Glucocorticoid receptor 3D structures
From Proteopedia
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| + | *Glucocorticoid receptor | ||
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| + | **[[7kw7]] - hGCR + Hsp90 + Hsp70 + HOP – human – Cryo EM<br /> | ||
*Glucocorticoid receptor residues 89-158 | *Glucocorticoid receptor residues 89-158 | ||
| - | **[[5va7]], [[5va0]] - hGCR + DNA | + | **[[5va7]], [[5va0]] - hGCR + DNA <br /> |
*Glucocorticoid receptor DBD domain residues 391-480 | *Glucocorticoid receptor DBD domain residues 391-480 | ||
**[[6cfn]] - hGCR DBD <br /> | **[[6cfn]] - hGCR DBD <br /> | ||
| - | **[[4hn5]], [[4hn6]], [[5emp]], [[5emq]], [[5emc]], [[5e69]], [[5e6a]], [[5e6b]], [[5e6c]], [[5e6d]], [[5cbx]], [[5cby]], [[5cbz]], [[6bqu]] - hGCR DBD + DNA<br /> | + | **[[4hn5]], [[4hn6]], [[5emp]], [[5emq]], [[5emc]], [[5e69]], [[5e6a]], [[5e6b]], [[5e6c]], [[5e6d]], [[5cbx]], [[5cby]], [[5cbz]], [[6bqu]], [[6x6d]], [[6x6e]] - hGCR DBD + DNA<br /> |
**[[5cc1]] - hGCR DBD (mutant) + DNA <br /> | **[[5cc1]] - hGCR DBD (mutant) + DNA <br /> | ||
**[[1gdc]], [[2gda]], [[1rgd]] – rGCR DBD – NMR – rat<br /> | **[[1gdc]], [[2gda]], [[1rgd]] – rGCR DBD – NMR – rat<br /> | ||
**[[3g9p]], [[3fyl]], [[3g6p]], [[3g6q]], [[3g6r]], [[3g6t]], [[3g6u]], [[3g8u]], [[3g8x]], [[3g97]], [[3g99]], [[3g9i]], [[3g9m]], [[3g9j]], [[3g9o]], [[1glu]], [[1lat]], [[1r4o]], [[1r4r]] - rGCR DBD + DNA<br /> | **[[3g9p]], [[3fyl]], [[3g6p]], [[3g6q]], [[3g6r]], [[3g6t]], [[3g6u]], [[3g8u]], [[3g8x]], [[3g97]], [[3g99]], [[3g9i]], [[3g9m]], [[3g9j]], [[3g9o]], [[1glu]], [[1lat]], [[1r4o]], [[1r4r]] - rGCR DBD + DNA<br /> | ||
| - | **[[6bsf]] - GCR DBD + DNA – cotton-top tamarin<br /> | + | **[[6bse]], [[6bsf]] - GCR DBD + DNA – cotton-top tamarin<br /> |
*Glucocorticoid receptor LBD domain residues 500-777 complex with NCOA peptide | *Glucocorticoid receptor LBD domain residues 500-777 complex with NCOA peptide | ||
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**[[3k23]] - hGCR LBD (mutant) + NCOA2 peptide + prolinamide<br /> | **[[3k23]] - hGCR LBD (mutant) + NCOA2 peptide + prolinamide<br /> | ||
**[[6el9]], [[6el6]], [[6el7]], [[5nft]] - hGCR LBD + NCOA2 peptide + modulator<br /> | **[[6el9]], [[6el6]], [[6el7]], [[5nft]] - hGCR LBD + NCOA2 peptide + modulator<br /> | ||
| - | **[[5nfp]] - hGCR LBD + NCOA2 peptide + drug<br /> | + | **[[5nfp]], [[6w9m]] - hGCR LBD + NCOA2 peptide + drug<br /> |
**[[3gn8]] - hGCR LBD + NCOA2 peptide + steroid<br /> | **[[3gn8]] - hGCR LBD + NCOA2 peptide + steroid<br /> | ||
**[[4e2j]] - anGCR LBD + NCOA2 peptide + steroid - ancestral<br /> | **[[4e2j]] - anGCR LBD + NCOA2 peptide + steroid - ancestral<br /> | ||
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**[[5uc3]] - hGCR LBD (mutant) + RU-486<br /> | **[[5uc3]] - hGCR LBD (mutant) + RU-486<br /> | ||
**[[3k22]] - hGCR LBD (mutant) + transcriptional intermediary factor 2 peptide + alaninamide<br /> | **[[3k22]] - hGCR LBD (mutant) + transcriptional intermediary factor 2 peptide + alaninamide<br /> | ||
| + | **[[7krj]] - hGCR LBD (mutant) + Hsp90 + P23 – Cryo EM<br /> | ||
| + | **[[8ffw]] - hGCR LBD (mutant) + Hsp90 + Fkbp51 – Cryo EM<br /> | ||
| + | **[[8ffv]] - hGCR LBD (mutant) + Hsp90 + Fkbp52 – Cryo EM<br /> | ||
**[[6dxk]] – hGCR LBD + antagonist<br /> | **[[6dxk]] – hGCR LBD + antagonist<br /> | ||
| + | **[[7prx]] – hGCR LBD + PGC1A coactivator + modulator<br /> | ||
| + | **[[7prw]] – hGCR LBD + PGC1A coactivator + modulator + DNA<br /> | ||
| + | **[[7prv]] – hGCR LBD + PGC1A coactivator + DNA + drug<br /> | ||
*Glucocorticoid receptor 2 | *Glucocorticoid receptor 2 | ||
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**[[4e2j]] – anGCR2 LBD ancestral + NCOA2 peptide + steroid<br /> | **[[4e2j]] – anGCR2 LBD ancestral + NCOA2 peptide + steroid<br /> | ||
**[[6nwl]] – anGCR2 LBD ancestral + cortisol + PPARGC peptide<br /> | **[[6nwl]] – anGCR2 LBD ancestral + cortisol + PPARGC peptide<br /> | ||
| - | **[[6nwk]] – anGCR2 LBD ancestral + | + | **[[6nwk]], [[6w9k]], [[6w9l]] – anGCR2 LBD ancestral + drug + PPARGC peptide<br /> |
**[[5uc1]] – GCR2 LBD + RU-486 – ''Heterocephalus glaber''<br /> | **[[5uc1]] – GCR2 LBD + RU-486 – ''Heterocephalus glaber''<br /> | ||
Current revision
3D structures of glucocorticoid receptor
Updated on 10-July-2025
