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5juw
From Proteopedia
(Difference between revisions)
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<StructureSection load='5juw' size='340' side='right'caption='[[5juw]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='5juw' size='340' side='right'caption='[[5juw]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5juw]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5juw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JUW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6NR:(2~{S})-2-AZANYL-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-AZANYL-5-CYANO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYLSULFANYL]BUTANOIC+ACID'>6NR</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6NR:(2~{S})-2-AZANYL-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-AZANYL-5-CYANO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYLSULFANYL]BUTANOIC+ACID'>6NR</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5juw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5juw OCA], [https://pdbe.org/5juw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5juw RCSB], [https://www.ebi.ac.uk/pdbsum/5juw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5juw ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bayle | + | [[Category: Bayle ED]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Brown | + | [[Category: Brown PJ]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Fish | + | [[Category: Fish PV]] |
| - | [[Category: Li | + | [[Category: Li Y]] |
| - | + | [[Category: Schapira M]] | |
| - | [[Category: Schapira | + | [[Category: Spurr SS]] |
| - | [[Category: Spurr | + | [[Category: Tempel W]] |
| - | [[Category: Tempel | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Yu W]] |
| - | [[Category: Yu | + | |
| - | + | ||
| - | + | ||
Current revision
complex of Dot1l with SS148
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bayle ED | Bountra C | Brown PJ | Edwards AM | Fish PV | Li Y | Schapira M | Spurr SS | Tempel W | Weigelt J | Yu W
