6xuf

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'''Unreleased structure'''
 
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The entry 6xuf is ON HOLD until Paper Publication
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==HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21==
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<StructureSection load='6xuf' size='340' side='right'caption='[[6xuf]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
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Authors: Marsh, M.E., Scott, D.E., Hyvonen, M.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6xuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUF FirstGlance]. <br>
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Description: HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.241&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O1E:5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine'>O1E</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Scott, D.E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xuf OCA], [https://pdbe.org/6xuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xuf RCSB], [https://www.ebi.ac.uk/pdbsum/6xuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xuf ProSAT]</span></td></tr>
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[[Category: Hyvonen, M.E]]
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</table>
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[[Category: Marsh, M.E]]
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== Function ==
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[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pyrococcus furiosus DSM 3638]]
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[[Category: Hyvonen ME]]
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[[Category: Marsh ME]]
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[[Category: Scott DE]]

Current revision

HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21

PDB ID 6xuf

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