2yr1

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Current revision (09:04, 25 October 2023) (edit) (undo)
 
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<StructureSection load='2yr1' size='340' side='right'caption='[[2yr1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2yr1' size='340' side='right'caption='[[2yr1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geoka Geoka]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YR1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YR1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yr1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus_HTA426 Geobacillus kaustophilus HTA426]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YR1 FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yr1 OCA], [http://pdbe.org/2yr1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yr1 RCSB], [http://www.ebi.ac.uk/pdbsum/2yr1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yr1 ProSAT], [http://www.topsan.org/Proteins/RSGI/2yr1 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yr1 OCA], [https://pdbe.org/2yr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yr1 RCSB], [https://www.ebi.ac.uk/pdbsum/2yr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yr1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yr1 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AROD_GEOKA AROD_GEOKA]] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.[HAMAP-Rule:MF_00214]
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[https://www.uniprot.org/uniprot/AROD_GEOKA AROD_GEOKA] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.[HAMAP-Rule:MF_00214]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate dehydratase]]
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[[Category: Geobacillus kaustophilus HTA426]]
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[[Category: Geoka]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bessho, Y]]
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[[Category: Bessho Y]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Chrzas, J]]
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[[Category: Chrzas J]]
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[[Category: Fu, Z Q]]
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[[Category: Fu ZQ]]
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[[Category: Kagawa, W]]
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[[Category: Kagawa W]]
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[[Category: Kurumizaka, H]]
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[[Category: Kurumizaka H]]
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[[Category: Structural genomic]]
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[[Category: Wang BC]]
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[[Category: Wang, B C]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: 3-dehydroquinase]]
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[[Category: Amino acid biosynthesis]]
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[[Category: Lyase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure of 3-dehydroquinate dehydratase from Geobacillus kaustophilus HTA426

PDB ID 2yr1

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