2yf0

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<StructureSection load='2yf0' size='340' side='right'caption='[[2yf0]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='2yf0' size='340' side='right'caption='[[2yf0]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YF0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yf0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YF0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf0 OCA], [http://pdbe.org/2yf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yf0 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf0 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf0 OCA], [https://pdbe.org/2yf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTMR6_HUMAN MTMR6_HUMAN]] Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.<ref>PMID:15831468</ref> <ref>PMID:16847315</ref>
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[https://www.uniprot.org/uniprot/MTMR6_HUMAN MTMR6_HUMAN] Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.<ref>PMID:15831468</ref> <ref>PMID:16847315</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Berglund, H]]
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[[Category: Berglund H]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Collins, R]]
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[[Category: Collins R]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Flodin, S]]
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[[Category: Flodin S]]
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[[Category: Flores, A]]
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[[Category: Flores A]]
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[[Category: Graslund, S]]
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[[Category: Graslund S]]
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[[Category: Hammarstrom, M]]
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[[Category: Hammarstrom M]]
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[[Category: Johansson, I]]
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[[Category: Johansson I]]
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[[Category: Karlberg, T]]
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[[Category: Karlberg T]]
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[[Category: Kotenyova, T]]
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[[Category: Kotenyova T]]
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[[Category: Kouznetsova, E]]
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[[Category: Kouznetsova E]]
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[[Category: Moche, M]]
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[[Category: Moche M]]
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[[Category: Nordlund, P]]
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[[Category: Nordlund P]]
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[[Category: Nyman, T]]
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[[Category: Nyman T]]
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[[Category: Persson, C]]
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[[Category: Persson C]]
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[[Category: Schuler, H]]
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[[Category: Schuler H]]
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[[Category: Schutz, P]]
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[[Category: Schutz P]]
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[[Category: Siponen, M I]]
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[[Category: Siponen MI]]
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[[Category: Thorsell, A G]]
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[[Category: Thorsell AG]]
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[[Category: Tresaugues, L]]
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[[Category: Tresaugues L]]
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[[Category: VanDenBerg, S]]
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[[Category: VanDenBerg S]]
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[[Category: Wahlberg, E]]
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[[Category: Wahlberg E]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Welin, M]]
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[[Category: Welin M]]
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[[Category: Hydrolase]]
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Current revision

Human Myotubularin related protein 6 (MTMR6)

PDB ID 2yf0

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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