Proteopedia:Featured SEL/6

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<tr><td><div class='scrolling '>'''Coronavirus Spike Protein Transformation'''<br>
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<tr><td><div class='scrolling '>'''Coronavirus Spike Protein Membrane Fusion'''<br>
''by Eric Martz''<br>
''by Eric Martz''<br>
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SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. Similar conformational transformations have been observed for the spike protein of SARS-CoV and mouse hepatitis virus, among others. These rearrangements also have much in common with the membrane fusion mechansism of influenza hemagglutinin.
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SARS-CoV-2 spike protein "spears" the host membrane with a <font color="#0060ff">'''fusion peptide'''</font> and drags the virus envelope membrane <font color="red">'''transmembrane domain'''</font> close to the host membrane, initiating fusion. This moves the virus RNA genome into the host cell, initiating infection.
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>>> [[SARS-CoV-2_spike_protein_fusion_transformation|Visit this page]] >>>
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<br>>>> [[SARS-CoV-2_spike_protein_fusion_transformation|Visit this page]] >>>
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Coronavirus Spike Protein Membrane Fusion

by Eric Martz
SARS-CoV-2 spike protein "spears" the host membrane with a fusion peptide and drags the virus envelope membrane transmembrane domain close to the host membrane, initiating fusion. This moves the virus RNA genome into the host cell, initiating infection.
>>> Visit this page >>>

Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Jaime Prilusky

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