6zqd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1== | |
| + | <StructureSection load='6zqd' size='340' side='right'caption='[[6zqd]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6zqd]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZQD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zqd OCA], [https://pdbe.org/6zqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zqd RCSB], [https://www.ebi.ac.uk/pdbsum/6zqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zqd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UTP8_YEAST UTP8_YEAST] Involved in nucleolar processing of pre-18S ribosomal RNA. Also has a role in nuclear tRNA export. It acts between the steps of tRNA maturation/aminoacylation and its subsequent translocation out of the nucleus. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).<ref>PMID:12068309</ref> <ref>PMID:12794079</ref> <ref>PMID:15489292</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Adenosine dimethyltransferase 3D structures|Adenosine dimethyltransferase 3D structures]] | |
| - | + | *[[Ribosome 3D structures|Ribosome 3D structures]] | |
| - | [[Category: | + | *[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Beckmann R]] | ||
| + | [[Category: Berninghausen O]] | ||
| + | [[Category: Cheng J]] | ||
| + | [[Category: Hurt E]] | ||
| + | [[Category: Lau B]] | ||
| + | [[Category: Venuta GL]] | ||
Current revision
Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1
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