This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2x09

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:21, 20 December 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='2x09' size='340' side='right'caption='[[2x09]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2x09' size='340' side='right'caption='[[2x09]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2x09]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_orientalis"_pittenger_and_brigham_1956 "streptomyces orientalis" pittenger and brigham 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X09 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X09 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2x09]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X09 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=X09:AMINO-AUSTRALINE'>X09</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2x05|2x05]], [[2vzr|2vzr]], [[2vzu|2vzu]], [[2vzs|2vzs]], [[2vzt|2vzt]], [[2vzo|2vzo]], [[2vzq|2vzq]], [[2vzp|2vzp]], [[2vzv|2vzv]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=X09:AMINO-AUSTRALINE'>X09</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-1,4-beta-D-glucosaminidase Exo-1,4-beta-D-glucosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.165 3.2.1.165] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x09 OCA], [https://pdbe.org/2x09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x09 RCSB], [https://www.ebi.ac.uk/pdbsum/2x09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x09 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x09 OCA], [http://pdbe.org/2x09 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x09 RCSB], [http://www.ebi.ac.uk/pdbsum/2x09 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x09 ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/EBDG_AMYOR EBDG_AMYOR] Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has maximum activity on chitotetraose, chitopentaose and their corresponding alcohols, with a slight decrease in the rate of hydrolysis on longer chains. Has no activity against beta-D-glucopyranoside, beta-D-xylopyranoside, beta-D-mannoside, beta-D-glucuronide, beta-D-galactoside, beta-D-N-acetylgalactosamide, beta-D-N-acetylglucosaminide and alpha-D-N-acetylglucosaminide.<ref>PMID:16316314</ref> <ref>PMID:2351651</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 32: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Streptomyces orientalis pittenger and brigham 1956]]
+
[[Category: Amycolatopsis orientalis]]
-
[[Category: Exo-1,4-beta-D-glucosaminidase]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Boraston, A B]]
+
[[Category: Boraston AB]]
-
[[Category: Brzezinski, R]]
+
[[Category: Brzezinski R]]
-
[[Category: Ghinet, M G]]
+
[[Category: Ghinet MG]]
-
[[Category: Pluvinage, B]]
+
[[Category: Pluvinage B]]
-
[[Category: Stubbs, K A]]
+
[[Category: Stubbs KA]]
-
[[Category: Csxa]]
+
-
[[Category: Exo-beta-d-glucosaminidase]]
+
-
[[Category: Gh2]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Glycoside hydrolase]]
+
-
[[Category: Hydrolase]]
+

Current revision

Inhibition of the exo-beta-D-glucosaminidase CsxA by a glucosamine- configured castanospermine and an amino-australine analogue

PDB ID 2x09

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2x09"
Personal tools