7jkx

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(New page: '''Unreleased structure''' The entry 7jkx is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures)
Current revision (15:05, 18 October 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7jkx is ON HOLD until Paper Publication
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==Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6==
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<StructureSection load='7jkx' size='340' side='right'caption='[[7jkx]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7jkx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JKX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JKX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=Y36:N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-[1-methyl-5-(methylamino)-6-oxo-1,6-dihydropyridin-3-yl]-1H-indol-4-yl}ethanesulfonamide'>Y36</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jkx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jkx OCA], [https://pdbe.org/7jkx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jkx RCSB], [https://www.ebi.ac.uk/pdbsum/7jkx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jkx ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
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Authors:
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==See Also==
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
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Description:
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Dubrovyskyii O]]
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[[Category: Huang F]]
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[[Category: Li Y]]
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[[Category: Ratia KM]]
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[[Category: Shen Z]]
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[[Category: Thatcher GR]]
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[[Category: Xiong R]]
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[[Category: Zhao J]]

Current revision

Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6

PDB ID 7jkx

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OCA

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