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5rjl
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5rjl is ON HOLD Authors: Grosjean, H., Aimon, A., Krojer, T., Talon, R., Douangamath, A., Koekemoer, L., Arrowsmith, C.H., Edwards, A., Bountra, C.,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024662== | |
| + | <StructureSection load='5rjl' size='340' side='right'caption='[[5rjl]], [[Resolution|resolution]] 1.31Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5rjl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RJL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UUG:(4-bromo-2-methoxyphenyl)methanol'>UUG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rjl OCA], [https://pdbe.org/5rjl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rjl RCSB], [https://www.ebi.ac.uk/pdbsum/5rjl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rjl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Aimon | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Biggin | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Aimon A]] |
| - | [[Category: Edwards | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Biggin PC]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Douangamath A]] |
| - | [[Category: | + | [[Category: Edwards A]] |
| - | [[Category: | + | [[Category: Grosjean H]] |
| + | [[Category: Koekemoer L]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00024662
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Categories: Homo sapiens | Large Structures | Aimon A | Arrowsmith CH | Biggin PC | Bountra C | Douangamath A | Edwards A | Grosjean H | Koekemoer L | Krojer T | Talon R | Von Delft F
