7c4i

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==High resolution structure of BRPF1 bromodomain==
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==High resolution structure of BRPF1 Bromo Domain from Biortus==
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<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]]' scene=''>
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<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7c4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [http://pdbe.org/7c4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [http://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [https://pdbe.org/7c4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [https://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
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==See Also==
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*[[Peregrin|Peregrin]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lin D]]
[[Category: Lin D]]

Current revision

High resolution structure of BRPF1 Bromo Domain from Biortus

PDB ID 7c4i

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