Glutamyl-tRNA(Gln) amidotransferase

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==3D structures of glutamyl-tRNA(Gln) amidotransferase==
==3D structures of glutamyl-tRNA(Gln) amidotransferase==
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[[Glutamyl-tRNA(Gln) amidotransferase 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Glu-ADT subunits A,B,C
 
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**[[3ip4]], [[2g5h]], [[2df4]] - SaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Asp/Glu-ADT subunit C - ''Staphylococcus aureus''<br />
 
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**[[2f2a]] - SaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Asp/Glu-ADT subunit C + Gln<br />
 
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**[[2dqn]] - SaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Asp/Glu-ADT subunit C + Asn<br />
 
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**[[2g5i]] - SaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Asp/Glu-ADT subunit C + ADP<br />
 
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**[[3h0m]] - AaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Glu-ADT subunit C + Gln - ''Aquifex aeolicus''<br />
 
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**[[3h0l]] - AaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Glu-ADT subunit C + Asn + ADP<br />
 
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**[[3h0r]] - AaGlu-ADT subunit A + Asp/Glu-ADT subunit B + Glu-ADT subunit C + Asn + Asp + ADP + ATP<br />
 
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**[[4wj3]] - Glu-ADT subunit A + Asp/Glu-ADT subunit B + Glu-ADT subunit C + AspRS + tRNA - ''Pseudomonas aeruginosa''<br />
 
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**[[3kfu]] - Glu-ADT subunit A + Asp/Glu-ADT subunit B + Glu-ADT subunit C + AspRS + tRNA - ''Thermus thermophilus''<br />
 
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**[[2gi3]] - TmGlu-ADT subunit A - ''Thermotoga maritima''<br />
 
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**[[3al0]] - TmGlu-ADT subunit A + Asp/Glu-ADT subunit B + GluRS + tRNA<br />
 
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**[[5c5z]] - Glu-ADT subunit A – ''Escherichia coli''<br />
 
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**[[5ewq]] - Glu-ADT subunit A – ''Bacillus anthracis''<br />
 
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*Glu-ADT subunits A,B,F
 
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**[[4n0h]] - yGlu-ADT subunit A + Glu-ADT subunit B + Glu-ADT subunit F - yeast<br />
 
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**[[4n0i]] - yGlu-ADT subunit A + Glu-ADT subunit B + Glu-ADT subunit F + Gln<br />
 
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*Glu-ADT subunits D,E
 
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**[[1zq1]] - Glu-ADT subunit D + Glu-ADT subunit E + Asp - ''Pyrococcus abyssi''<br />
 
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**[[2d6f]] - Glu-ADT subunit D + Glu-ADT subunit E + tRNA - ''Methanothermobacter thermautotrophicus''<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Yeast Glu-ADT subunit A (cyan) + subunit B (green) + subunit F (pink) complex with Gln and NO3- ion (PDB code 4n0i)

Drag the structure with the mouse to rotate

3D structures of glutamyl-tRNA(Gln) amidotransferase

Glutamyl-tRNA(Gln) amidotransferase 3D structures

References

  1. Curnow AW, Tumbula DL, Pelaschier JT, Min B, Soll D. Glutamyl-tRNA(Gln) amidotransferase in Deinococcus radiodurans may be confined to asparagine biosynthesis. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):12838-43. doi:, 10.1073/pnas.95.22.12838. PMID:9789001 doi:http://dx.doi.org/10.1073/pnas.95.22.12838
  2. Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, Gonzalez C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernandez-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK. Pathogenic variants in glutamyl-tRNA(Gln) amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun. 2018 Oct 3;9(1):4065. doi: 10.1038/s41467-018-06250-w. PMID:30283131 doi:http://dx.doi.org/10.1038/s41467-018-06250-w
  3. Araiso Y, Huot JL, Sekiguchi T, Frechin M, Fischer F, Enkler L, Senger B, Ishitani R, Becker HD, Nureki O. Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases. Nucleic Acids Res. 2014 Apr 1. PMID:24692665 doi:http://dx.doi.org/10.1093/nar/gku234

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