Cyclic GMP-AMP synthase 3D synthase

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*cyclic GMP-AMP synthase
*cyclic GMP-AMP synthase
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**[[4km5]], [[4mkp]], [[4lev]], [[4lew]], [[4o68]], [[4o69]] – hCGAS C terminal – human<br />
+
**[[4km5]], [[4mkp]], [[4lev]], [[4lew]], [[4o68]], [[4o69]] – hCGAS Catalytic domain 157-522 – human<br />
-
**[[4jlx]] – pCGAS C terminal – pig<br />
+
**[[4jlx]] – pCGAS Catalytic domain – pig<br />
-
**[[4k8v]] – mCGAS C terminal – mouse<br />
+
**[[4k8v]], [[7kxs]] – mCGAS Catalytic domain – mouse<br />
 +
**[[7lz3]] – CGAS catalytic domain – synthetic<br />
**[[4txy]], [[4xj1]] – VcCGAS – ''Vibrio cholerae''<br />
**[[4txy]], [[4xj1]] – VcCGAS – ''Vibrio cholerae''<br />
**[[4u0l]], [[4u0n]], [[5go3]] – VcCGAS (mutant)<br />
**[[4u0l]], [[4u0n]], [[5go3]] – VcCGAS (mutant)<br />
 +
**[[7d48]] – CGAS – ''Enterobacter cloacae''<br />
*Cyclic GMP-AMP synthase complex
*Cyclic GMP-AMP synthase complex
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**[[4o67]] - hCGAS C terminal + cyclic GMP-AMP <br />
+
**[[4o67]] - hCGAS Catalytic domain + cyclic GMP-AMP <br />
-
**[[5vdo]], [[5vdt]], [[5vdp]] - hCGAS C terminal + CGAMP <br />
+
**[[5vdo]], [[5vdt]], [[5vdp]], [[6mjx]] - hCGAS Catalytic domain + CGAMP <br />
-
**[[5vdq]] - hCGAS C terminal + GPAP <br />
+
**[[6nao]] - hCGAS Catalytic domain + CGAS <br />
-
**[[5vdr]] - hCGAS C terminal + CDIMP <br />
+
**[[5vdq]] - hCGAS Catalytic domain + GPAP <br />
-
**[[5vds]] - hCGAS C terminal + CDUMP <br />
+
**[[5vdr]] - hCGAS Catalytic domain + CDIMP <br />
-
**[[6ct9]] - hCGAS C terminal (mutant) + DNA <br />
+
**[[5vds]] - hCGAS Catalytic domain + CDUMP <br />
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**[[6cta]] - hCGAS C terminal (mutant) + DNA + ATP<br />
+
**[[6edc]] - hCGAS catalytic domain + DNA <br />
-
**[[6nfg]], [[6nao]], [[5v8o]], [[5vdu]], [[5vdv]], [[5vdw]], [[6nfo]] - hCGAS C terminal + inhibitor <br />
+
**[[6ct9]] - hCGAS catalytic domain (mutant) + DNA <br />
-
**[[4kb6]] – pCGAS C terminal + DNA + ATP + GTP <br />
+
**[[6cta]] - hCGAS Catalytic domain (mutant) + DNA + ATP<br />
-
**[[4jlz]] – pCGAS C terminal + UTP<br />
+
**[[6nao]], [[5v8o]], [[5vdu]], [[5vdv]], [[5vdw]], [[6nfo]], [[6lrc]], [[6lre]], [[6lri]], [[6lrj]], [[6lrk]], [[6lrl]], [[6mju]], [[6mjw]], [[6nfg]], [[6nfo]] - hCGAS Catalytic domain + inhibitor <br />
-
**[[4k96]], [[4ley]], [[4lez]], [[4o6a]], [[5n6i]], [[5xzb]], [[5xze]], [[5xzg]] – mCGAS C terminal + DNA<br />
+
**[[6o47]] - hCGAS Catalytic domain (mutant) + inhibitor <br />
-
**[[4k97]] – mCGAS C terminal + DNA + ATP<br />
+
**[[7c0m]] – hCGAS in nucleosome – Cryo EM <br />
-
**[[4k98]], [[4k99]], [[4k9a]], [[4k9b]] – mCGAS C terminal + DNA + polynucleotide<br />
+
**[[4kb6]] – pCGAS Catalytic domain + DNA + ATP + GTP <br />
 +
**[[4jlz]] – pCGAS Catalytic domain + UTP<br />
 +
**[[4k96]], [[4ley]], [[4lez]], [[4o6a]], [[5n6i]], [[5xzb]], [[5xze]], [[5xzg]] – mCGAS Catalytic domain + DNA<br />
 +
**[[4k97]] – mCGAS Catalytic domain + DNA + ATP<br />
 +
**[[4k98]], [[4k99]], [[4k9a]], [[4k9b]] – mCGAS Catalytic domain + DNA + polynucleotide<br />
 +
**[[7bum]], [[7buq]] – mCGAS Catalytic domain + AMP + GMP <br />
 +
**[[7buj]] – mCGAS Catalytic domain + GTP + GMP <br />
 +
**[[7a08]], [[7ccq]], [[7ccr]], [[7jo9]], [[7joa]] – mCGAS in human nucleosome – Cryo EM <br />
 +
**[[6y5d]], [[6y5e]] – mCGAS (mutant) in human nucleosome – Cryo EM <br />
 +
**[[6x59]], [[6x5a]], [[6xjd]] – mCGAS catalytic domain in human nucleosome – Cryo EM <br />
**[[4txz]], [[4xj3]], [[4xj5]] – VcCGAS + GTP<br />
**[[4txz]], [[4xj3]], [[4xj5]] – VcCGAS + GTP<br />
**[[4xj4]] – VcCGAS + ATP<br />
**[[4xj4]] – VcCGAS + ATP<br />
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**[[4u03]] – VcCGAS + GTP + 5MTHFGlu2<br />
**[[4u03]] – VcCGAS + GTP + 5MTHFGlu2<br />
**[[4u0m]] – VcCGAS (mutant) + GTP + ATP + 5MTHFGlu2<br />
**[[4u0m]] – VcCGAS (mutant) + GTP + ATP + 5MTHFGlu2<br />
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}}
 
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of cyclic GMP-AMP synthase

Updated on 04-December-2022

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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