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6tic

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Current revision (13:02, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6tic' size='340' side='right'caption='[[6tic]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
<StructureSection load='6tic' size='340' side='right'caption='[[6tic]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6tic]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/A._niger A. niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TIC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TIC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6tic]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TIC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ND8:benzothiophene+2+carboxylic+acid'>ND8</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.281&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6tib|6tib]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ND8:benzothiophene+2+carboxylic+acid'>ND8</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDC1, ATCC64974_75990, CAN33_0036860 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5061 A. niger])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tic OCA], [https://pdbe.org/6tic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tic RCSB], [https://www.ebi.ac.uk/pdbsum/6tic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tic ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tic OCA], [http://pdbe.org/6tic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tic RCSB], [http://www.ebi.ac.uk/pdbsum/6tic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tic ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A3F3RNU4_ASPNG A0A3F3RNU4_ASPNG]] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]
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[https://www.uniprot.org/uniprot/A0A3F3RNU4_ASPNG A0A3F3RNU4_ASPNG] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: A. niger]]
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[[Category: Aspergillus niger]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Phenacrylate decarboxylase]]
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[[Category: Leys D]]
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[[Category: Leys, D]]
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[[Category: Aromatic acid]]
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[[Category: Ligase]]
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[[Category: Prfmn]]
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[[Category: Ubid]]
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Current revision

Structure of A. niger Fdc I327S variant in complex with benzothiophene 2 carboxylic acid

PDB ID 6tic

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