6xe3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6xe3 is ON HOLD Authors: Hilario, E., Dunn, M.F., Mueller, L.J., Fan, L. Description: Salmonella typhimurium Tryptophan Synthase beta-S377A mutant ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Salmonella typhimurium Tryptophan Synthase beta-S377A mutant in complex with inhibitor F9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion III E(C3) at the enzyme beta-site.== | |
| - | + | <StructureSection load='6xe3' size='340' side='right'caption='[[6xe3]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6xe3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XE3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1D0:(2E)-2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-3-[(2-HYDROXYPHENYL)AMINO]PROPANOIC+ACID'>1D0</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F9F:2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL+DIHYDROGEN+PHOSPHATE'>F9F</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xe3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xe3 OCA], [https://pdbe.org/6xe3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xe3 RCSB], [https://www.ebi.ac.uk/pdbsum/6xe3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xe3 ProSAT]</span></td></tr> |
| - | [[Category: Dunn | + | </table> |
| - | [[Category: Fan | + | == Function == |
| - | [[Category: Hilario | + | [https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | ||
| + | [[Category: Dunn MF]] | ||
| + | [[Category: Fan L]] | ||
| + | [[Category: Hilario E]] | ||
| + | [[Category: Mueller LJ]] | ||
Current revision
Salmonella typhimurium Tryptophan Synthase beta-S377A mutant in complex with inhibitor F9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion III E(C3) at the enzyme beta-site.
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