5ix7
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<StructureSection load='5ix7' size='340' side='right'caption='[[5ix7]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='5ix7' size='340' side='right'caption='[[5ix7]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[5ix7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IX7 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ix7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IX7 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.398Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AG:SILVER+ION'>AG</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ix7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ix7 OCA], [https://pdbe.org/5ix7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ix7 RCSB], [https://www.ebi.ac.uk/pdbsum/5ix7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ix7 ProSAT]</span></td></tr> |
</table> | </table> | ||
- | <div style="background-color:#fffaf0;"> | ||
- | == Publication Abstract from PubMed == | ||
- | The double-helix structure of DNA, in which complementary strands reversibly hybridize to each other, not only explains how genetic information is stored and replicated, but also has proved very attractive for the development of nanomaterials. The discovery of metal-mediated base pairs has prompted the generation of short metal-DNA hybrid duplexes by a bottom-up approach. Here we describe a metallo-DNA nanowire-whose structure was solved by high-resolution X-ray crystallography-that consists of dodecamer duplexes held together by four different metal-mediated base pairs (the previously observed C-Ag-C, as well as G-Ag-G, G-Ag-C and T-Ag-T) and linked to each other through G overhangs involved in interduplex G-Ag-G. The resulting hybrid nanowires are 2 nm wide with a length of the order of micrometres to millimetres, and hold the silver ions in uninterrupted one-dimensional arrays along the DNA helical axis. The hybrid nanowires are further assembled into three-dimensional lattices by interactions between adenine residues, fully bulged out of the double helix. | ||
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- | A metallo-DNA nanowire with uninterrupted one-dimensional silver array.,Kondo J, Tada Y, Dairaku T, Hattori Y, Saneyoshi H, Ono A, Tanaka Y Nat Chem. 2017 Oct;9(10):956-960. doi: 10.1038/nchem.2808. Epub 2017 Jul 3. PMID:28937663<ref>PMID:28937663</ref> | ||
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- | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
- | </div> | ||
- | <div class="pdbe-citations 5ix7" style="background-color:#fffaf0;"></div> | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Dairaku | + | [[Category: Synthetic construct]] |
- | [[Category: Hattori | + | [[Category: Dairaku T]] |
- | [[Category: Kondo | + | [[Category: Hattori Y]] |
- | [[Category: Ono | + | [[Category: Kondo J]] |
- | [[Category: Saneyoshi | + | [[Category: Ono A]] |
- | [[Category: Tada | + | [[Category: Saneyoshi H]] |
- | [[Category: Tanaka | + | [[Category: Tada Y]] |
- | + | [[Category: Tanaka Y]] | |
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Current revision
Crystal structure of metallo-DNA nanowire with infinite one-dimensional silver array
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Categories: Large Structures | Synthetic construct | Dairaku T | Hattori Y | Kondo J | Ono A | Saneyoshi H | Tada Y | Tanaka Y