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5qyb

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Current revision (11:29, 21 February 2024) (edit) (undo)
 
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==PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a==
==PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a==
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<StructureSection load='5qyb' size='340' side='right'caption='[[5qyb]]' scene=''>
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<StructureSection load='5qyb' size='340' side='right'caption='[[5qyb]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5QYB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5qyb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QYB FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5qyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyb OCA], [http://pdbe.org/5qyb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qyb RCSB], [http://www.ebi.ac.uk/pdbsum/5qyb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyb ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R9G:(3-methoxyphenyl)(pyrrolidin-1-yl)methanone'>R9G</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyb OCA], [https://pdbe.org/5qyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qyb RCSB], [https://www.ebi.ac.uk/pdbsum/5qyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyb ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
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==See Also==
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*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Barthel T]]
[[Category: Barthel T]]
[[Category: Heine A]]
[[Category: Heine A]]

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PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D06a

PDB ID 5qyb

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