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5jyj
From Proteopedia
(Difference between revisions)
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<StructureSection load='5jyj' size='340' side='right'caption='[[5jyj]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='5jyj' size='340' side='right'caption='[[5jyj]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5jyj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5jyj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JYJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyj OCA], [https://pdbe.org/5jyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jyj RCSB], [https://www.ebi.ac.uk/pdbsum/5jyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/JUNO_MOUSE JUNO_MOUSE] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.<ref>PMID:24739963</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Ishitani | + | [[Category: Ishitani R]] |
| - | [[Category: Kato | + | [[Category: Kato K]] |
| - | [[Category: Morita | + | [[Category: Morita J]] |
| - | [[Category: Nishimasu | + | [[Category: Nishimasu H]] |
| - | [[Category: Nureki | + | [[Category: Nureki O]] |
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Current revision
Crystal structure of mouse JUNO
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