6zzr

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(New page: '''Unreleased structure''' The entry 6zzr is ON HOLD Authors: Wang, F., Lin, D., Cheng, W., Bao, X., Zhu, B., Shang, H. Description: The Crystal Structure of human LDHA from Wuxi Biort...)
Current revision (12:01, 1 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6zzr is ON HOLD
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==The Crystal Structure of human LDHA from Biortus==
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<StructureSection load='6zzr' size='340' side='right'caption='[[6zzr]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6zzr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZZR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zzr OCA], [https://pdbe.org/6zzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zzr RCSB], [https://www.ebi.ac.uk/pdbsum/6zzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zzr ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[https://omim.org/entry/612933 612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]
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Authors: Wang, F., Lin, D., Cheng, W., Bao, X., Zhu, B., Shang, H.
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==See Also==
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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Description: The Crystal Structure of human LDHA from Wuxi Biortus.
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Bao, X]]
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__TOC__
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[[Category: Lin, D]]
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</StructureSection>
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[[Category: Wang, F]]
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[[Category: Homo sapiens]]
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[[Category: Zhu, B]]
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[[Category: Large Structures]]
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[[Category: Shang, H]]
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[[Category: Bao X]]
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[[Category: Cheng, W]]
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[[Category: Cheng W]]
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[[Category: Lin D]]
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[[Category: Shang H]]
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[[Category: Wang F]]
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[[Category: Zhu B]]

Current revision

The Crystal Structure of human LDHA from Biortus

PDB ID 6zzr

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