6rse
From Proteopedia
(Difference between revisions)
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==Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class== | ==Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class== | ||
| - | <StructureSection load='6rse' size='340' side='right'caption='[[6rse]]' scene=''> | + | <StructureSection load='6rse' size='340' side='right'caption='[[6rse]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSE OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RSE FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KHH:methyl+~{N}-[4-aminocarbonyl-1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[(4-ethenyl-2-fluoranyl-5-oxidanyl-phenyl)methyl]-3-fluoranyl-piperidin-4-yl]pyrazol-3-yl]carbamate'>KHH</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rse OCA], [https://pdbe.org/6rse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rse RCSB], [https://www.ebi.ac.uk/pdbsum/6rse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rse ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Janus kinase 3D structures|Janus kinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Structure based optimization of JAK1-ATP binding pocket Inhibitors in the aminopyrazole class
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