]], [[4k3d]], [[6oo0]], [[6qn7]], [[6qn8]], [[6qn9]], [[6qna]] – bFab – bovine<br /> |
| - | **[[4b41]], [[4m3j]] – LgFab – ''Lama glama''<br /> | + | **[[4b41]], [[4m3j]], [[7bnp]], [[7bnw]], [[7np9]], [[7phs]] – LgFab – ''Lama glama''<br /> |
| + | **[[6cjk]], [[7d9z]] – rFab - rabbit<br /> | ||
**[[6df0]], [[6dez]] - syFab anti-phosphotyrosine - synthetic<br /> | **[[6df0]], [[6dez]] - syFab anti-phosphotyrosine - synthetic<br /> | ||
| + | *Anti-HIV Fab or broadly neutralizing Fab | ||
| - | + | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4rqq]], [[5uy3]], [[4qf1]], [[6avn]], [[6b3d]], [[6bla]], [[6cxl]], [[6mtr]], [[6mts]], [[6o3d]], [[6o3k]], [[6uul]], [[6vu2]], [[6wor]], [[6wos]], [[7l77]], [[7l79]], [[7rdj]], [[7rdk]], [[7rdl]], [[7rdm]], [[7u0b]], [[7u0c]], [[7uce]] - hFab <br /> | |
| - | + | ||
| - | **[[1rz7]], [[1rz8]], [[1rzf]], [[1rzg]], [[1rzi]], [[3mlj]], [[3mug]], [[3qeh]], [[3ttn]], [[rpi]], [[3tnm]], [[4fz8]], [[4f58]], [[4f57]], [[4f5a]], [[5iie]], [[5dt1]], [[5cey]], [[5cex]], [[5cck]], [[5bzw]], [[5bzd]], [[4rqq]], [[5uy3]], [[4qf1]] - hFab <br /> | + | |
**[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | **[[3nz8]], [[3o6k]], [[3ntc]], [[3qeg]] – mFab <br /> | ||
**[[5kg9]] – hmFab <br /> | **[[5kg9]] – hmFab <br /> | ||
| - | **[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]], [[5t4z]] – rmFab – rhesus macaque <br /> | + | **[[5dd6]], [[5dd5]], [[5dd3]], [[5dd1]], [[4rfe]], [[4q2z]], [[5t4z]], [[6u3z]], [[6u6m]], [[6u6o]], [[6vor]], [[6vsr]], [[7ryu]], [[7ryv]] – rmFab – rhesus macaque <br /> |
| + | **[[7l6m]] – rmFab – Cryo EM <br /> | ||
| + | **[[7ra7]] – rFab <br /> | ||
| + | **[[3juy]], [[4ut7]] – hscFv anti-HIV<br /> | ||
| + | **[[3r0m]] – LgVHH anti-HIV<br /> | ||
| + | **[[2xxc]] – ViVHH anti-HIV - vicugna<br /> | ||
| + | |||
| + | *Anti-SARS-CoV-2 Fab | ||
| + | |||
| + | **[[6nb8]], [[6w7y]], [[6xca]], [[7dpm]], [[7jmx]], [[7k8n]], [[7k8o]], [[7k8p]], [[7k8q]], [[7k8r]], [[7kn3]], [[7kza]], [[7kzc]], [[7lk9]], [[7lka]], [[7n3e]], [[7n3f]], [[7n3g]], [[7n3h]], [[7sn1]], [[7wpv]], [[7zf6]], [[7zff]] - hFab anti-SARS-CoV-2<br /> | ||
| + | **[[6c6z]], [[4xak]], [[6w41]], [[6xc2]], [[6xc3]], [[6xc4]], [[6xc7]], [[6xkp]], [[6xkq]], [[6yla]], [[6zer]], [[6zlr]], [[7b3o]], [[7beh]], [[7bei]], [[7bej]], [[7bek]], [[7bel]], [[7bem]], [[7ben]], [[7beo]], [[7bep]], [[7bnv]], [[7bwj]], [[7bz5]], [[7c01]], [[7cah]], [[7cdi]], [[7cdj]], [[7ch4]], [[7ch5]], [[7chb]], [[7chc]], [[7che]], [[7chf]], [[7cho]], [[7chp]], [[7chs]], [[7cjf]], [[7cm4]], [[7djz]], [[7dk0]], [[7dk2]], [[7e3o]], [[7e5o]], [[7e5y]], [[7e7x]], [[7e7y]], [[7e86]], [[7e88]], [[7e8m]], [[7ejy]], [[7ejz]], [[7f6y]], [[7f7e]], [[7f7h]], [[7fcp]], [[7fcq]], [[7fjc]], [[7jjs]], [[7jmo]], [[7jmp]], [[7jmw]], [[7jn5]], [[7jx3]], [[7k8m]], [[7k9z]], [[7kfv]], [[7kfw]], [[7kfx]], [[7kfy]], [[7klg]], [[7klh]], [[7kmg]], [[7kmh]], [[7kmi]], [[7kn4]], [[7kzb]], [[7l0n]], [[7l2c]], [[7l5b]], [[7l7d]], [[7l7e]], [[7lm8]], [[7lm9]], [[7lop]], [[7lq7]], [[7ly3]], [[7m3i]], [[7m6d]], [[7mf1]], [[7mmo]], [[7msq]], [[7mzf]], [[7mzg]], [[7mzh]], [[7mzi]], [[7mzj]], [[7mzk]], [[7mzl]], [[7mzm]], [[7mzn]], [[7n3i]], [[7neg]], [[7neh]], [[7np1]], [[7nx6]], [[7nx7]], [[7nx8]], [[7nx9]], [[7nxa]], [[7nxb]], [[7or9]], [[7ora]], [[7orb]], [[7pry]], [[7prz]], [[7pqy]], [[7pqz]], [[7pr0]], [[7ps0]], [[7ps1]], [[7ps2]], [[7ps4]], [[7ps5]], [[7ps6]], [[7ps7]], [[7q0g]], [[7q0h]], [[7q0i]], [[7qez]], [[7qf0]], [[7qnw]], [[7qnx]], [[7qny]], [[7r6w]], [[7r6x]], [[7r8l]], [[7rku]], [[7rnj]], [[7s0b]], [[7s4s]], [[7s5p]], [[7s5q]], [[7s5r]], [[7sd5]], [[7si2]], [[7t7b]], [[7tcq]], [[7te1]], [[7tf1]], [[7tf4]], [[7tn0]], [[7tow]], [[7ttm]], [[7ttx]], [[7tty]], [[7u2d]], [[7u2e]], [[7urq]], [[7urs]], [[7vyr]], [[7wbz]], [[7wph]], [[7x7o]], [[7x9e]], [[7zf3]], [[7zf4]], [[7zf5]], [[7zf8]], [[7zf9]], [[7zfa]], [[7zfc]], [[7zfd]], [[7zfe]], [[8d36]], [[8d6z]], [[8dao]], [[8dcc]] - hFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[6nb6]], [[6nb7]], [[6wps]], [[6wpt]], [[6xcm]], [[6xcn]], [[6xdg]], [[6xey]], [[6yor]], [[6zdh]], [[6zdg]], [[6zfo]], [[7a5r]], [[7a5s]], [[7akd]], [[7akj]], [[7byr]], [[7bwj]], [[7c2l]], [[7cac]], [[7cai]], [[7cak]], [[7chh]], [[7cwl]], [[7cwm]], [[7cwn]], [[7cwo]], [[7cws]], [[7cwu]], [[7cyh]], [[7cyp]], [[7czq]], [[7czr]], [[7czs]], [[7czt]], [[7czu]], [[7czv]], [[7czw]], [[7czp]], [[7czx]], [[7d00]], [[7d03]], [[7d0b]], [[7d0c]], [[7d0d]], [[7d4g]], [[7dx4]], [[7dzx]], [[7dzy]], [[7e23]], [[7e39]], [[7e3b]], [[7e3c]], [[7e3k]], [[7e3l]], [[7e5r]], [[7e5s]], [[7e8c]], [[7e8f]], [[7e9n]], [[7e9o]], [[7e9p]], [[7e9q]], [[7eh5]], [[7ej4]], [[7ej5]], [[7ek0]], [[7enf]], [[7eng]], [[7epx]], [[7ey0]], [[7ey4]], [[7ey5]], [[7eya]], [[7ezv]], [[7f46]], [[7f62]], [[7f63]], [[7f6z]], [[7fae]], [[7faf]], [[7fjn]], [[7fjo]], [[7jv2]], [[7jv4]], [[7jv6]], [[7jva]], [[7jvc]], [[7jw0]], [[7k43]], [[7k45]], [[7k4n]], [[7k8s]], [[7k8t]], [[7k8u]], [[7k8v]], [[7k8w]], [[7k8x]], [[7k8y]], [[7k8x]], [[7k8y]], [[7k8z]], [[7k90]], [[7kmk]], [[7kml]], [[7kqb]], [[7kqe]], [[7ks9]], [[7kxj]], [[7kxk]], [[7l02]], [[7l06]], [[7l09]], [[7l2d]], [[7l2e]], [[7l2f]], [[7l3n]], [[7l56]], [[7l57]], [[7l58]], [[7laa]], [[7lab]], [[7ld1]], [[7lcn]], [[7ljr]], [[7lm8]], [[7lqv]], [[7lqw]], [[7lrs]], [[7lrt]], [[7ls9]], [[7lss]], [[7lxw]], [[7lxx]], [[7lxy]], [[7lxz]], [[7ly0]], [[7ly2]], [[7m42]], [[7m6e]], [[7m6f]], [[7m6g]], [[7m6h]], [[7m6i]], [[7m71]], [[7m7b]], [[7m8j]], [[7m8k]], [[7mkm]], [[7mlz]], [[7mm0]], [[7mw2]], [[7mw3]], [[7mw4]], [[7mw5]], [[7mw6]], [[7mxp]], [[7n5h]], [[7n62]], [[7n64]], [[7n8h]], [[7n8i]], [[7nd3]], [[7nd4]], [[7nd5]], [[7nd6]], [[7nd7]], [[7nd8]], [[7nd9]], [[7nda]], [[7ndb]], [[7ndc]], [[7ndd]], [[7ntc]], [[7p40]], [[7phg]], [[7pnm]], [[7pnq]], [[7po5]], [[7q0a]], [[7q6f]], [[7q9g]], [[7q9i]], [[7q9j]], [[7q9k]], [[7q9m]], [[7q9p]], [[7r40]], [[7r7n]], [[7r8m]], [[7r8n]], [[7r8o]], [[7ra8]], [[7ral]], [[7rb7]], [[7rbu]], [[7rkv]], [[7rq6]], [[7rr0]], [[7rw2]], [[7s0c]], [[7s0d]], [[7s0e]], [[7s6j]], [[7sb3]], [[7sb4]], [[7sbv]], [[7sbw]], [[7sbx]], [[7sby]], [[7sc1]], [[7sg4]], [[7sn2]], [[7sn3]], [[7so9]], [[7soa]], [[7sob]], [[7soc]], [[7sod]], [[7soe]], [[7sof]], [[7swn]], [[7swo]], [[7swp]], [[7t01]], [[7tas]], [[7tat]], [[7tb8]], [[7tbf]], [[7tc9]], [[7tca]], [[7tcc]], [[7the]], [[7tht]], [[7tly]], [[7tlz]], [[7tm0]], [[7u0d]], [[7uap]], [[7uaq]], [[7uar]], [[7upw]], [[7upx]], [[7upy]], [[7v23]], [[7v24]], [[7v26]], [[7v2a]], [[7v3l]], [[7we7]], [[7we8]], [[7we9]], [[7wea]], [[7web]], [[7wec]], [[7wed]], [[7wee]], [[7wef]], [[7whz]], [[7wi0]], [[7wjy]], [[7wjz]], [[7wk0]], [[7wk8]], [[7wlc]], [[7wly]], [[7wlz]], [[7wm0]], [[7wo4]], [[7wo5]], [[7wo7]], [[7woa]], [[7wob]], [[7woc]], [[7wog]], [[7won]], [[7wp0]], [[7wp1]], [[7wp2]], [[7wp5]], [[7wr8]], [[7wrl]], [[7wro]], [[7wrz]], [[7ws0]], [[7ws1]], [[7ws2]], [[7ws3]], [[7ws4]], [[7ws5]], [[7ws6]], [[7ws7]], [[7wuh]], [[7wwl]], [[7wwm]], [[7x08]], [[7x6a]], [[7xco]], [[7xck]], [[7xh8]], [[7xic]], [[7yad]], [[7zbu]], [[7zr7]], [[7zr8]], [[7zr9]], [[7zrc]], [[8dad]], [[8dlr]], [[8dls]], [[8dlt]], [[8dlw]], [[8dlx]], [[8dt3]] - hFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7sjs]] - hFab + SARS-CoV-2 spike protein peptide<br /> | ||
| + | **[[6yz7]], [[6z2m]], [[6zcz]], [[6zh9]], [[7fg2]], [[7fg3]], [[7kn6]], [[7kn7]], [[7raq]], [[7zfb]], [[7zxu]], [[8cwv]] - hFab + ViVHH + SARS-CoV-2 spike protein<br /> | ||
| + | **[[7xod]], [[8cwv]] - hFab + ViVHH + SARS-CoV-2 spike protein<br | ||
| + | **[[7n3c]], [[7n3d]], [[7str]], [[7sts]], [[7sue]] - hFab + SARS nucleoprotein<br /> | ||
| + | **[[7xcp]] - hFab + SARS-CoV-2 spike protein + ACE2 – Cryo EM<br /> | ||
| + | **[[8dfs]] - hFab + SARS-CoV-2 spike protein + ACE2<br /> | ||
| + | **[[7vnc]], [[7vnd]], [[7vne]], [[7whi]], [[7whj]], [[7whk]] - hVHH + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7wpd]], [[7wpe]], [[7wpf]] - mrFab + ViVHH + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7tp3]], [[7tp4]], [[7wue]] - mrFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7k9h]], [[7k9i]], [[7k9j]], [[7k9k]], [[7mkl]], [[7wk6]], [[7wka]], [[7wrv]], [[7x7t]], [[7x7u]], [[7x7v]] - mFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7f0x]], [[7f12]], [[7f15]], [[7s3n]] - mFab + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7m53]] - mFab + SARS-CoV-2 spike protein peptide<br /> | ||
| + | **[[7my2]], [[7my3]] – mVHH anti-SARS + SARS-CoV-2 spike protein <br /> | ||
| + | **[[7mjj]], [[7mjk]] - syFab + SARS-CoV-2 spike protein – Cryo EM<br /> | ||
| + | **[[7kkj]] – syVHH anti-SARS<br /> | ||
| + | **[[6waq]], [[6z43]], [[8cwu]] – LgVHH anti-SARS + spike protein<br /> | ||
| + | **[[7on5]] – ViVHH anti-SARS <br /> | ||
| + | **[[7f5g]], [[7f5h]], [[7kn5]], [[7ldj]], [[7olz]] – ViVHH anti-SARS + spike protein <br /> | ||
| + | **[[6zxn]] – ViVHH anti-SARS + spike protein – Cryo EM<br /> | ||
| + | **[[7c8v]], [[7c8w]], [[7can]], [[7d2z]], [[7d30]], [[7kgj]], [[7kgk]], [[7klw]], [[7mfu]] – syVHH + SARS-CoV-2 spike protein<br/> | ||
| + | **[[7a25]], [[7a29]], [[7kkk]], [[7kkl]], [[7mjl]], [[7n0g]], [[7mjh]], [[7n0h]] – syVHH + SARS-CoV-2 spike protein – Cryo EM<br/> | ||
| + | **[[7cyv]], [[7deo]], [[7det]], [[7deu]], [[7vmu]], [[8dce]] – hscFv + SARS spike protein<br /> | ||
| + | **[[7t3m]] - EcscFv + SARS-CoV spike protein – Cryo EM<br /> | ||
| + | **[[7b14]], [[7b17]], [[7b18]], [[7jvb]] - LgVHH + SARS spike glycoprotein <br /> | ||
| + | **[[7ksg]] - LgVHH + SARS spike glycoprotein – Cryo EM<br /> | ||
| + | **[[7r98]]- LgVHH + SARS nucleoprotein – Cryo EM<br /> | ||
| + | |||
| + | *Anti-MERS-CoV Fab | ||
| + | |||
| + | **[[6nb5]] - hFab anti-MERS-CoV<br /> | ||
| + | **[[6pxg]] - mFab anti-MERS-CoV<br /> | ||
| + | **[[7coe]] - hFab + MERS-CoV spike protein <br /> | ||
| + | **[[6nb3]], [[6nb4]], [[7v5k]], [[7v6n]] - hFab + MERS-CoV spike protein – Cryo EM<br /> | ||
| + | **[[6pxh]], [[6pz8]], [[7s3m]] - mFab anti-MERS-CoV + MERS-CoV protein<br /> | ||
| + | **[[6j11]] - mscFv + MERS-CoV spike protein<br /> | ||
| + | **[[6war]] - LgVHH + MERS-CoV spike protein<br /> | ||
| + | |||
| + | *Anti-hepatitis Fab | ||
| + | |||
| + | **[[6mwn]] – hFab + hepatitis A virus RNA<br /> | ||
| + | **[[4hs8]], [[5kzp]], [[7lki]] – hFab + hepatitis C virus peptide <br /> | ||
| + | **[[6bkb]], [[6bkc]], [[6bkd]], [[6mej]], [[6meh]], [[6mei]], [[6mek]], [[6u8d]], [[6u8k]], [[6uyf]], [[6urh]], [[6uyd]], [[6uyg]], [[6uym]], [[6wo3]], [[6wo4]], [[6woq]] - hFab anti-hepatitis C virus + glycoprotein<br /> | ||
| + | **[[7kql]] - hFab anti-hepatitis C virus + Hepatitis A cellular receptor<br /> | ||
| + | **[[7jtf]], [[7jtg]] - rmFab + hepatitis C envelope protein<br /> | ||
| + | **[[4why]], [[4wht]] - raFab + hepatitis C peptide<br /> | ||
| + | **[[5npi]], [[5npj]] – mscFv + hepatitis C peptide<br /> | ||
| + | **[[6jhq]], [[6jhr]], [[6jhs]], [[6jht]] - mFab + hepatitis A proteins – Cryo EM<br /> | ||
| + | **[[6cwt]] – rFab + Hepatitis B capsid<br /> | ||
| + | **[[6cwd]] – rscFv + hepatitis B capsid<br /> | ||
| + | **[[5nph]], [[6bzu]], [[6bzv]], [[6bzw]], [[6bzy]] – mFab + hepatitis C virus peptide <br /> | ||
*Human Fab: small molecule complex | *Human Fab: small molecule complex | ||
| Line 46: | Line 113: | ||
**[[3oay]], [[3oaz]], [[3ob0]], [[6msy]], [[6mub]], [[6mu3]], [[6mnf]] - hFab 2g12 + glycan<br /> | **[[3oay]], [[3oaz]], [[3ob0]], [[6msy]], [[6mub]], [[6mu3]], [[6mnf]] - hFab 2g12 + glycan<br /> | ||
**[[6n35]], [[6n2x]], [[5i8o]] - hFab + polysaccharide<br /> | **[[6n35]], [[6n2x]], [[5i8o]] - hFab + polysaccharide<br /> | ||
| + | **[[7dc7]] - hFab + ATP<br /> | ||
| + | **[[6bjz]] - hFab + fluorescent amino acid<br /> | ||
| + | **[[7kkh]] - hFab + piperazine derivative<br /> | ||
| + | **[[6o3u]] - hFab anti-HIV + PA<br /> | ||
*Mouse Fab: small molecule complex | *Mouse Fab: small molecule complex | ||
| Line 67: | Line 138: | ||
**[[1igj]] - mFab 26-10 + digoxin<br /> | **[[1igj]] - mFab 26-10 + digoxin<br /> | ||
**[[4fab]] – mFab 4-4-20 + fluorescin<br /> | **[[4fab]] – mFab 4-4-20 + fluorescin<br /> | ||
| + | **[[7f35]] – mFab + gatifloxacin<br /> | ||
**[[1dl7]] - mFab MCPC603 + phosphocholine<br /> | **[[1dl7]] - mFab MCPC603 + phosphocholine<br /> | ||
**[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br /> | **[[3cfb]], [[3cfd]], [[2g2r]] – mFab + stilbene hapten<br /> | ||
| - | **[[4kze]], [[4kzd]] – mFab + RNA <br /> | + | **[[4kze]], [[4kzd]], [[7szu]], [[7u0y]] – mFab + RNA <br /> |
| + | **[[6kdi]] - mFab anti-photoproduct + DNA<br /> | ||
*Other Fab: small molecule complex | *Other Fab: small molecule complex | ||
| Line 85: | Line 158: | ||
**[[3cxd]], [[3dsf]], [[5x5x]] – mFab + osteopontin peptide<br /> | **[[3cxd]], [[3dsf]], [[5x5x]] – mFab + osteopontin peptide<br /> | ||
**[[2zpk]] – mFab + proteinase-activated receptor peptide<br /> | **[[2zpk]] – mFab + proteinase-activated receptor peptide<br /> | ||
| - | **[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp]] - mFab + amyloid peptide<br /> | + | **[[3ifl]], [[3ifn]], [[3ifo]], [[3ifp]], [[7e6p]] - mFab + amyloid peptide<br /> |
**[[2eh8]] - mFab + PRES1 peptide<br /> | **[[2eh8]] - mFab + PRES1 peptide<br /> | ||
**[[2brr]] – mFab + outer membrane protein peptide<br /> | **[[2brr]] – mFab + outer membrane protein peptide<br /> | ||
| - | **[[1xgy]] – mFab + rhodopsin peptide<br /> | + | **[[1xgy]], [[7doh]] – mFab + rhodopsin peptide<br /> |
**[[1pz5]] – mFab SYA/J6 + peptide<br /> | **[[1pz5]] – mFab SYA/J6 + peptide<br /> | ||
**[[1a3r]] – mFab + rhinovirus capsid peptide<br /> | **[[1a3r]] – mFab + rhinovirus capsid peptide<br /> | ||
**[[1cu4]] - mFab + prion protein peptide<br /> | **[[1cu4]] - mFab + prion protein peptide<br /> | ||
**[[1fpt]] – mFab + poliovirus peptide<br /> | **[[1fpt]] – mFab + poliovirus peptide<br /> | ||
| - | **[[1jp5]] – mFab + HIV-1 protease peptide<br /> | ||
**[[1mvu]] – mFab + glycoprotein <br /> | **[[1mvu]] – mFab + glycoprotein <br /> | ||
**[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br /> | **[[2ap2]] – mFab + glycoprotein peptide + C-myc peptide<br /> | ||
| Line 99: | Line 171: | ||
**[[1tet]] – mFab + cholera toxin peptide<br /> | **[[1tet]] – mFab + cholera toxin peptide<br /> | ||
**[[5epm]] – mFab + therapotoxin peptide<br /> | **[[5epm]] – mFab + therapotoxin peptide<br /> | ||
| - | **[[5eor]], [[5eoq]] – mFab + protein A27 peptide<br /> | ||
**[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | **[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8i]], [[1i8k]] – mFab + EGFR peptide<br /> | ||
| - | **[[1i8k]] – mFab + EGFR peptide<br /> | ||
**[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | **[[4gag]], [[4gaj]] – mFab + genome polyprotein peptide<br /> | ||
| - | **[[5nph]] – mFab + hepatitis virus peptide <br /> | ||
**[[5mv4]], [[5mu0]] – mFab + collagen peptide <br /> | **[[5mv4]], [[5mu0]] – mFab + collagen peptide <br /> | ||
| + | **[[6f7t]] – mFab + RNase peptide<br /> | ||
| + | **[[7njz]], [[7nw3]] – mFab + chemokine receptor peptide<br /> | ||
| + | **[[7v4w]], [[7v64]], [[7v7k]], [[7v8q]], [[7vac]], [[7vaz]] – mFab + mucin peptide<br /> | ||
| + | **[[7o2z]], [[7o30]], [[7o31]], [[7o33]] – mFab + PAS peptide<br /> | ||
| + | **[[7fgj]], [[7fgl]], [[7fgr]] - mFab + Tau peptide<br /> | ||
*Human Fab: peptide complex | *Human Fab: peptide complex | ||
| Line 112: | Line 184: | ||
**[[3h0t]] - hFab + hepcidin peptide<br /> | **[[3h0t]] - hFab + hepcidin peptide<br /> | ||
**[[1sm3]] - hFab SM3 + peptide<br /> | **[[1sm3]] - hFab SM3 + peptide<br /> | ||
| - | **[[4why]], [[4wht]] - hFab anti-HIV + peptide<br /> | ||
**[[5ea0]] - hFab 7968 + complement factor peptide<br /> | **[[5ea0]] - hFab 7968 + complement factor peptide<br /> | ||
**[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br /> | **[[4z0x]], [[4xvj]] - hFab + HCV E2 peptide<br /> | ||
**[[3eyf]], [[4hha]] – hFab + cytomegalovirus peptide<br /> | **[[3eyf]], [[4hha]] – hFab + cytomegalovirus peptide<br /> | ||
**[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br /> | **[[2hfg]], [[2h9g]] – hFab + TNF receptor peptide<br /> | ||
| - | **[[3csy]] - hFab + Ebola envelope glycoprotein peptide<br /> | + | **[[3csy]], [[6n7j]], [[7rpu]] - hFab + Ebola envelope glycoprotein peptide<br /> |
| - | **[[ | + | **[[6h06]], [[6h0e]], [[6gk7]], [[6gk8]], [[5zia]], [[5zv3]], [[6dcw]], [[7eyc]], [[7kqk]] - hFab + Tau peptide<br /> |
| - | **[[ | + | **[[6bqb]], [[6ct7]], [[6kva]], [[6kvf]], [[6ldv]], [[6ldw]], [[6ldx]], [[7bxv]], [[7c94]], [[7y3j]] – hFab + peptide<br /> |
| - | **[[ | + | **[[6e4y]], [[6e4z]], [[6mv5]] - hFab + PCSK9 peptide<br /> |
| + | **[[7jwq]] - hFab + IL-1b peptide<br /> | ||
| + | **[[7jwp]] - hFab + IL-18 peptide<br /> | ||
| + | **[[7sfx]] - hFab + CD99 peptide<br /> | ||
| + | **[[7um3]] - hFab + LAG3 peptide<br /> | ||
| + | **[[7rta]] - hFab + neuropeptide Y<br /> | ||
| + | **[[7k7r]] - hFab + EBNA1 peptide<br /> | ||
| + | **[[7rt9]] - hFab + YY peptide<br /> | ||
| + | **[[7s4g]] - hFab + Ly6G6D peptide<br /> | ||
| + | **[[7ow1]], [[7oxn]] - hFab + amyloid peptide<br /> | ||
*Other Fab: peptide complex | *Other Fab: peptide complex | ||
| Line 126: | Line 206: | ||
**[[2hh0]] – hmFab + prion protein peptide<br /> | **[[2hh0]] – hmFab + prion protein peptide<br /> | ||
**[[3bky]] – hmFab + CD20 peptide<br /> | **[[3bky]] – hmFab + CD20 peptide<br /> | ||
| - | **[[5dmg]] – rFab + microtubule-associated protein peptide | + | **[[5dmg]] – rFab + microtubule-associated protein peptide<br /> |
| + | **[[6ldy]], [[6x1s]], [[6x1t]], [[6x1u]], [[6x1v]], [[6x1w]] – rFab + peptide<br /> | ||
**[[5dd0]] – rmFab + peptide<br /> | **[[5dd0]] – rmFab + peptide<br /> | ||
**[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br /> | **[[6df1]], [[6df2]] - syFab anti-phosphotyrosine + phosphotyrosine peptide<br /> | ||
| Line 132: | Line 213: | ||
*Anti-HIV Fab: peptide complex | *Anti-HIV Fab: peptide complex | ||
| - | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[ | + | **[[3egs]], [[3drt]], [[3drq]], [[3dro]], [[2fx7]], [[2fx8]], [[2fx9]], [[2cmr]], [[1tzg]], [[1tjg]], [[3mnw]], [[3moa]], [[3mob]], [[3mod]], [[1tjh]], [[1tji]], [[1u8h]], [[1u8i]], [[1u8j]], [[1u8k]], [[1u8l]], [[1u8m]], [[1u8n]], [[1u8o]], [[1u8p]], [[1u8q]], [[1u91]], [[1u92]], [[1u93]], [[1u95]], [[2f5b]], [[3go1]], [[5drz]], [[6o42]] - hFab anti-HIV + gp41 peptide<br /> |
**[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | **[[3ghb]], [[3ghe]], [[3c2a]] - hFab anti-HIV + envelope glycoprotein peptide<br /> | ||
| - | **[[3fn0]], [[2oqj]] - hFab + peptide<br /> | + | **[[3fn0]], [[2oqj]], [[6fy0]], [[6fy3]], [[6mtp]], [[6mtt]], [[6ncp]], [[6o3j]] - hFab anti-HIV + peptide<br /> |
| - | **[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> | + | **[[2b0s]], [[2b1a]], [[2b1h]], [[3se8]], [[3se9]], [[4jkp]], [[4jpv]], [[4jb9]], [[6vbo]], [[6vbp]], [[6vbq]] - hFab anti-HIV + glycoprotein gp120 peptide<br /> |
**[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br /> | **[[1nak]], [[2f58]], [[3f58]], [[1f58]], [[1acy]], [[1qnz]] - mFab anti-HIV + glycoprotein gp120 peptide<br /> | ||
**[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br /> | **[[1ai1]], [[1ggi]] – mFab anti-HIV + V3 peptide<br /> | ||
**[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br /> | **[[3o6l]], [[3o6m]] - mFab 11H6H1 anti-HIV + Tat peptide<br /> | ||
| - | **[[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br /> | + | **[[1jp5]], [[1svz]] - mFab anti-HIV + HIV-2 protease peptide<br /> |
| + | **[[6p8d]], [[6p8n]], [[6pdr]], [[6pdu]], [[6ubi]], [[6uce]], [[6ucf]], [[6wwc]], [[6wx2]] – mFab + HIV-1 fusion peptide<br /> | ||
| + | **[[6mqc]], [[6mqe]], [[6mqm]], [[6mqr]], [[6mqs]], [[6n16]], [[6pds]], [[6pec]], [[6pef]] - rmFab + HIV fusion peptide<br /> | ||
| + | **[[6mnq]], [[6mnr]], [[6mns]] - rmFab anti-HIV + gp120 peptide<br /> | ||
| + | **[[6p60]], [[6p7h]] - Fab + HIV fusion peptide - platytthini<br /> | ||
*Human Fab: protein complex | *Human Fab: protein complex | ||
| Line 146: | Line 231: | ||
**[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | **[[3h42]] - hFab LDLR + proprotein convertase subtilisin/kexin<br /> | ||
**[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | **[[3nh7]] – hFab ABD1556 + bone morphogenetic protein receptor<br /> | ||
| - | **[[3hi6]] – hFab | + | **[[3hi6]] – hFab + integrin<br /> |
| + | **[[6avq]], [[6avr]], [[6avu]], [[7usl]] – hFab + integrin – Cryo EM<br /> | ||
**[[2vxs]], [[5fhx]] - hFab + interleukin<br /> | **[[2vxs]], [[5fhx]] - hFab + interleukin<br /> | ||
**[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | **[[3b2u]], [[3b2v]] – hFab IMC-11F8 + EGFR<br /> | ||
**[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | **[[2r0k]], [[2r0l]] – hFab + HGFA<br /> | ||
**[[3be1]], [[3n85]], [[1n8z]], [[6att]] - hFab + ERBB-2<br /> | **[[3be1]], [[3n85]], [[1n8z]], [[6att]] - hFab + ERBB-2<br /> | ||
| - | **[[ | + | **[[7d85]] - hFab + ERB-3<br /> |
**[[3kr3]] – hFab + IGF-II<br /> | **[[3kr3]] – hFab + IGF-II<br /> | ||
| + | **[[7o52]] – hFab + CD22<br /> | ||
| + | **[[6yio]], [[7f9w]] – hFab + CD25<br /> | ||
| + | **[[7sgm]] – hFab + CD40<br /> | ||
| + | **[[7myz]] – hFab + CD47<br /> | ||
| + | **[[7chy]], [[7chz]] - hFab + IL-1b <br /> | ||
| + | **[[6oel]] – hFab + IL-4R<br /> | ||
| + | **[[7dc8]] – hFab + IL-6R<br /> | ||
| + | **[[7rew]] – hFab + IL-13R<br /> | ||
| + | **[[6plh]] – hFab + IL-21R<br /> | ||
| + | **[[6u6u]] – hFab + IL-36R<br /> | ||
| + | **[[6ppg]], [[6wio]] - hFab + IL-17<br /> | ||
| + | **[[7wkx]] – hFab + IL-17A<br /> | ||
| + | **[[6hga]], [[6ppg]] – hFab + IL-17R<br /> | ||
**[[3g6d]] – hFab CNTO607 + IL-13<br /> | **[[3g6d]] – hFab CNTO607 + IL-13<br /> | ||
| - | **[[3g6j]] – hFab + complement C3<br /> | + | **[[3g6j]], [[7ue9]] – hFab + complement C3<br /> |
**[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br /> | **[[2wub]], [[3k2u]] – hFab 40 + hepatocyte growth factor activator<br /> | ||
| + | **[[6iz9]] – hFab + hepatocyte growth factor<br /> | ||
| + | **[[6i04]] – hFab + hepatocyte growth factor receptor<br /> | ||
| + | **[[6ktr]] - hFab + fibroblast growth factor <br /> | ||
**[[3grw]] - hFab + fibroblast growth factor receptor<br /> | **[[3grw]] - hFab + fibroblast growth factor receptor<br /> | ||
**[[6ba5]] - hFab + tyrosine protein kinase receptor<br /> | **[[6ba5]] - hFab + tyrosine protein kinase receptor<br /> | ||
| - | **[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]], [[5fv2]], [[5fv1]] | + | **[[3bdy]], [[2qr0]], [[2fjg]], [[2fjh]], [[1cz8]], [[5fv2]], [[5fv1]], [[6t9d]], [[7kez]], [[7kf0]], [[7kf1]] – hFab + VEGF<br /> |
| - | + | ||
**[[1adq]] – hFab IGM + igG1 Fc<br /> | **[[1adq]] – hFab IGM + igG1 Fc<br /> | ||
| + | **[[6eyo]], [[7si0]] – hFab + igE<br /> | ||
**[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br /> | **[[3dvg]], [[3dvn]] – hFab igG1 + ubiquitin<br /> | ||
| - | **[[3bn9]] – hFab E2 + | + | **[[3bn9]], [[7sjn]], [[7sjo]] – hFab E2 + serine protease<br /> |
**[[2jix]] – hFab ABT-007 + erythropoietin receptor<br /> | **[[2jix]] – hFab ABT-007 + erythropoietin receptor<br /> | ||
| - | **[[1za3]] - hFab | + | **[[1za3]], [[6t3j]] - hFab + TNF receptor<br /> |
| + | **[[6ogx]], [[6okm]], [[6okn]] - hFab + TNFRSF4<br /> | ||
**[[3l95]] – hFab + NRR1<br /> | **[[3l95]] – hFab + NRR1<br /> | ||
**[[1uj3]], [[4dtg]] – hFab + tissue factor<br /> | **[[1uj3]], [[4dtg]] – hFab + tissue factor<br /> | ||
**[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br /> | **[[3lev]] – hFab 2F5 + RNA polymerase sigma factor<br /> | ||
| - | **[[3ru8]] – hFab | + | **[[3ru8]], [[6mto]], [[6mtq]], [[6s3d]] – hFab + scaffold <br /> |
**[[3skj]] – hFab + ephrin receptor<br /> | **[[3skj]] – hFab + ephrin receptor<br /> | ||
**[[3sob]] – hFab + LPR6<br /> | **[[3sob]] – hFab + LPR6<br /> | ||
| Line 174: | Line 277: | ||
**[[5c8j]] – hFab + protein MJ0480<br /> | **[[5c8j]] – hFab + protein MJ0480<br /> | ||
**[[4zso]] – hFab + natural cytotoxicity triggering receptor<br /> | **[[4zso]] – hFab + natural cytotoxicity triggering receptor<br /> | ||
| - | **[[4rrp]] - hFab + | + | **[[4rrp]], [[6ayz]], [[6az2]] - hFab + ASF1 <br /> |
**[[4qci]] - hFab + platelet factor B<br /> | **[[4qci]] - hFab + platelet factor B<br /> | ||
| + | **[[7ket]], [[7lcv]] - hFab + factor H BP<br /> | ||
**[[4mxv]] - hFab + lymphotoxin <br /> | **[[4mxv]] - hFab + lymphotoxin <br /> | ||
| - | **[[5dmj]], [[5ihl]] - hFab + CD40 <br /> | + | **[[7seg]] - hFab + CD16 <br /> |
| - | **[[ | + | **[[6al5]] - hFab + CD19 <br /> |
| - | **[[3vga]] – hFab + adenosine receptor | + | **[[5dmj]], [[5ihl]], [[6fax]], [[6pe8]], [[6pe9]] - hFab + CD40 <br /> |
| + | **[[6hxw]] - hFab + CD73 <br /> | ||
| + | **[[3vg9]], [[3vga]] – hFab + adenosine receptor<br /> | ||
**[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br /> | **[[2qqk]], [[2qql]], [[2qqn]] – hFab + neuropilin<br /> | ||
**[[2vyr]] – hFab + MDM4<br /> | **[[2vyr]] – hFab + MDM4<br /> | ||
**[[6b0h]], [[6b0g]], [[6b0e]], [[6b0a]], [[6b08]], [[6azz]] - hFab + PFS25 <br /> | **[[6b0h]], [[6b0g]], [[6b0e]], [[6b0a]], [[6b08]], [[6azz]] - hFab + PFS25 <br /> | ||
| - | **[[ | + | **[[6hhc]], [[6r8x]], [[7ahu]], [[7k66]], [[7kbt]] - hFab + coagulation factor <br /> |
| - | **[[5oca]] - hFab + PCSK9 <br /> | + | **[[5oca]], [[6u36]], [[6u38]] - hFab + PCSK9 <br /> |
**[[5n88]] - hFab + SFRS1-interacting protein <br /> | **[[5n88]] - hFab + SFRS1-interacting protein <br /> | ||
**[[5bk1]], [[5bjz]] - hFab + maltose-binding protein <br /> | **[[5bk1]], [[5bjz]] - hFab + maltose-binding protein <br /> | ||
| - | **[[4hj0]] - hFab + GIPR <br /> | + | **[[4hj0]], [[6dkj]] - hFab + GIPR <br /> |
**[[4g80]], [[4g7y]], [[4g7v]] - hFab + VSP <br /> | **[[4g80]], [[4g7y]], [[4g7v]] - hFab + VSP <br /> | ||
**[[6cyf]] – hFab + secretion system protein<br /> | **[[6cyf]] – hFab + secretion system protein<br /> | ||
| + | **[[6cw3]] – hFab + histone acetyltransferase <br /> | ||
| + | **[[6m58]] – hFab + serum albumin<br /> | ||
| + | **[[6mvl]] – hFab + VISTA<br /> | ||
| + | **[[6nmr]], [[6nms]], [[6nmt]], [[6nmu]], [[6nmv]], [[7kpg]] – hFab + SIRP-alpha<br /> | ||
| + | **[[6o39]] – hFab + frizzled-5<br /> | ||
| + | **[[6o3a]], [[6o3b]] – hFab + frizzled-7<br /> | ||
| + | **[[6phb]], [[6phc]], [[6phd]], [[6phf]] – hFab + PFS25<br /> | ||
| + | **[[6r0x]] – hFab + G6B<br /> | ||
| + | **[[6o41]], [[6u8c]] – hFab + protein G<br /> | ||
| + | **[[6xxv]] – hFab + S2_1.2<br /> | ||
| + | **[[6c9u]], [[6mlk]] – hFab + DEBS<br /> | ||
| + | **[[7m7e]], [[7m7f]], [[7m7g]], [[7m7h]], [[7m7i]], [[7m7j]], [[7s6c]], [[7s6d]] – hFab + DEBS – Cryo EM<br /> | ||
| + | **[[6o9h]] – hFab + ECD<br /> | ||
| + | **[[7dm1]], [[7dm2]] – hFab + PstS-1<br /> | ||
| + | **[[6vgr]] - hFab + dipeptidase<br /> | ||
| + | **[[6vvu]] - hFab + tryptase<br /> | ||
| + | **[[6j14]], [[6j15]], [[7c88]], [[7e9b]], [[7vux]], [[7wsl]] - hFab + PD-1<br /> | ||
| + | **[[6vc9]], [[6vca]] - hFab + nucleotidase<br /> | ||
| + | **[[6i3z]] - hFab anti-antitrypsin + antitrypsin<br /> | ||
| + | **[[6xy2]], [[7elx]], [[7su0]], [[7su1]] – hFab + CTLA<br /> | ||
| + | **[[6xmi]] – hFab + terminase<br /> | ||
| + | **[[6cbv]] – hFab + BRIL<br /> | ||
| + | **[[7khf]] – hFab + rifin<br /> | ||
| + | **[[6y9b]] – hFab + STEAP1<br /> | ||
| + | **[[6fn4]] – hFab + ABCB<br /> | ||
| + | **[[7neq]], [[7nfd]] – hFab + ABCG2 – Cryo EM<br /> | ||
| + | **[[7nez]] – hFab + ABCG2 + drug – Cryo EM<br /> | ||
| + | **[[6bdz]] – hFab + ADAM-10<br /> | ||
| + | **[[7c61]] – hFab + HT1B<br /> | ||
| + | **[[6m3b]], [[6m3c]] – hFab + vitamin K-dependent protein<br /> | ||
| + | **[[7mxl]] - hFab + pollen allergen – Cryo EM<br /> | ||
| + | **[[7ssv]] - hFab + Kv1.3 – Cryo EM<br /> | ||
| + | **[[7phu]] – hFab + RH5<br /> | ||
| + | **[[7ce2]], [[7oh0]], [[7oh1]] – hFab + tetanus toxin<br /> | ||
| + | **[[7vyt]] – hFab + TIGIT<br /> | ||
| + | **[[7bbj]] – hFab + nucleotidase<br /> | ||
| + | **[[7lj4]], [[7lj5]], [[7lja]], [[7ljb]] – hFab + TRAAK <br /> | ||
| + | **[[7fci]], [[7vad]] – hFab + NTCP – Cryo EM<br /> | ||
| + | **[[7lk4]] – hFab + Bcl-2<br /> | ||
| + | **[[7daa]] – hFab + basigin<br /> | ||
| + | **[[7mnl]], [[7mnm]], [[7mnn]], [[7mno]] – hFab + NUP358/RanBP<br /> | ||
| + | **[[7ahv]] – hFab + FIXa<br /> | ||
| + | **[[7cj2]] – hFab + YAK-40<br /> | ||
| + | **[[7e72]] – hFab + angiopoietin receptor<br /> | ||
| + | **[[7rco]] – hFab + TGF <br /> | ||
| + | **[[7mlh]] – hFab + Der p 2 <br /> | ||
| + | **[[7t0w]], [[7t0z]] – hFab + GABA – Cryo EM<br /> | ||
| + | **[[6ddm]], [[6ddv]] – hFab + MHC<br /> | ||
| + | **[[7pg8]], [[7pgb]] – hFab + Na+ channel<br /> | ||
| + | **[[7kzx]], [[7kzz]] – hFab + YiiP <br /> | ||
| + | **[[7amp]], [[7amq]], [[7amr]], [[7ams]] – hFab + T-cell receptor<br /> | ||
| + | **[[7dfp]] – hFab + Gi + dopamine receptor + drug – Cryo EM<br /> | ||
| + | **[[7lf7]], [[7lf8]], [[7lfa]], [[7lfb]], [[7lfd]] – hFab + ApoL <br /> | ||
| + | **[[7rth]] – hFab + hVHH <br /> | ||
| + | **[[7n0a]] – hFab + leukemia inhibitory factor <br /> | ||
| + | **[[6j6y]] – syFab + FGFR4<br /> | ||
*Human Fab: viral protein complex | *Human Fab: viral protein complex | ||
| - | **[[6e3h]], [[6d0u]], [[5vag]], [[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]], [[5wko]], [[5w6g]], [[5w0d]], [[5w08]], [[5v2a]], [[5umn]], [[5kaq]], [[6ml8]] | + | **[[6e3h]], [[6d0u]], [[5vag]], [[3gbm]], [[3gbn]], [[3lzf]], [[3fku]], [[3sdy]], [[3ztj]], [[3ztn]], [[4fp8]], [[4fqi]], [[4fqj]], [[4fqk]], [[4fql]], [[4fqr]], [[4fqv]], [[4fqy]], [[4gxu]], [[4nm8]], [[5gjt]], [[5gjs]], [[5dur]], [[5c0s]], [[4yk4]], [[4py8]], [[5wko]], [[5w6g]], [[5w0d]], [[5w08]], [[5v2a]], [[5umn]], [[5kaq]], [[6cnv]], [[6e4x]], [[6ii4]], [[6ii8]], [[6ii9]], [[6ml8]], [[6e56]], [[4r8w]], [[6iut]], [[6iuv]], [[6oc3]], [[6ocb]], [[6p3r]], [[6q0e]], [[6q0h]], [[6q0i]], [[6q0l]], [[6q0o]], [[6q18]], [[6uig]], [[6ur5]], [[6urm]], [[6uyn]], [[6wex]], [[6wez]], [[6wf0]], [[6wf1]], [[6wiz]], [[6wj1]], [[7kqg]], [[7kqh]], [[7kqi]], [[7u8j]], [[7u8l]], [[7u8m]] – hFab + Influenza virus hemagglutinin<br /> |
| - | **[[5gzo]], [[5gzn]], [[ | + | **[[7k37]], [[7k39]], [[7k3a]], [[7k3b]], [[7kc1]], [[7l0l]], [[7mfg]], [[7scn]], [[7sco]], [[7x6l]], [[7x6o]] – hFab + Influenza virus hemagglutinin – Cryo EM<br /> |
| - | **[[5hj3]], [[5fhc]] – hFab + ebola envelope protein<br /> | + | **[[6pze]], [[6pzf]], [[6pzy]], [[6pzz]], [[6q1z]], [[6q20]], [[6q23]], [[6u02]] – hFab + Influenza virus neuraminidase<br /> |
| - | **[[ | + | **[[6pzw]], [[6pzy]], [[6pzz]], [[6v4n]], [[6v4o]] – hFab + Influenza virus neuraminidase – Cryo EM<br /> |
| - | **[[ | + | **[[5gzo]], [[5gzn]], [[5lcv]], [[6nip]], [[6niu]], [[6plk]] – hFab + zika protein<br /> |
| - | **[[5n09]], [[4utb]], [[4uta]], [[4ut9]], [[4ut6]] | + | **[[6lnt]], [[7bu8]], [[7bua]], [[7cbp]], [[7c2t]], [[7kcr]] – hFab + zika proteins – Cryo EM<br /> |
| - | **[[4c2i]] – hFab + dengue virus envelope protein - Cryo EM<br /> | + | **[[7bsd]] – hFab + zika virus NS1c <br /> |
| - | **[[4dag]] – hFab + metapneumovirus glycoprotein F0<br /> | + | **[[7lse]], [[7lsf]] – hFab + tick-borne encephalitis virus proteins <br /> |
| - | **[[ | + | **[[7lsg]], [[7sfv]], [[7sfw]] – hFab + tick-borne encephalitis virus proteins – Cryo EM<br /> |
| + | **[[6xob]] – hFab + eastern equine encephalitis virus protein - Cryo EM<br /> | ||
| + | **[[7ums]] – hFab + rotavirus proteins – Cryo EM<br /> | ||
| + | **[[5hj3]], [[5fhc]], [[6oz9]], [[6s8d]], [[6s8i]], [[6s8j]] – hFab + ebola envelope protein<br /> | ||
| + | **[[7kej]] – hFab + ebola spike glycoprotein – Cryo EM<br /> | ||
| + | **[[7kew]], [[7kex]], [[7kf9]], [[7kfb]], [[7kfe]], [[7kfh]], [[7m8l]], [[7swd]] – hFab + spike glycoprotein + ebola envelope protein – Cryo EM<br /> | ||
| + | **[[5n09]], [[4utb]], [[4uta]], [[4ut9]], [[4ut6]] – hFab + dengue virus envelope protein <br /> | ||
| + | **[[4c2i]], [[7bub]], [[7bud]], [[7bue]], [[7buf]], [[7c2s]], [[7v3g]], [[7v3h]], [[7v3i]], [[7v3j]] – hFab + dengue virus envelope protein - Cryo EM<br /> | ||
| + | **[[7bsc]] – hFab + dengue virus NS1c <br /> | ||
| + | **[[6vy4]], [[6vy6]] – hFab + Hendra virus protein<br /> | ||
| + | **[[6ute]] – hFab + West NIle virus protein<br /> | ||
| + | **[[6vy5]] – hFab + nipa virus receptor binding protein<br /> | ||
| + | **[[6blh]], [[6bli]], [[6oe4]], [[6ous]], [[6w52]] – hFab + RSV fusion protein<br /> | ||
| + | **[[7luc]], [[7lue]], [[7mpg]] – hFab + RSV fusion protein – Cryo EM<br /> | ||
| + | **[[7t8w]] – hFab + RSV glycoprotein <br /> | ||
| + | **[[6mjz]] – hFab + respirovirus fusion protein<br /> | ||
| + | **[[4dag]], [[7sem]] – hFab + metapneumovirus glycoprotein F0<br /> | ||
| + | **[[7tl0]], [[8cw9]] – hFab + metapneumovirus glycoprotein F0 – Cryo EM<br /> | ||
| + | **[[6p91]], [[6p95]], [[7s8h]] – hFab + lassa virus glycoprotein <br /> | ||
| + | **[[7tyv]], [[7uds]], [[7ul7]] – hFab + lassa virus glycoprotein – Cryo EM<br /> | ||
| + | **[[7t4s]] – hFab + HCMV glycoprotein – Cryo EM<br /> | ||
| + | **[[7l7r]] – hFab + hemorrhagic fever virus glycoprotein <br /> | ||
| + | **[[6yo6]] – hFab + LgHC3NB1<br /> | ||
| + | **[[7jie]] – hFab + norovirus VP1<br /> | ||
| + | **[[6gv4]] – hFab + parechovirus proteins + RNA - Cryo EM<br /> | ||
| + | **[[7d5z]], [[7kbb]] – hFab + herpesvirus proteins <br /> | ||
| + | **[[6c5v]], [[7fbi]], [[7kdd]], [[7lbe]], [[7lbf]], [[7lbg]], [[7m30]], [[7t4q]], [[7t4r]] – hFab + herpesvirus proteins - Cryo EM<br /> | ||
| + | **[[6b9j]] – syFab + vaccinia virus protein<br /> | ||
| + | **[[6otc]] – syFab + Marburg virus protein<br /> | ||
| + | **[[6svl]] – syFab + MYDGF<br /> | ||
| + | **[[7mmn]] – Fab + Escherichia virus protein<br /> | ||
*Mouse Fab: protein complex | *Mouse Fab: protein complex | ||
**[[1tzh]], [[1tzi]] - mFab + VEGF<br /> | **[[1tzh]], [[1tzi]] - mFab + VEGF<br /> | ||
| - | **[[1fsk]] - mFab + pollen allergen<br /> | + | **[[1fsk]], [[5vfy]], [[7n0v]] - mFab + pollen allergen<br /> |
**[[3raj]] – mFab HB7 + CD38<br /> | **[[3raj]] – mFab HB7 + CD38<br /> | ||
| + | **[[6u9s]] – mFab 5A6 + CD81<br /> | ||
| + | **[[7s11]], [[7s13]] – mFab + CD96<br /> | ||
**[[3o0r]], [[5gux]] – mFab + nitric oxide reductase<br /> | **[[3o0r]], [[5gux]] – mFab + nitric oxide reductase<br /> | ||
**[[1ahw]] - mFab 5G9+ tissue factor<br /> | **[[1ahw]] - mFab 5G9+ tissue factor<br /> | ||
| - | **[[2w9e]], [[1tpx]], [[1tqb]], [[1tqc]] – mFAB + major prion protein<br /> | + | **[[2w9e]], [[1tpx]], [[1tqb]], [[1tqc]], [[6aq7]], [[6suz]], [[6sv2]] – mFAB + major prion protein<br /> |
**[[2oz4]] – mFab + intercellular adhesion molecule<br /> | **[[2oz4]] – mFab + intercellular adhesion molecule<br /> | ||
**[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br /> | **[[3eo1]] - mFab GC-1008 + transforming growth factor β-3<br /> | ||
| + | **[[6z7w]], [[6z7y]], [[6z7z]] – mFab + insulin<br /> | ||
**[[4zxb]] – mFab 83 + insulin receptor<br /> | **[[4zxb]] – mFab 83 + insulin receptor<br /> | ||
**[[1egj]] – mFab + cytokine receptor<br /> | **[[1egj]] – mFab + cytokine receptor<br /> | ||
| Line 220: | Line 415: | ||
**[[1qfw]] – mFab + gonadotropin<br /> | **[[1qfw]] – mFab + gonadotropin<br /> | ||
**[[4cad]] – mFab + RCE1<br /> | **[[4cad]] – mFab + RCE1<br /> | ||
| - | **[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]] – mFab + dopamine transporter<br /> | + | **[[4m48]], [[4xpt]], [[4xph]], [[4xpg]], [[4xpf]], [[4xpb]], [[4xpa]], [[4xp9]], [[4xp6]], [[4xp5]], [[4xp4]], [[4xp1]], [[4xnx]], [[4xnu]], [[6m0f]], [[6m3z]], [[7wgd]], [[7wgt]], [[7wlw]] – mFab + dopamine transporter<br /> |
| - | **[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]], [[6awq]], [[6awp]], [[6awo]], [[6awn]] – mFab + serotonin transporter<br /> | + | **[[5i75]], [[5i74]], [[5i73]], [[5i71]], [[5i6z]], [[5i6x]], [[6awq]], [[6awp]], [[6awo]], [[6awn]], [[6w2b]], [[6w2c]] – mFab + serotonin transporter<br /> |
| + | **[[6dzv]], [[6dzw]], [[6dzy]], [[6dzz]], [[6vrh]], [[6vrk]], [[6vrl]], [[7li6]], [[7li7]], [[7li8]], [[7li9]], [[7lia]], [[7lwd]], [[7mgw]] – mFab + serotonin transporter – Cryo EM<br /> | ||
**[[1yjd]] – mFab 5.11A1 + CD28<br /> | **[[1yjd]] – mFab 5.11A1 + CD28<br /> | ||
**[[1sy6]] – mFab OKT3 + CD3<br /> | **[[1sy6]] – mFab OKT3 + CD3<br /> | ||
| Line 227: | Line 423: | ||
**[[4r0l]] – mFab + CD28<br /> | **[[4r0l]] – mFab + CD28<br /> | ||
**[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | **[[4qex]], [[4k2u]] – mFab + erythrocyte binding antigen<br /> | ||
| - | **[[2r9h]] | + | **[[2r9h]], [[6ad7]], [[6ad8]], [[6ada]], [[6adb]], [[6adc]], [[6k5a]], [[6k5i]], [[7cvs]], [[7cvt]] – mFab + exchange transporter ClCA<br /> |
| - | + | ||
**[[1rjl]] – mFab + outer surface protein<br /> | **[[1rjl]] – mFab + outer surface protein<br /> | ||
**[[1mhh]] – mFab + protein L (mutant)<br /> | **[[1mhh]] – mFab + protein L (mutant)<br /> | ||
| Line 234: | Line 429: | ||
**[[2jel]] – mFab JEL42 + histidine-containing protein<br /> | **[[2jel]] – mFab JEL42 + histidine-containing protein<br /> | ||
**[[1nsn]] – mFab N10 + nuclease<br /> | **[[1nsn]] – mFab N10 + nuclease<br /> | ||
| - | **[[1nfd]] – mFab H57 + T-cell receptor<br /> | ||
**[[1igc]] – mFab MOPC21 + streptococcal protein G<br /> | **[[1igc]] – mFab MOPC21 + streptococcal protein G<br /> | ||
**[[1iai]] – mFab idiotipic + mFab anti-idiotypic<br /> | **[[1iai]] – mFab idiotipic + mFab anti-idiotypic<br /> | ||
| + | **[[7jlk]], [[7jln]] – mFab anti-idiotypic + hFab<br /> | ||
**[[2r8s]] – mFab + RNA<br /> | **[[2r8s]] – mFab + RNA<br /> | ||
**[[2fr4]], [[1xf2]], [[1xf3]], [[1xf4]], [[1i8m]], [[1cbv]], [[6idg]] – mFab + DNA<br /> | **[[2fr4]], [[1xf2]], [[1xf3]], [[1xf4]], [[1i8m]], [[1cbv]], [[6idg]] – mFab + DNA<br /> | ||
| + | **[[7xlt]] – mFab + DNA + RNA – Cryo EM<br /> | ||
**[[1mhp]], [[3q3g]], [[3qa3]] – mFab + integrin<br /> | **[[1mhp]], [[3q3g]], [[3qa3]] – mFab + integrin<br /> | ||
| - | **[[3etb]] – mFab M18 (mutant) + anthrax-protective antigen<br /> | + | **[[3etb]], [[7o85]] – mFab M18 (mutant) + anthrax-protective antigen<br /> |
**[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]], [[4uuj]] – mFab + KcsA K+ channel<br /> | **[[3f5w]], [[3pjs]], [[3efd]], [[3eff]], [[2hjf]], [[2w0f]], [[4msw]], [[4uuj]] – mFab + KcsA K+ channel<br /> | ||
| - | **[[3stl]], [[3stz]], [[4i9w]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]] - mFab + KcsA K+ channel (mutant)<br /> | + | **[[3stl]], [[3stz]], [[4i9w]], [[5ec2]], [[5ec1]], [[5ebw]], [[5ebm]], [[5ebl]], [[5e1a]], [[6nfu]], [[6nfv]], [[6pa0]] - mFab + KcsA K+ channel (mutant)<br /> |
| - | **[[1kb5]] – mFab + T-cell receptor<br /> | + | **[[1kb5]], [[1nfd]] – mFab + T-cell receptor<br /> |
**[[4i18]] – mFab + pro-lactin receptor<br /> | **[[4i18]] – mFab + pro-lactin receptor<br /> | ||
**[[1uwx]] – mFab + protein G prime <br /> | **[[1uwx]] – mFab + protein G prime <br /> | ||
| Line 254: | Line 450: | ||
**[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br /> | **[[5d96]], [[5d93]] - mFab + sulfhydryl oxidase<br /> | ||
**[[4ybq]] – mFab + fructose transporter<br /> | **[[4ybq]] – mFab + fructose transporter<br /> | ||
| - | **[[4xzu]] - mFab + coagulation factor <br /> | + | **[[4xzu]], [[7kbt]] - mFab + coagulation factor <br /> |
**[[4u6h]] - mFab + virion membrane protein M25 <br /> | **[[4u6h]] - mFab + virion membrane protein M25 <br /> | ||
**[[4r9y]], [[4r97]] - mFab + platelet factor 4<br /> | **[[4r9y]], [[4r97]] - mFab + platelet factor 4<br /> | ||
**[[4qww]] - mFab + acetylcholinesterase <br /> | **[[4qww]] - mFab + acetylcholinesterase <br /> | ||
**[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | **[[4qti]] – mFab + urokinase-type plasminogen activator <br /> | ||
| - | ** | + | **[[5vco]] – mFab + peptidase<br /> |
**[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | **[[4p3d]], [[4p3c]] – mFab + metalloproteinase 14<br /> | ||
**[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | **[[4ong]], [[4onf]] - mFab + amyloid-β A4 protein<br /> | ||
**[[4oii]] - mFab + NS1<br /> | **[[4oii]] - mFab + NS1<br /> | ||
| - | **[[3fmg]] – mFab + glycoprotein VP7<br /> | ||
**[[5ldn]] – mFab + hexon C5<br /> | **[[5ldn]] – mFab + hexon C5<br /> | ||
| + | **[[5ldn]] – mFab + MIG-C4<br /> | ||
| + | **[[6vx4]] – mFab + toxins – Cryo EM<br /> | ||
| + | **[[6elu]] – mFab + Trypanosoma protein<br /> | ||
| + | **[[6k65]] – mFab + immunoglobulin G-binding protein<br /> | ||
| + | **[[6ks0]], [[6ks1]] – mFab + adiponectin receptor protein<br /> | ||
| + | **[[7dr4]] – mFab + IL-2<br /> | ||
| + | **[[6sxi]] – mFab + scFv<br /> | ||
| + | **[[6z2l]] – mFab + P113<br /> | ||
| + | **[[7kr5]] – mFab + CRAC – Cryo EM<br /> | ||
| + | **[[6nyq]] – mFab + GLMP<br /> | ||
| + | **[[6vtw]] – mFab + RSV S4<br /> | ||
| + | **[[7st8]] – mFab + SAS1B<br /> | ||
| + | **[[7vae]], [[7vaf]], [[7vag]], [[7wsi]] – mFab + NTCP – Cryo EM<br /> | ||
| + | **[[7xw6]] – mFab in ML109 complex – Cryo EM<br /> | ||
| + | **[[7lr3]], [[7lr4]] – mFab + hapless 2<br /> | ||
| + | **[[7kpj]] – mFab + Crohn diseae protein<br /> | ||
| + | **[[7c4s]] – mFab + S1P3<br /> | ||
| + | **[[7k7h]], [[7k7i]] – mFab + PltB – Cryo EM<br /> | ||
| + | **[[7rah]] – mFab + adenylate cyclase toxin<br /> | ||
| + | **[[7sbd]], [[7sbg]] – mFab + profilin<br /> | ||
| + | **[[7n0u]] – mFab + bet v 1<br /> | ||
| + | **[[7r9d]] – mFab + viVHH<br /> | ||
| + | **[[7jgj]] – mFab + IgA1<br /> | ||
| + | **[[7rd5]] – mFab + tetraspanin<br /> | ||
| + | **[[7te6]] – mFab + NMDA<br /> | ||
| + | **[[7te9]], [[7teb]], [[7tee]], [[7teq]], [[7ter]], [[7tes]], [[7tet]] – mFab + NMDA – Cryo EM<br /> | ||
| + | **[[7tuf]], [[7tug]] – mFab + tapasin<br /> | ||
*Mouse Fab: viral protein complex | *Mouse Fab: viral protein complex | ||
| - | **[[6a0z]], [[1eo8]], [[1ken]], [[4mhh]], [[4mhj]] - mFab anti-influenza virus hemagglutinin<br /> | + | **[[6a0z]], [[1eo8]], [[1ken]], [[4mhh]], [[4mhj]], [[6n5b]], [[6n5d]] - mFab anti-influenza virus hemagglutinin<br /> |
| + | **[[4qnp]], [[1nca]], [[1ncb]], [[1ncc]], [[1ncd]] – mFab + influenza neuraminidase<br /> | ||
| + | **[[6n5e]], [[7fah]] – mFab + influenza hemagglutinin <br /> | ||
| + | **[[6wzt]], [[7dkj]], [[7jix]], [[7yhk]] – mFab + influenza hemagglutinin – Cryo EM<br /> | ||
**[[1rvf]] – mFab 17-IA + intact rhinovirus<br /> | **[[1rvf]] – mFab 17-IA + intact rhinovirus<br /> | ||
**[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br /> | **[[3j3o]], [[3j3p]]- mFab + poliovirus proteins – cryoEM<br /> | ||
**[[6mui]], [[6mw9]], [[6mwc]], [[6mwv]], [[6mwx]] - mFab + equine encephalitis virus proteins – cryoEM<br /> | **[[6mui]], [[6mw9]], [[6mwc]], [[6mwv]], [[6mwx]] - mFab + equine encephalitis virus proteins – cryoEM<br /> | ||
| - | **[[ | + | **[[5kvg]], [[5kvf]], [[5kve]], [[5kvd]], [[5jhl]], [[6uta]] – mFab + zika envelope DIII <br /> |
| - | + | ||
| - | + | ||
**[[3ve0]] - mFab + Ebola envelope glycoprotein<br /> | **[[3ve0]] - mFab + Ebola envelope glycoprotein<br /> | ||
| - | **[[5y9t]], [[5y9c]], [[5y9f]] – mFab + papilloma virus capsid protein<br /> | + | **[[5y9t]], [[5y9c]], [[5y9f]], [[7ew5]] – mFab + papilloma virus capsid protein<br /> |
| - | **[[4l5f]] – mFab + dengue virus envelope protein <br /> | + | **[[4l5f]], [[6fla]], [[6flb]], [[6flc]] – mFab + dengue virus envelope protein <br /> |
| + | **[[5zud]], [[5zuf]], [[6aj7]], [[6aj9]] – mFab + enterovirus caspid proteins – Cryo EM<br /> | ||
| + | **[[3fmg]] – mFab + rotavirus glycoprotein VP7<br /> | ||
| + | **[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | ||
| + | **[[7ki6]] – mFab + Hendra virus F0 – Cryo EM<br /> | ||
| + | **[[7ki4]], [[7txz]], [[7ty0]] – mFab + nipah virus protein – Cryo EM<br /> | ||
| + | **[[7rfp]] – mFab + muromegalovirus GITR – Cryo EM<br /> | ||
| + | **[[7u9g]], [[8a1e]] – mFab + rabies virus glycoprotein – Cryo EM<br /> | ||
| + | **[[7kyl]] – mFab + deer tick virus glycoprotein <br /> | ||
| + | **[[7c80]], [[7c81]], [[7eaj]], [[7eak]], [[7cmk]] – mFab + echovirus glycoproteins – Cryo EM<br /> | ||
| + | **[[7m3l]], [[7m3m]], [[7m3n]] – mFab + parvovirus glycoproteins – Cryo EM<br /> | ||
| + | **[[7qu1]] – mFab + marchupovirus glycoproteins <br /> | ||
| + | **[[7qu2]] – mFab + mammarenavirus glycoproteins <br /> | ||
| + | **[[7dq7]] – mFab + coxsackievirus proteins – Cryo EM<br /> | ||
| - | *Anti-HIV Fab: protein complex | + | *Anti-HIV Fab: protein complex or broadly neutralizing antibody complex |
| - | **[[3mac]], [[3ma9]] | + | **[[3mac]], [[3ma9]], [[6fy1]] – hFab anti-HIV 8062 + transmembrane glycoprotein<br /> |
| - | + | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[6w4m]], [[6bck]], [[6bf4]], [[6d2p]], [[6db5]], [[6oej]], [[6ofi]], [[7klc]], [[7rdw]] - hFab anti-HIV + gp120 core<br /> | |
| - | **[[3idx]], [[3idy]], [[2ny7]], [[4jpw]], [[4lsp]], [[4lsq]], [[4lsr]], [[4lss]], [[4lst]], [[4lsu]], [[4lsv]], [[5te4]], [[5fyl]], [[5f9w]], [[5f96]], [[5f6j]], [[4ywg]], [[4ye4]], [[4ydl]], [[4ydk]], [[4ydj]], [[4ydi]], [[4yc2]], [[4ybl]], [[4s1s]], [[4s1r]], [[4s1q]], [[4rwy]], [[4rfn]], [[5w4l]], [[ | + | **[[6b0n]] - hFab anti-HIV + gp140<br /> |
**[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br /> | **[[5v7j]], [[4j6r]] - hFab anti-HIV + gp160<br /> | ||
| - | **[[4xnz]], [[4xny]], [[4xmp]] - hFab anti-HIV + gp41<br /> | + | **[[6dfg]], [[6dfh]], [[6e5p]], [[6pwu]] - hFab anti-HIV + gp160 – Cryo EM<br /> |
| + | **[[4xnz]], [[4xny]], [[4xmp]], [[7ekb]], [[7n05]], [[7n08]] - hFab anti-HIV + gp41<br /> | ||
| + | **[[7n65]] - hFab anti-HIV + gp41 – Cryo EM<br /> | ||
| + | **[[3lqa]], [[2qad]] - hFab anti-HIV + CD4 + gp41<br /> | ||
| + | **[[5jsa]], [[5js9]], [[5c7k]], [[5v8l]], [[5v8m]], [[6ccb]], [[6mft]], [[6orn]], [[6oro]], [[6orp]], [[6orq]], [[6utk]], [[6v6w]], [[7kmd]], [[7ucf]] - hFab anti-HIV + gp41 + gp120<br /> | ||
| + | **[[6nij]], [[6nqd]], [[6ulc]], [[6um5]], [[6um6]], [[6um7]], [[6vo3]], [[6vy2]], [[7kde]], [[7lg6]], [[7ll1]], [[7ll2]], [[7llk]], [[7pc2]], [[7rsn]], [[7rso]], [[7tfo]] - hFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
| + | **[[6opa]], [[6oz4]] - hFab anti-HIV + gp41 + gp160<br /> | ||
| + | **[[6ozc]], [[7sq1]] - hFab anti-HIV + gp41 + gp160 – Cryo EM<br /> | ||
| + | **[[6u0l]], [[6u0n]] - hFab anti-HIV + gp41 + gp160 + CD4 – Cryo EM<br /> | ||
| + | **[[4r4n]], [[4r4f]], [[6mg7]], [[6w4m]] - hFab anti-HIV + gp120 + M48U1<br /> | ||
| + | **[[7lok]] - hFab anti-HIV + gp120 + gp41 + M48U1 – Cryo EM<br /> | ||
| + | **[[6vpx]] - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM<br /> | ||
**[[5tfw]], [[5t85]], [[5t80]], [[5t6l]], [[5t5b]], [[5t29]] - hFab anti-HIV + T117V2<br /> | **[[5tfw]], [[5t85]], [[5t80]], [[5t6l]], [[5t5b]], [[5t29]] - hFab anti-HIV + T117V2<br /> | ||
**[[2x7l]] – hFab anti-HIV + HIV REV<br /> | **[[2x7l]] – hFab anti-HIV + HIV REV<br /> | ||
| - | **[[ | + | **[[6cdm]], [[6cdo]], [[6cdp]], [[6ch8]], [[6ch9]], [[6chb]], [[6ck9]], [[6cxg]], [[6fy2]], [[6muf]], [[6myy]], [[6mzj]], [[6w03]] – hFab anti-HIV + HIV protein<br /> |
| - | **[[ | + | **[[6cde]], [[6cdi]], [[6edu]], [[7n28]] – hFab anti-HIV + HIV protein – Cryo EM<br /> |
| + | **[[7lua]] – hFab anti-HIV + sHIV protein + gp120 – Cryo EM<br /> | ||
| + | **[[6uuh]] – hFab anti-HIV + IggG<br /> | ||
| + | **[[6mam]] – hFab anti-HIV + ebola glycoprotein<br /> | ||
| + | **[[6qd7]], [[6qd8]] – hFab anti-HIV + ebola glycoprotein – Cryo EM<br /> | ||
| + | **[[6id4]], [[7re7]] – hFab anti-HIV + MHC antigen + beta-2-microglobulin<br /> | ||
| + | **[[3bqu]] – hFab 2F5 anti-HIV + mFab 3H6<br /> | ||
| + | **[[6ce0]], [[6vlw]], [[6w16]], [[7mxd]] – hFab + HIV-1 protein<br /> | ||
| + | **[[7ly9]], [[7ucg]] – hFab + HIV-1 envelope protein – Cryo EM<br /> | ||
| + | **[[1g9m]], [[1g9n]], [[1gc1]], [[2i5y]], [[2i60]], [[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]], [[3jwd]], [[3jwo]], [[5a8h]], [[5a7x]], [[4r4h]], [[4h8w]] - hFab anti-HIV + envelope glycoprotein gp120 + CD4<br /> | ||
| + | **[[6mtj]], [[6mtn]], [[6mu6]], [[6mu7]], [[6mu8]], [[6mug]] - hFab anti-HIV + HIV proteins + inhibitor<br /> | ||
| + | **[[7l86]], [[7l87]], [[7l88]], [[7l89]], [[7l8a]], [[7l8b]], [[7l8c]], [[7l8d]], [[7l8f]], [[7l8g]], [[7l8s]], [[7l8t]], [[7l8u]], [[7l8w]], [[7l8x]], [[7l8y]], [[7l8z]], [[7l90]], [[7lu9]], [[7mxe]] - rmFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
| + | **[[7l8e]] - rmFab anti-HIV + gp160 – Cryo EM<br /> | ||
| + | **[[6vkn]], [[6vn0]], [[6xrt]], [[7tfn]] - rmFab anti-HIV + gp41 + gp160 – Cryo EM<br /> | ||
| + | **[[6vlr]], [[7n0x]], [[7n8q]] – rmFab anti-HIV + HIV protein<br /> | ||
| + | **[[6xcj]] - rmFab anti-HIV + gp120 core<br /> | ||
| + | **[[6pw6]], [[6vo1]] - bFab anti-HIV + gp41 + gp120 – Cryo EM<br /> | ||
**[[1afv]] – mFab anti-HIV + capsid protein C<br /> | **[[1afv]] – mFab anti-HIV + capsid protein C<br /> | ||
| - | **[[ | + | **[[6p8m]], [[7jks]], [[7jkt]] - mFab anti-HIV + gp120 core<br /> |
| + | **[[6cez]], [[6p65]], [[6vo0]] – rFab anti-HIV + HIV protein – Cryo EM<br /> | ||
| + | **[[5dhz]], [[5dhy]], [[5dhx]], [[5dhv]], [[6cbp]], [[6nnf]] – hscFv anti-HIV + HIV protein<br /> | ||
| + | **[[3rjq]], [[7r73]], [[7r74]], [[7ri1]], [[7ri2]] – LgVHH anti-HIV + gp120<br /> | ||
| + | **[[7lpn]] – LgVHH anti-HIV + gp160 + gp41<br /> | ||
| + | **[[2xt1]], [[2xxm]] – ViVHH anti-HIV + HIV capsid<br /> | ||
*Other Fab: protein complex | *Other Fab: protein complex | ||
| Line 306: | Line 574: | ||
**[[2r56]] – bFab igE + β-lactoglobulin <br /> | **[[2r56]] – bFab igE + β-lactoglobulin <br /> | ||
**[[1g6v]] – bFab + carbonic anhydrase<br /> | **[[1g6v]] – bFab + carbonic anhydrase<br /> | ||
| - | **[[ | + | **[[7eo0]], [[7fei]], [[7fej]] – bFab + FMD virus proteins – Cryo EM<br /> |
**[[4n9g]] - rmFab + scaffold<br /> | **[[4n9g]] - rmFab + scaffold<br /> | ||
| - | **[[ | + | **[[6xgc]] – rmFab + Influenza virus hemagglutinin – Cryo EM<br /> |
| - | **[[ | + | **[[7nks]], [[7nrh]], [[7o9s]] - rFab + hantavirus envelope polyprotein <br /> |
| + | **[[6z06]] - vFab + hantavirus envelope polyprotein – vole <br /> | ||
| + | **[[7b09]] - vFab + hantavirus envelope polyprotein – Cryo EM<br /> | ||
| + | **[[6oor]] – raFab + β-2-microglobulin + CD1D<br /> | ||
| + | **[[6e62]] – raFab + malaria protein<br /> | ||
| + | **[[6qig]] – raFab + ADAMTS-13<br /> | ||
| + | **[[6al0]], [[6al1]] – raFab + S2P<br /> | ||
| + | **[[7k22]], [[7k23]] – raFab + VP1 – Cryo EM<br /> | ||
| + | **[[7kq7]] – raFab + IL21R<br /> | ||
| + | **[[6gku]] – LgFab + galectin<br /> | ||
| + | **[[4hgk]] – Fab + albumin – shark<br /> | ||
| + | **[[6vi1]] – syFab + terminase<br /> | ||
| + | **[[6iap]] – syFab + Nkp46<br /> | ||
| + | **[[7mdj]] - syFab + KcsA K+ channel + ion<br /> | ||
| + | **[[7keo]] – syFab igG1 + ubiquitin<br /> | ||
| + | **[[6i8s]] - EcFab + plasminogen activator inhibitor – Escherichia coli<br /> | ||
| + | **[[6pis]] – Fab + TRAAK – Cricetulus migratorius<br /> | ||
| + | **[[7y7m]], [[7yms]], [[7yrf]], [[7yrh]] – Fab + coxsackievirus proteins – Cryo EM<br /> | ||
*Human Fab: protein higher complexes | *Human Fab: protein higher complexes | ||
| Line 322: | Line 607: | ||
**[[4mxw]] - hFab + TNFR-III + lymphotoxin<br /> | **[[4mxw]] - hFab + TNFR-III + lymphotoxin<br /> | ||
**[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | **[[3bt2]] – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin<br /> | ||
| - | **[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> | ||
| - | **[[6gv4]] – hFab + parechovirus proteins + RNA - Cryo EM<br /> | ||
**[[6cw2]] – hFab + histone acetyltransferase + transcriptional adapter<br /> | **[[6cw2]] – hFab + histone acetyltransferase + transcriptional adapter<br /> | ||
| - | **[[6c5v]] – hFab + herpesvirus proteins - Cryo EM<br /> | ||
**[[6c08]] – hFab + amino acid transporter + Arg<br /> | **[[6c08]] – hFab + amino acid transporter + Arg<br /> | ||
| - | + | **[[6apd]] – hFab + RSV fusion protein + immunoglobulin + IGL <br /> | |
| - | + | **[[6w51]] – hFab + 2-b-microglobulin + MHC + p53 peptide<br /> | |
| - | + | **[[7bbg]] – hFab + 2-b-microglobulin + MHC + wilms tumor peptide<br /> | |
| - | **[[ | + | **[[3gjf]], [[3hae]] – hFab + β-2-microglobulin + MHC antigen + NYESO peptide<br /> |
| - | **[[ | + | **[[7bh8]] – hFab + 2-b-microglobulin + MHC + VL9 peptide<br /> |
| - | **[[ | + | **[[6o1f]] - hFab + trypsin inhibitor + tryptase<br /> |
| - | **[[ | + | **[[7joo]] - hFab + LgVHH + ICOS<br /> |
| + | **[[6fn1]], [[7a65]], [[7a69]], [[7a6c]], [[7a6e]], [[7a6f]] – hFab + ABCB + drug<br /> | ||
| + | **[[6w9g]] - hFab + CD40 + fluorescent amino acid<br /> | ||
| + | **[[6ww2]] – hFab + syVHH + frizzled-5 – Cryo EM<br /> | ||
| + | **[[7tdm]], [[7tdn]] – hFab + claudin + enterotoxin – Cryo EM<br /> | ||
| + | **[[7mhy]] – hFab + HHAT + palmitoyl-CoA – Cryo EM<br /> | ||
| + | **[[7ncs]], [[7nd0]] – hFab in BAM complex – Cryo EM<br /> | ||
*Mouse Fab: protein higher complexes | *Mouse Fab: protein higher complexes | ||
| - | **[[3ixx]], [[3ixy]] - mFab E53 + envelope glycoprotein + West Nile virus peptide<br /> | ||
**[[5w3e]], [[5w3l]], [[5w3m]], [[5w3o]], [[5w3p]] - mFab C5 + Rhinovirus protein 1 + protein 2 + protein 3 + protein 4<br /> | **[[5w3e]], [[5w3l]], [[5w3m]], [[5w3o]], [[5w3p]] - mFab C5 + Rhinovirus protein 1 + protein 2 + protein 3 + protein 4<br /> | ||
**[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]], [[5vk6]], [[5vke]], [[5vkh]], [[6by2]], [[6by3]] - mFab + KcsA K+ channel + ion<br /> | **[[3gb7]], [[2p7t]], [[2h8p]], [[2hfe]], [[2atk]], [[4wfh]], [[4wfg]], [[4wff]], [[4wfe]], [[5vk6]], [[5vke]], [[5vkh]], [[6by2]], [[6by3]] - mFab + KcsA K+ channel + ion<br /> | ||
| Line 346: | Line 633: | ||
**[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br /> | **[[1qkz]] – mFab + protein G prime + major outer membrane protein peptide<br /> | ||
**[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br /> | **[[2ibz]] – mFab + cytochrome bc1 complex + stigmatellin <br /> | ||
| + | **[[6jmq]], [[6jmr]] – mFab + large neutral amino acid transporter + 4f2 cell-surface antigen<br /> | ||
| + | **[[6qno]] - mFab + guanine nucleotide-binding protein + transducin + rhodopsin – Cryo EM<br /> | ||
| + | **[[7k78]] - mFab + yeast nucleosome – Cryo EM<br /> | ||
| + | **[[7rxc]], [[7rxd]] - mFab + viVVH + ER lumen receptors – Cryo EM<br /> | ||
| + | **[[7c6a]] – mFab + angiotensin receptor + SAR1<br /> | ||
| + | **[[6gff]] – mFab + TGF + GARPIN<br /> | ||
| + | **[[7kpb]] – mFab + TNF + TNFR<br /> | ||
| + | **[[7df9]], [[7dfa]], [[7dfb]], [[7dfc]] – mFab + arrestin + arrestin receptor<br /> | ||
*Full Immunoglobulin | *Full Immunoglobulin | ||
| Line 352: | Line 647: | ||
**[[1iga]] - hIgA1 - model<br /> | **[[1iga]] - hIgA1 - model<br /> | ||
| - | *Fc Fragments | + | *Fc Fragments or immunoglobulin gamma-1 heavy chain |
| - | **[[3dnk]] - hFc | + | **[[3dnk]] - hFc Igg1<br /> |
**[[1qp1]] – hFc BRE<br /> | **[[1qp1]] – hFc BRE<br /> | ||
**[[3muh]] – hFc PG9<br /> | **[[3muh]] – hFc PG9<br /> | ||
| Line 360: | Line 655: | ||
**[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br /> | **[[1f6a]] - hFc IgE + high-affinity receptor Fc (ε) RI (α)<br /> | ||
**[[1fp5]] - hFc IgE C ε 3-C ε 4<br /> | **[[1fp5]] - hFc IgE C ε 3-C ε 4<br /> | ||
| + | **[[6cjx]], [[6f2z]], [[6x3i]] - hFc (mutant) <br /> | ||
| + | **[[6iqg]], [[7mfr]] - hFc + peptide<br /> | ||
| + | **[[6d4i]] - rmFc Igg2<br /> | ||
| + | **[[6d4e]], [[6d4m]] - rmFc Igg3<br /> | ||
| + | **[[6d4n]] - rmFc Igg4<br /> | ||
*Fv Fragments | *Fv Fragments | ||
| + | **[[3zhd]], [[3zhk]], [[3zhl]] – hFv scaffold<br /> | ||
| + | **[[4u3x]] – hFv + lysozyme<br /> | ||
**[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br /> | **[[3dur]], [[3dus]], [[3duu]], [[3dv4]], [[3dv6]] – mFv + Ig-like protein<br /> | ||
**[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br /> | **[[3hb3]] – mFv + cytochrome c oxidase subunit 1-β<br /> | ||
**[[1qle]] - mFv + cytochrome c oxidase<br /> | **[[1qle]] - mFv + cytochrome c oxidase<br /> | ||
| - | **[[ | + | **[[6oik]] - mFv + AChR + guanine nucleotide-binding protein + transducin – Cryo EM<br /> |
| - | + | ||
* Single chain variable fragment (scFv) | * Single chain variable fragment (scFv) | ||
| - | **[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]] – hscFv <br /> | + | **[[6ehy]], [[6ehv]], [[6ehw]], [[6ehx]], [[5c2b]], [[5wym]], [[1x9q]], [[2a9m]], [[3kdm]], [[4buh]], [[3u6r]], [[3auv]], [[6qb9]], [[6qf9]], [[6vrp]], [[7ah1]] – hscFv <br /> |
| - | **[[4x4x]], [[6dn0]], [[2a9n]] – hscFv (mutant)<br /> | + | **[[4x4x]], [[6dn0]], [[2a9n]], [[6vun]], [[6vuo]], [[6vup]], [[7kbm]], [[7kbo]], [[7kpb]] – hscFv (mutant)<br /> |
| - | **[[ | + | **[[6ffj]] – hscFv anti-tumor<br /> |
| - | **[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]] – mscFv <br /> | + | **[[6uup]], [[6uy3]] – cscFv - camel <br /> |
| + | **[[6pil]], [[6psc]] – rscFv <br /> | ||
| + | **[[1h8n]], [[1lmk]], [[1nqb]],[[4h0g]], [[4nkd]], [[4nkm]], [[4nko]], [[3nn8]], [[3bd3]], [[3bd4]], [[3bd5]], [[2gjj]], [[5b3n]], [[4laq]], [[4gqp]], [[3umt]], [[6s2i]], [[6tnp]], [[7aql]], [[7eq3]] – mscFv <br /> | ||
**[[1p4i]] – mscFv (mutant)<br /> | **[[1p4i]] – mscFv (mutant)<br /> | ||
**[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br /> | **[[4p49]], [[4p48]], [[4ouo]], [[5vf6]] – scFv - chicken<br /> | ||
| + | **[[6wzn]] – syscFv <br /> | ||
* Single chain variable fragment complex | * Single chain variable fragment complex | ||
| - | **[[5lbs]] – hscFv + envelope protein E<br /> | + | **[[5lbs]] – hscFv + zika envelope protein E<br /> |
**[[5ljy]] – hscFv + Hantaan virus envelope protein<br /> | **[[5ljy]] – hscFv + Hantaan virus envelope protein<br /> | ||
| - | **[[ | + | **[[6pcu]] – hscFv + rotavirus capsid protein<br /> |
| + | **[[7cth]] – hscFv + dengue protein – Cryo EM<br /> | ||
**[[4nik]] – hscFv + gankyrin<br /> | **[[4nik]] – hscFv + gankyrin<br /> | ||
**[[5jz7]] – hscFv + NGF<br /> | **[[5jz7]] – hscFv + NGF<br /> | ||
**[[4kv5]] – hscFv + TGF<br /> | **[[4kv5]] – hscFv + TGF<br /> | ||
| + | **[[5iwl]] – hscFv + CD47<br /> | ||
| + | **[[6tou]] – hscFv + rabies glycoprotein<br /> | ||
| + | **[[6ikm]] – hscFv + polyamine transport protein<br /> | ||
**[[2ybr]], [[2yc1]] – hscFv + CN2 toxin<br /> | **[[2ybr]], [[2yc1]] – hscFv + CN2 toxin<br /> | ||
**[[5ujz]], [[5uk0]], [[5uk1]], [[5uk2]] - hscFv + hemagglutinin – Cryo EM<br /> | **[[5ujz]], [[5uk0]], [[5uk1]], [[5uk2]] - hscFv + hemagglutinin – Cryo EM<br /> | ||
**[[4v1d]] - hscFv + mammal toxin CN2 <br /> | **[[4v1d]] - hscFv + mammal toxin CN2 <br /> | ||
| - | **[[ | + | **[[6i07]] – hscFv + EpCAM<br /> |
| + | **[[6kn9]] – hscFv + IL-18R<br /> | ||
| + | **[[5d9q]] – hscFv + antibody + gp120 + gp40<br /> | ||
| + | **[[7jum]] – hscFv + P230<br /> | ||
| + | **[[7tzg]], [[7tzh]] – hscFv + LAG3<br /> | ||
| + | **[[7xw7]] – hscFv + thyrotropin receptor – Cryo EM<br /> | ||
| + | **[[6e0c]], [[6e0p]] - hscFv in nucleosome – Cryo EM<br /> | ||
| + | **[[8dpf]], [[8dpg]], [[8dph]], [[8dpi]] – hscFv + Gi + 5HT2C receptor + drug – Cryo EM<br /> | ||
| + | **[[7jvr]] – hscFv + Gi + dopamine receptor + drug – Cryo EM<br /> | ||
| + | **[[7tuz]] – hscFv + Gi + GPR183 + drug – Cryo EM<br /> | ||
| + | **[[7d3k]], [[7d3l]], [[7d3m]], [[7d3r]] – bscFv + FMDV proteins – Cryo EM<br /> | ||
**[[3ab0]] – mscFv + BCLA protein<br /> | **[[3ab0]] – mscFv + BCLA protein<br /> | ||
**[[5jyl]], [[5jym]] – mscFv + cadherin<br /> | **[[5jyl]], [[5jym]] – mscFv + cadherin<br /> | ||
| Line 399: | Line 717: | ||
**[[5ogi]] – mscFv + hexon protein <br /> | **[[5ogi]] – mscFv + hexon protein <br /> | ||
**[[3h3b]], [[6eqc]] – mscFv + hexon protein – Cryo EM<br /> | **[[3h3b]], [[6eqc]] – mscFv + hexon protein – Cryo EM<br /> | ||
| + | **[[7rkf]], [[7rkm]], [[7rkn]], [[7rkx]], [[7rky]] – mscFv + Gi + US27 – Cryo EM<br /> | ||
| + | **[[7xmt]] – mscFv + Gi + SSTR4 – Cryo EM<br /> | ||
| + | **[[7jhj]] – mscFv + Gi + BILF1 – Cryo EM<br /> | ||
**[[4f9p]], [[4f9l]] – mscFv + BTN3A1<br /> | **[[4f9p]], [[4f9l]] – mscFv + BTN3A1<br /> | ||
| - | **[[5aam]], [[5aaw]] – mscFv + Dengue virus envelope protein<br /> | + | **[[5aam]], [[5aaw]], [[7k93]] – mscFv + Dengue virus envelope protein<br /> |
**[[5kov]] – mscFv + Astrovirus envelope protein<br /> | **[[5kov]] – mscFv + Astrovirus envelope protein<br /> | ||
| + | **[[7rk1]] – mscFv + Astrovirus VP70<br /> | ||
| + | **[[7rk2]] – mscFv + Astrovirus VP25<br /> | ||
| + | **[[6h3t]], [[6h3u]] – mscFv + bovine schmallenberg virus envelope protein<br /> | ||
**[[1dzb]], [[2znx]] – mscFv + lysozyme<br /> | **[[1dzb]], [[2znx]] – mscFv + lysozyme<br /> | ||
**[[1a14]], [[1nmc]] – mscFv + neuraminidase<br /> | **[[1a14]], [[1nmc]] – mscFv + neuraminidase<br /> | ||
| + | **[[5gs2]] – mscFv + MBP + repebody<br /> | ||
**[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br /> | **[[1fo0]], [[1kj2]], [[1nam]] – mscFv + TCR + MHC + peptide<br /> | ||
| - | **[[ | + | **[[7k5x]], [[7k5y]], [[7k60]], [[7k61]], [[7k63]] - mscFv + human nucleosome – Cryo EM<br /> |
| + | **[[6lgw]] – rmscFv + rabies glycoprotein<br /> | ||
* Single chain variable fragment complex with small molecule | * Single chain variable fragment complex with small molecule | ||
| Line 416: | Line 742: | ||
**[[4lar]] – hscFv + dexedrine<br /> | **[[4lar]] – hscFv + dexedrine<br /> | ||
**[[4las]] – hscFv + amphetamine derivative<br /> | **[[4las]] – hscFv + amphetamine derivative<br /> | ||
| + | **[[6k4z]] – mscFv + NPA<br /> | ||
* Single chain variable fragment complex with peptide | * Single chain variable fragment complex with peptide | ||
**[[5yax]] – hscFv + HBV peptide<br /> | **[[5yax]] – hscFv + HBV peptide<br /> | ||
| - | **[[5npi]], [[5npj]] – mscFv + hepatitis peptide<br /> | ||
**[[5a2i]], [[5aij]], [[5a2k]], [[5a2l]] – mscFv + TN peptide<br /> | **[[5a2i]], [[5aij]], [[5a2k]], [[5a2l]] – mscFv + TN peptide<br /> | ||
**[[1p4b]] – mscFv + GCN4 peptide<br /> | **[[1p4b]] – mscFv + GCN4 peptide<br /> | ||
| - | **[[4h0h]], [[5fxc]], [[5owp]], [[1ktr]] – mscFv + peptide<br /> | + | **[[4h0h]], [[5fxc]], [[5owp]], [[1ktr]], [[6fzq]], [[6tgg]] – mscFv + peptide<br /> |
| - | *Single domain antibody VHH or Camelid antibody or nanobody | + | *Single domain antibody VHH or Camelid antibody or nanobody or single domain antibody or sybody |
**[[5i0z]], [[5c6w]] – hVHH <br /> | **[[5i0z]], [[5c6w]] – hVHH <br /> | ||
**[[6cnw]] – hyVHH - hybrid<br /> | **[[6cnw]] – hyVHH - hybrid<br /> | ||
| - | **[[4ppt]], [[4idl]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[6ezw]], [[6f0d]], [[5nlu]], [[4krn]], [[4poy]], [[1sjv]], [[1u0q]], [[3qxu]], [[3qxw]], [[4b50]], [[5tp3]], [[1sjx]], [[4qgy]], [[5h8d]], [[4b5e]], [[6fys]] – LgVHH <br /> | + | **[[4ppt]], [[4idl]], [[1shm]], [[2xa3]], [[5sv4]], [[4w81]], [[4w70]], [[4w68]], [[4tyu]], [[6ezw]], [[6f0d]], [[5nlu]], [[4krn]], [[4poy]], [[1sjv]], [[1u0q]], [[3qxu]], [[3qxw]], [[4b50]], [[5tp3]], [[1sjx]], [[4qgy]], [[5h8d]], [[4b5e]], [[6dbd]], [[6fpv]], [[6fys]], [[6oc8]], [[6ru3]], [[7lvu]] – LgVHH <br /> |
| - | **[[1g9e]] – LgVHH - NMR<br /> | + | **[[1g9e]], [[7eh3]] – LgVHH - NMR<br /> |
**[[4u05]] – LgVHH (mutant)<br /> | **[[4u05]] – LgVHH (mutant)<br /> | ||
| - | **[[4w2p]], [[6apo]], [[6apq]] – LgVHH anti-marburg virus<br /> | + | **[[4w2p]], [[6apo]], [[6app]], [[6apq]] – LgVHH anti-marburg virus<br /> |
**[[6ck8]] – LgVHH anti-influenza virus<br /> | **[[6ck8]] – LgVHH anti-influenza virus<br /> | ||
| - | **[[3r0m]] – LgVHH anti-HIV<br /> | ||
| - | **[[2xxc]] – ViVHH anti-HIV - vicuna<br /> | ||
**[[6cwk]] – ViVHH anti-ricin<br /> | **[[6cwk]] – ViVHH anti-ricin<br /> | ||
| - | **[[5u64]], [[5u65]], [[1f2x]], [[1yc7]], [[5e7b]], [[5m7q]], [[5jmr]], [[3dwt]], [[3tpk]], [[3ln9]] – cVHH | + | **[[6dyx]], [[6iyn]] – ViVHH <br /> |
| + | **[[5u64]], [[5u65]], [[1f2x]], [[1yc7]], [[5e7b]], [[5m7q]], [[5jmr]], [[3dwt]], [[3tpk]], [[3ln9]], [[6heq]], [[6jb9]], [[6qtl]] – cVHH <br /> | ||
**[[1yc8]], [[3eak]] – cVHH (mutant)<br /> | **[[1yc8]], [[3eak]] – cVHH (mutant)<br /> | ||
| + | **[[6itp]], [[6itq]] – cVHH anti-cortisol<br /> | ||
| + | **[[6t2j]], [[7mfv]] – syVHH <br /> | ||
| + | **[[7v0v]] – syVHH anti-GFP - NMR<br /> | ||
*VHH binary complexes | *VHH binary complexes | ||
| + | **[[6oan]], [[6oao]] – hVHH + DBP<br /> | ||
| + | **[[6sge]] – hVHH + ROHB<br /> | ||
| + | **[[7ssz]] - hVHH + Kv1.3 – Cryo EM<br /> | ||
**[[1i3u]], [[1i3v]], [[1dq0]] - LgVHH + hapten<br /> | **[[1i3u]], [[1i3v]], [[1dq0]] - LgVHH + hapten<br /> | ||
**[[3qxt]], [[3qxv]] – LgVHH + methotrexate<br /> | **[[3qxt]], [[3qxv]] – LgVHH + methotrexate<br /> | ||
| Line 448: | Line 779: | ||
**[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]], [[3k7u]], [[3k80]] – LgVHH + RNA editing complex protein<br /> | **[[3k81]], [[3stb]], [[4dk3]], [[4dk6]], [[4dka]], [[3k7u]], [[3k80]] – LgVHH + RNA editing complex protein<br /> | ||
**[[5tok]], [[5toj]] – LgVHH + F glycoprotein<br /> | **[[5tok]], [[5toj]] – LgVHH + F glycoprotein<br /> | ||
| - | **[[5boz]], [[5j57]], [[5j56]], [[5e1h]], [[5sv3]] – LgVHH + ricin<br /> | + | **[[5boz]], [[5j57]], [[5j56]], [[5e1h]], [[5sv3]], [[7kbi]], [[7kbk]], [[7kc9]], [[7kd0]], [[7kd2]], [[7kdm]], [[7kdu]] – LgVHH + ricin<br /> |
**[[5hm1]] – LgVHH + gp41<br /> | **[[5hm1]] – LgVHH + gp41<br /> | ||
**[[5o2u]] – LgVHH + p24<br /> | **[[5o2u]] – LgVHH + p24<br /> | ||
| Line 455: | Line 786: | ||
**[[4hep]], [[4hem]] – LgVHH + BPP<br /> | **[[4hep]], [[4hem]] – LgVHH + BPP<br /> | ||
**[[4w2q]], [[4w2o]], [[6app]] – LgVHH + Marburg virus nucleoprotein<br /> | **[[4w2q]], [[4w2o]], [[6app]] – LgVHH + Marburg virus nucleoprotein<br /> | ||
| - | **[[6fyt]], [[6fyu]], [[6fyw]] – LgVHH + Influenza virus | + | **[[6fyt]], [[6fyu]], [[6fyw]], [[6s0y]] – LgVHH + Influenza virus protein<br /> |
| - | **[[6ana]], [[6and]], [[6ani]] – LgVHH + | + | **[[6qx3]] – LgVHH + Influenza virus protein – Cryo EM<br /> |
| + | **[[7dst]] – LgVHH + FMDV proteins – Cryo EM<br /> | ||
| + | **[[7jkm]] – LgVHH + hFab<br /> | ||
| + | **[[6ana]], [[6and]], [[6ani]] – LgVHH + mFab<br /> | ||
**[[4krl]], [[4krm]] – LgVHH + EGFR<br /> | **[[4krl]], [[4krm]] – LgVHH + EGFR<br /> | ||
| - | **[[3rjq]] – LgVHH anti-HIV + gp120<br /> | ||
**[[2bse]] – LgVHH + receptor-binding protein<br /> | **[[2bse]] – LgVHH + receptor-binding protein<br /> | ||
**[[4ej1]], [[4eiz]], [[4eig]] – LgVHH + DHFR <br /> | **[[4ej1]], [[4eiz]], [[4eig]] – LgVHH + DHFR <br /> | ||
| - | **[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]] – LgVHH + adrenergic receptor<br /> | + | **[[3p0g]], [[4lde]], [[4ldl]], [[4ldo]], [[6mxt]], [[7bu7]] – LgVHH + adrenergic receptor<br /> |
**[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br /> | **[[4n1h]], [[4m3k]], [[5lwf]] – LgVHH + beta-lactamase<br /> | ||
| - | ** | + | **[[5m94]], [[5m95]] – LgVHH + metal cation transporter<br /> |
| - | **[[5h8o]] – LgVHH + ASC<br /> | + | **[[5h8o]], [[6f2g]] – LgVHH + ASC<br /> |
**[[3k3q]] – LgVHH + Botox<br /> | **[[3k3q]] – LgVHH + Botox<br /> | ||
**[[4wem]], [[4wen]], [[4weu]] – LgVHH + adhesin<br /> | **[[4wem]], [[4wen]], [[4weu]] – LgVHH + adhesin<br /> | ||
**[[4p2c]] – LgVHH + Shiga toxin<br /> | **[[4p2c]] – LgVHH + Shiga toxin<br /> | ||
| + | **[[6oq5]], [[6oq6]], [[6oq7]], [[6oq8]] – LgVHH + Clostridium toxin<br /> | ||
| + | **[[6hjx]], [[6ssi]] – LgVHH + ELIC<br /> | ||
**[[4aq1]] – LgVHH + SBSB<br /> | **[[4aq1]] – LgVHH + SBSB<br /> | ||
**[[6h7j]], [[6h7l]], [[6h7m]], [[6h7n]] – lgVHH + thioredoxin + adrenergic receptor <br /> | **[[6h7j]], [[6h7l]], [[6h7m]], [[6h7n]] – lgVHH + thioredoxin + adrenergic receptor <br /> | ||
| - | **[[ | + | **[[6u51]], [[6u52]], [[6u54]], [[6u55]] – LgVHH anti-ebola + nucleoprotein<br /> |
| - | **[[ | + | **[[7lvw]] – LgVHH + RSV fusion protein<br /> |
| - | **[[ | + | **[[6qup]] – LgVHH + receptor kinase<br /> |
| - | **[[ | + | **[[6qgy]] – LgVHH + BamA<br /> |
| + | **[[6rvc]] – LgVHH + PTCH1<br /> | ||
| + | **[[6z6v]] – LgVHH + complement C1<br /> | ||
| + | **[[7qiv]] – LgVHH + complement C3b<br /> | ||
| + | **[[6h15]] – LgVHH + LRP6<br /> | ||
| + | **[[6b73]] – LgVHH + opioid receptor<br /> | ||
| + | **[[6i8g]] – LgVHH + EDS1<br /> | ||
| + | **[[6hhu]] – LgVHH + SAP<br /> | ||
| + | **[[6c9w]] – LgVHH + lactose permease<br /> | ||
| + | **[[6h02]] – LgVHH + mediator of RNA polymerase<br /> | ||
| + | **[[6gs4]] – LgVHH + DtpA<br /> | ||
| + | **[[6z1v]] – LgVHH + CD9<br /> | ||
| + | **[[7anq]] - LgVHH + PCSK9 <br /> | ||
| + | **[[7d4b]] - LgVHH + TNFRSF9 <br /> | ||
| + | **[[7nmu]] - LgVHH + platelet glycoprotein<br /> | ||
| + | **[[7a6o]] - LgVHH + von willenbrand factor <br /> | ||
| + | **[[7a48]], [[7a4d]], [[7a4t]], [[7a4y]], [[7a50]] - LgVHH + coiled-coil <br /> | ||
| + | **[[7qcq]] - LgVHH + Tau peptide <br /> | ||
| + | **[[7jjo]] - LgVHH + Gi proteins + transducin + adrenergic receptor<br /> | ||
| + | **[[7sai]] – LgVHH + GFP<br /> | ||
| + | **[[7a17]] – LgVHH + synaptojanin<br /> | ||
| + | **[[7ckz]] – LgVHH + Gi proteins + dopamine receptor – Cryo EM<br /> | ||
**[[4tvs]] – viVHH + LAP1<br /> | **[[4tvs]] – viVHH + LAP1<br /> | ||
**[[4yga]] – ViVHH + CDPK1<br /> | **[[4yga]] – ViVHH + CDPK1<br /> | ||
**[[5l21]] – ViVHH + Botox<br /> | **[[5l21]] – ViVHH + Botox<br /> | ||
| - | + | **[[5o04]], [[5o02]], [[5o03]], [[5o05]], [[5tjw]], [[5omn]], [[4x7c]], [[4x7d]], [[4x7e]], [[4x7f]], [[5m30]], [[6h6y]], [[6h71]], [[6h72]], [[6xw4]], [[6xw5]], [[6xw6]] – ViVHH + virus capsid<br /> | |
| - | **[[5o04]], [[5o02]], [[5o03]], [[5o05]], [[5tjw]], [[5omn]], [[4x7c]], [[4x7d]], [[4x7e]], [[4x7f]], [[5m30]] – ViVHH + virus capsid<br /> | + | |
**[[2xv6]] – ViVHH + p24<br /> | **[[2xv6]] – ViVHH + p24<br /> | ||
**[[5hvf]], [[5hvg]], [[5hvh]] – ViVHH + carboxypeptidase<br /> | **[[5hvf]], [[5hvg]], [[5hvh]] – ViVHH + carboxypeptidase<br /> | ||
**[[5hgg]], [[5lhr]], [[5lhq]], [[5lhp]], [[5lhn]] – ViVHH + urokinase-type plasminogen activator <br /> | **[[5hgg]], [[5lhr]], [[5lhq]], [[5lhp]], [[5lhn]] – ViVHH + urokinase-type plasminogen activator <br /> | ||
| + | **[[6gwn]], [[6gwp]], [[7aqg]] – ViVHH + plasminogen activator inhibitor<br /> | ||
**[[5vxm]], [[5vxj]], [[5vxk]], [[5vxl]], [[5vlj]] - ViVHH + invasion IpaD<br /> | **[[5vxm]], [[5vxj]], [[5vxk]], [[5vxl]], [[5vlj]] - ViVHH + invasion IpaD<br /> | ||
| - | **[[5u4l]], [[4z9k]], [[4lhj]], [[4lgp]], [[6cwg]], [[5u4m]] | + | **[[5u4l]], [[4z9k]], [[4lhj]], [[4lgp]], [[6cwg]], [[5u4m]], [[6obc]], [[6obe]], [[6obg]], [[6obm]], [[6obo]], [[6oca]], [[6ocd]] – ViVHH anti-ricin + ricin<br /> |
| + | **[[6x06]], [[6x07]], [[6x08]], [[7nqa]] – ViVHH + nucleoporin<br /> | ||
| + | **[[6rah]], [[6rai]] – ViVHH + TmrAB<br /> | ||
| + | **[[7k7y]], [[7lzp]] – ViVHH + botulinum neurotoxin<br /> | ||
| + | **[[1jto]], [[1jtp]], [[1jtt]], [[1ri8]], [[1xfp]], [[1zmy]], [[1zv5]], [[1zvh]], [[4i0c]], [[1op9]], [[1mel]], [[1rjc]], [[1zvy]], [[6jb8]] – cVHH + lysozyme<br /> | ||
| + | **[[6jb2]], [[6jb5]] – cVHH (mutant) + lysozyme<br /> | ||
| + | **[[2x89]] – cVHH + β-2-microglobulin<br /> | ||
| + | **[[1kxq]], [[1kxt]], [[1kxv]] – cVHH + α-amylase<br /> | ||
| + | **[[3qsk]], [[2p42]], [[2p43]], [[2p44]], [[2p45]], [[2p46]], [[2p47]], [[2p48]], [[2p49]], [[2p4a]] – cVHH + RNAse 1<br /> | ||
| + | **[[6ir1]], [[6ir2]], [[7sal]] – cVHH + mCherry<br /> | ||
| + | **[[6lr7]] – cVHH + GFP<br /> | ||
| + | **[[6rpj]] – cVHH + CTLA<br /> | ||
| + | **[[6hhd]] – cVHH + major prion protein<br /> | ||
| + | **[[6knm]] - cVHH + apelin receptor<br /> | ||
| + | **[[6sc5]], [[6sc6]], [[6sc7]], [[6sc8]], [[6sc9]] – syVHH + RNF31<br/> | ||
| + | **[[7cz0]] – syVHH + TGP<br/> | ||
*VHH ternary complexes | *VHH ternary complexes | ||
| Line 489: | Line 860: | ||
**[[3v0a]] – LgVHH + BONT/A1 + NTNH<br /> | **[[3v0a]] – LgVHH + BONT/A1 + NTNH<br /> | ||
**[[3sn6]] – LgVHH + adrenergic receptor + guanine nucleotide-binding protein<br /> | **[[3sn6]] – LgVHH + adrenergic receptor + guanine nucleotide-binding protein<br /> | ||
| + | **[[7bts]], [[7bu6]] – LgVHH + adrenergic receptor + epinephrine<br /> | ||
| + | **[[6oya]] - LgVHH + guanine nucleotide-binding protein + transducin + rhodopsin + GT-alpha/GI1-alpha – Cryo EM<br /> | ||
**[[4laj]] - LgVHH + envelope glycoprotein gp120 + CD4<br /> | **[[4laj]] - LgVHH + envelope glycoprotein gp120 + CD4<br /> | ||
**[[4orz]] – LgVHH + tyrosine protein kinase HCK + NEF<br /> | **[[4orz]] – LgVHH + tyrosine protein kinase HCK + NEF<br /> | ||
| + | **[[6v7z]] – LgVHH + CD1d + b-2-microglobulin<br /> | ||
| + | **[[6v80]] – LgVHH + CD1d + NKT TCR + b-2-microglobulin<br /> | ||
**[[4kro]], [[4krp]] – LgVHH + antibody + EGFR<br /> | **[[4kro]], [[4krp]] – LgVHH + antibody + EGFR<br /> | ||
| + | **[[7q6c]] – LgVHH + complement C1 + antibody<br /> | ||
**[[5j1s]], [[5j1t]] – ViVHH + Torsin + LULL1<br /> | **[[5j1s]], [[5j1t]] – ViVHH + Torsin + LULL1<br /> | ||
**[[5uk4]], [[5ukb]] – ViVHH + virus capsid + RNA<br /> | **[[5uk4]], [[5ukb]] – ViVHH + virus capsid + RNA<br /> | ||
**[[5jmo]] – cVHH + furin + CMK inhibitor<br /> | **[[5jmo]] – cVHH + furin + CMK inhibitor<br /> | ||
| - | **[[5fuc]] – cVHH + IL-6 + IL- | + | **[[5fuc]] – cVHH + IL-6 + IL-6R <br /> |
| + | **[[6h7j]], [[6h7l]], [[6h7m]], [[6h7o]], [[6ibl]] – cVHH + thioredoxin + adrenergic receptor<br /> | ||
| + | **[[6n48]] – cVHH + modulator + adrenergic receptor<br /> | ||
| + | **[[6do1]] – syVHH + BRIL + S1I8 peptide<br/> | ||
| - | * | + | *Intrabody or anti-helix antibody |
| - | **[[ | + | **[[6k67]] – hIB 3LRH + calmodulin<br /> |
| - | + | **[[6k3m]], [[6k64]], [[6k6a]], [[6k6b]] – hIB 3LRH + SpA IgG-binding domain protein<br /> | |
| + | **[[6k69]] – hIB 3LRH + T4 lysozyme<br /> | ||
| + | *Diabody or single chain Fv | ||
| + | **[[5fcs]], [[5grv]], [[5grw]], [[5grx]], [[5gry]], [[5grz]], [[5gs1]] – hDiab<br /> | ||
| + | **[[4y5v]], [[4y5x]], [[4y5y]] – hDiab + EpoR<br /> | ||
| + | **[[5gru]] – hDiab + MBP<br /> | ||
| + | **[[5gs0]] – hDiab + TLR3<br /> | ||
| + | **[[6vug]] – hDiab + Hiv reverse transcriptase + DNA<br /> | ||
| - | [[Category:Topic Page]] | + | *Antibody VH domain (residues 1-121) |
| + | |||
| + | **[[1t2j]], [[3b9v]], [[3qyc]], [[7omn]], [[7ooi]] – hVH <br /> | ||
| + | **[[1vhp]] – hVH - NMR<br /> | ||
| + | **[[7d6y]], [[7d8b]], [[7f07]], [[7xtp]] – hVH + EIF4E<br /> | ||
| + | **[[4u3x]] – hVH + lysozyme<br /> | ||
| + | **[[7dv4]] – hVH + CTLA-4<br /> | ||
| + | **[[5fv2]] – hVH + VEGF<br /> | ||
| + | **[[8di5]] – hVH + SARS spike glycoprotein – Cryo EM<br /> | ||
| + | **[[1nqb]] – mVH <br /> | ||
| + | **[[4qgy]], [[4qlr]] – LgVH <br /> | ||
| + | |||
| + | }} | ||
| + | [[Category: Topic Page]] | ||
Current revision
Humanized mouse antibody (hmFab) is a modified mFab which resembles more hFab.
Broadly neutralizing Fab and Neutralizing Fab are anti-HIV Fab.
Lama antibodies or nanobodies or camelid or VHH are natural single-domain antibodies containing just the heavy chain.
scFv is a single chain variable fragment in a fusion protein of the variable regions of the heavy and light chains of immunoglobulin.
3D structures of Antibody
Updated on 11-March-2023
