6yg6

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==Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor TL10-105==
==Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor TL10-105==
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<StructureSection load='6yg6' size='340' side='right'caption='[[6yg6]]' scene=''>
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<StructureSection load='6yg6' size='340' side='right'caption='[[6yg6]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YG6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YG6 FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YG6 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yg6 OCA], [http://pdbe.org/6yg6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6yg6 RCSB], [http://www.ebi.ac.uk/pdbsum/6yg6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6yg6 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OQ8:~{N}-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-[[(3~{S})-1-propanoylpyrrolidin-3-yl]amino]pyrimidin-4-yl]oxy-benzamide'>OQ8</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yg6 OCA], [https://pdbe.org/6yg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yg6 RCSB], [https://www.ebi.ac.uk/pdbsum/6yg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yg6 ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
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*[[Mitogen-activated protein kinase kinase 3D structures|Mitogen-activated protein kinase kinase 3D structures]]
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</StructureSection>
</StructureSection>

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Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor TL10-105

PDB ID 6yg6

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