6xi9
From Proteopedia
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==X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine== | ==X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine== | ||
| - | <StructureSection load='6xi9' size='340' side='right'caption='[[6xi9]]' scene=''> | + | <StructureSection load='6xi9' size='340' side='right'caption='[[6xi9]], [[Resolution|resolution]] 2.14Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XI9 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6xi9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pedobacter_heparinus_DSM_2366 Pedobacter heparinus DSM 2366]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XI9 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=V47:9-[7-(3-carboxyphenyl)-5,6-dideoxy-beta-D-ribo-heptodialdo-1,4-furanosyl]-9H-purin-6-amine'>V47</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xi9 OCA], [https://pdbe.org/6xi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xi9 RCSB], [https://www.ebi.ac.uk/pdbsum/6xi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xi9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C6XW09_PEDHD C6XW09_PEDHD] Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.[HAMAP-Rule:MF_00993] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Pedobacter heparinus DSM 2366]] | ||
[[Category: Almo SC]] | [[Category: Almo SC]] | ||
[[Category: Bonanno JB]] | [[Category: Bonanno JB]] | ||
[[Category: Grove TL]] | [[Category: Grove TL]] | ||
Current revision
X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine
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