This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2yxs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:10, 25 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
==Crystal Sturcture of N-terminal domain of human galectin-8 with D-lactose==
+
==Crystal Structure of N-terminal domain of human galectin-8 with D-lactose==
<StructureSection load='2yxs' size='340' side='right'caption='[[2yxs]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
<StructureSection load='2yxs' size='340' side='right'caption='[[2yxs]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2yxs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YXS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2yxs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LAT:BETA-LACTOSE'>LAT</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yv8|2yv8]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxs OCA], [https://pdbe.org/2yxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxs RCSB], [https://www.ebi.ac.uk/pdbsum/2yxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxs ProSAT], [https://www.topsan.org/Proteins/RSGI/2yxs TOPSAN]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxs OCA], [http://pdbe.org/2yxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxs RCSB], [http://www.ebi.ac.uk/pdbsum/2yxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxs ProSAT], [http://www.topsan.org/Proteins/RSGI/2yxs TOPSAN]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 22: Line 23:
==See Also==
==See Also==
*[[Galectin 3D structures|Galectin 3D structures]]
*[[Galectin 3D structures|Galectin 3D structures]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Kishishita, S]]
+
[[Category: Kishishita S]]
-
[[Category: Murayama, K]]
+
[[Category: Murayama K]]
-
[[Category: Nishino, A]]
+
[[Category: Nishino A]]
-
[[Category: Structural genomic]]
+
[[Category: Shirouzu M]]
-
[[Category: Shirouzu, M]]
+
[[Category: Terada T]]
-
[[Category: Terada, T]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S]]
+
-
[[Category: Galectin]]
+
-
[[Category: Lactose]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Sugar binding protein]]
+
-
[[Category: Suger-binding]]
+

Current revision

Crystal Structure of N-terminal domain of human galectin-8 with D-lactose

PDB ID 2yxs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools