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6wn6

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==Crystal structure of 3-keto-D-glucoside 4-epimerase, YcjR, from E. coli, apo form==
==Crystal structure of 3-keto-D-glucoside 4-epimerase, YcjR, from E. coli, apo form==
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<StructureSection load='6wn6' size='340' side='right'caption='[[6wn6]]' scene=''>
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<StructureSection load='6wn6' size='340' side='right'caption='[[6wn6]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WN6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WN6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6wn6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WN6 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wn6 OCA], [http://pdbe.org/6wn6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wn6 RCSB], [http://www.ebi.ac.uk/pdbsum/6wn6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wn6 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wn6 OCA], [https://pdbe.org/6wn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wn6 RCSB], [https://www.ebi.ac.uk/pdbsum/6wn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wn6 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YCJR_ECOLI YCJR_ECOLI] Catalyzes the epimerization at C4 of 3-dehydro-D-gulosides leading to 3-dehydro-D-glucosides. Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides. Can use methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro. However, the actual specific physiological substrates for this metabolic pathway are unknown. Cannot act on D-psicose, D-fructose, D-tagatose, D-sorbose, L-xylulose, or L-ribulose.<ref>PMID:30742415</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mabanglo MF]]
[[Category: Mabanglo MF]]
[[Category: Mukherjee K]]
[[Category: Mukherjee K]]
[[Category: Raushel FM]]
[[Category: Raushel FM]]

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Crystal structure of 3-keto-D-glucoside 4-epimerase, YcjR, from E. coli, apo form

PDB ID 6wn6

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