6vrb
From Proteopedia
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==Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex== | ==Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex== | ||
| - | <StructureSection load='6vrb' size='340' side='right'caption='[[6vrb]]' scene=''> | + | <StructureSection load='6vrb' size='340' side='right'caption='[[6vrb]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VRB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6vrb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_seeligeri Listeria seeligeri] and [https://en.wikipedia.org/wiki/Listeria_seeligeri_serovar_1/2b_str._SLCC3954 Listeria seeligeri serovar 1/2b str. SLCC3954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VRB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vrb OCA], [https://pdbe.org/6vrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vrb RCSB], [https://www.ebi.ac.uk/pdbsum/6vrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vrb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CS13A_LISSS CS13A_LISSS] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. Unlike many single-component effectors, this CRISPR-Cas system targets RNA (By similarity). CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:27669025).[UniProtKB:P0DOC6]<ref>PMID:27669025</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Listeria seeligeri]] | ||
| + | [[Category: Listeria seeligeri serovar 1/2b str. SLCC3954]] | ||
[[Category: Jia N]] | [[Category: Jia N]] | ||
[[Category: Marraffini LA]] | [[Category: Marraffini LA]] | ||
[[Category: Meeske AJ]] | [[Category: Meeske AJ]] | ||
[[Category: Patel DJ]] | [[Category: Patel DJ]] | ||
Current revision
Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex
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