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Helicase 3D structures

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Current revision (08:42, 10 May 2023) (edit) (undo)
 
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Line 21: Line 21:
**[[4n8o]], [[5n8o]] - EcHel I + DNA<br />
**[[4n8o]], [[5n8o]] - EcHel I + DNA<br />
**[[2a0i]] - EcHel I (mutant) + DNA<BR />
**[[2a0i]] - EcHel I (mutant) + DNA<BR />
 +
**[[6fws]], [[6fwr]] – EcHel I + DNA + ADP <br />
**[[1e0j]], [[1e0k]] – Hel 4D domain – Phage T7
**[[1e0j]], [[1e0k]] – Hel 4D domain – Phage T7
Line 27: Line 28:
**[[1q2z]], [[1rw2]] – hHel II KU86 C terminal – human - NMR<BR />
**[[1q2z]], [[1rw2]] – hHel II KU86 C terminal – human - NMR<BR />
**[[5y58]] – yHel II + DNA – yeast<br />
**[[5y58]] – yHel II + DNA – yeast<br />
 +
**[[6yhz]] – yHel II C terminal - NMR<br />
 +
**[[7egs]] – yHel II C terminal + RNA polymerase<br />
**[[5y59]] – yHel II subunit 2 + Sir4P peptide<br />
**[[5y59]] – yHel II subunit 2 + Sir4P peptide<br />
**[[3lfu]] – EcHel II <BR />
**[[3lfu]] – EcHel II <BR />
Line 32: Line 35:
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[2is4]], [[2is6]] - EcHel II (mutant) + ADP + DNA<BR />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
**[[4c2t]], [[4c2u]], [[4c30]] – DrHel II + DNA - ''Deinococcus radiodurans''<br />
-
**[[6ppj]] – MsHel (mutant) – ''Mycobacterium smegmatis'' – Cryo EM<br />
+
**[[6ppj]], [[7lhl]] – MsHel (mutant) – ''Mycobacterium smegmatis'' – Cryo EM<br />
**[[6ppr]], [[6ppu]] – MsHel + DNA – Cryo EM<br />
**[[6ppr]], [[6ppu]] – MsHel + DNA – Cryo EM<br />
 +
**[[6yi2]] – EcHel 645-720 - NMR<br />
 +
**[[7egt]] – TtHel II + UvrB – ''Thermus thermophilus''<br />
*ATP-dependent helicase ATRX
*ATP-dependent helicase ATRX
Line 52: Line 57:
**[[5gn1]] – yFun C-terminal<br />
**[[5gn1]] – yFun C-terminal<br />
-
*ATP-dependent helicase Rho
+
*ATP-dependent helicase Rho or transcription termination factor Rho
**[[3l0o]] – TmRho – ''Thermotoga maritima''<BR />
**[[3l0o]] – TmRho – ''Thermotoga maritima''<BR />
-
**[[3ice]] – EcRho + ADP + BeF3 + RNA<BR />
+
**[[6wa8]] – EcRho + ATP<br />
-
**[[2ht1]] - EcRho + RNA<BR />
+
**[[3ice]], [[8e5l]] – EcRho + ADP + BeF3 + RNA<BR />
-
**[[1a8v]], [[1a62]] – EcRho RNA-binding domain<br />
+
**[[2ht1]], [[5jjl]] - EcRho + RNA<BR />
 +
**[[8e6w]] - EcRho + RNA – Cryo EM<br />
 +
**[[1a8v]], [[1a62]] – EcRho RNA-binding domain 1-118<br />
**[[1a63]] - EcRho RNA-binding domain – NMR<br />
**[[1a63]] - EcRho RNA-binding domain – NMR<br />
**[[2a8v]] – EcRho RNA-binding domain + RNA<br />
**[[2a8v]] – EcRho RNA-binding domain + RNA<br />
 +
**[[5jjk]] – EcRho (mutant) + RNA<br />
**[[1pv4]] – EcRho + DNA<br />
**[[1pv4]] – EcRho + DNA<br />
**[[1pvo]] – EcRho + ssRNA + ANPPNP<br />
**[[1pvo]] – EcRho + ssRNA + ANPPNP<br />
-
**[[1xpr]], [[1xpu]], [[1xpo]] - EcRho + ssRNA + antibiotic
+
**[[1xpr]], [[1xpu]], [[1xpo]] - EcRho + ssRNA + antibiotic<br />
 +
**[[6duq]] – EcRho + NusG + Ru12<br />
 +
**[[7x2r]] – EcRho in transcription termination complex<br />
 +
**[[6xas]], [[6xav]], [[6z9p]], [[6z9s]], [[6z9t]], [[6z9q]], [[6z9r]], [[7adc]], [[7adb]], [[7add]], [[7ade]], [[8e3h]], [[8e5p]], [[8e70]] – EcRho in transcription termination complex – Cryo EM<br />
 +
**[[7oqh]] – MtRho in transcription termination complex – Cryo EM<br />
-
*ATP-dependent helicase MFD
+
*ATP-dependent helicase MFD see [[Transcription-repair coupling factor]]
-
 
+
-
**[[3hjh]] – EcMFD motor domain
+
*ATP-dependent helicase HEPA
*ATP-dependent helicase HEPA
-
**[[6bog]] – EcHEPA
+
**[[6bog]] – EcHEPA<br />
 +
**[[4s20]], [[7mkn]], [[7mkq]] – EcHEPA in RNA polymerase complex – Cryo EM<br />
 +
**[[7m8e]] – EcHEPA in elongation complex – Cryo EM<br />
*ATP-dependent helicase E1
*ATP-dependent helicase E1
-
**[[2v9p]] – PvE1 helicase domain – Bovine papillomavirus<br />
+
**[[2v9p]], [[5a9k]] – bPvE1 helicase domain – Bovine papillomavirus<br />
-
**[[2gxa]] – PvE1 + DNA + Mg-ADP<br />
+
**[[2gxa]] – bPvE1 + DNA + Mg-ADP<br />
-
**[[1tue]] – PvE1 + E2 – human papillomavirus
+
**[[7apd]] – bPvE1 in replication fork complex – Cryo EM<br />
 +
**[[1tue]] – hPvE1 + E2 – human papillomavirus
*ATP-dependent helicase CHD
*ATP-dependent helicase CHD
Line 83: Line 96:
**[[4b4c]] – hCHD1 DNA-binding domain<br />
**[[4b4c]] – hCHD1 DNA-binding domain<br />
**[[2b2t]], [[2b2u]], [[2b2v]], [[2b2w]] – hCHD1 (mutant) + histone H3 tail<br />
**[[2b2t]], [[2b2u]], [[2b2v]], [[2b2w]] – hCHD1 (mutant) + histone H3 tail<br />
-
**[[4nw2]] – hCHD1 + NS1 peptide<br />
+
**[[4nw2]], [[4o42]] – hCHD1 + NS1 peptide<br />
-
**[[2ee1]] – hCHD4 chromodomain – NMR<br />
+
**[[2n5n]] – hCHD1 N-terminal – NMR<br />
-
**[[2l5u]] – hCHD4 PHD1 domain – NMR<br />
+
**[[2ee1]] – hCHD4 chromodomain 2 618-674 – NMR<br />
-
**[[2l75]] – hCHD4 PHD2 domain + histone H3 peptide– NMR<br />
+
**[[4o9i]] – hCHD4 chromodomain 1+2 499-677 <br />
 +
**[[2l5u]] – hCHD4 PHD1 domain 365-420 – NMR<br />
 +
**[[6q3m]] – hCHD4 PHD2+chromodomain 1,2 <br />
 +
**[[2l75]] – hCHD4 PHD2 domain 446-501 + histone H3 peptide – NMR<br />
 +
**[[6ryr]], [[6ryu]] – hCHD4 in nucleosome – Cryo EM<br />
 +
**[[6guu]] – hCHD5 PHD2 domain <br />
**[[2epb]] – hCHD6 chromodomain – NMR<br />
**[[2epb]] – hCHD6 chromodomain – NMR<br />
**[[2ckc]], [[2v0e]], [[2v0f]] – hCHD7 BRK domain - NMR <br />
**[[2ckc]], [[2v0e]], [[2v0f]] – hCHD7 BRK domain - NMR <br />
Line 92: Line 110:
**[[2cka]] – hCHD8 <br />
**[[2cka]] – hCHD8 <br />
**[[2h1e]], [[2xb0]], [[3mwy]] – yCHD1 chromodomain<BR />
**[[2h1e]], [[2xb0]], [[3mwy]] – yCHD1 chromodomain<BR />
-
**[[2dy7]] - yCHD1 chromodomain 1 – NMR<BR />
+
**[[2dy7]] - yCHD1 chromodomain 1 1006-1274 – NMR<BR />
**[[2dy8]] - yCHD1 chromodomain 2 – NMR<BR />
**[[2dy8]] - yCHD1 chromodomain 2 – NMR<BR />
**[[3ted]] - yCHD1 chromodomain 1 + DNA<br />
**[[3ted]] - yCHD1 chromodomain 1 + DNA<br />
 +
**[[5j70]] - yCHD1 chromodomain 1 + DNA<br />
 +
**[[5o9g]], [[6g0l]], [[7nkx]], [[7tn2]] - yCHD1 in nucleosome – Cryo EM<br />
 +
 +
*ATP-dependent helicase Sth1
 +
 +
**[[6kmb]], [[6mr4]], [[6uy1]] – ySth1 bromodomain 1248-1359 <br />
 +
**[[6lqz]] – ySth1 1183-1240 + TFIID subunit 14 - NMR<br />
 +
**[[6kmj]], [[7f3s]] – ySth1 bromodomain + hisone H3<br />
 +
**[[6vz4]], [[6vzg]] – ySth1 + ARP7 + ARP9 + RTT102 – Cryo EM<br />
 +
**[[6k15]], [[6v8o]], [[6v92]] – ySth1 in RSC core – Cryo EM<br />
 +
**[[6kw3]], [[6kw4]], [[6kw5]], [[6tda]] – ySth1 in RSC + nucleosome – Cryo EM<br />
 +
 +
*ATP-dependent helicase GTF2F2 or general transcription factor IIF subunit 2
 +
 +
**[[7nvr]], [[7nvt]], [[7nvu]], [[7nvy]], [[7nvz]], [[7nw0]] – hGTF2F2 in RNA polymerase II core – Cryo EM<br />
 +
**[[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]], [[6o9l]], [[7edx]], [[7eg7]], [[7eg8]], [[7eg9]], [[7ega]], [[7egb]], [[7egc]] – hGTF2F2 in core-PIC – Cryo EM<br />
 +
 +
*ATP-dependent DNA helicase
 +
 +
**[[7a8r]] – bADDH + ADP - bovine<br />
 +
**[[8add]] – ADDH - zebrafish<br />
*ATP-dependent DNA helicase PIF1
*ATP-dependent DNA helicase PIF1
Line 102: Line 141:
**[[5o6b]], [[5o6d]] – yPIF residues 237-780 + DNA + ATP<br />
**[[5o6b]], [[5o6d]] – yPIF residues 237-780 + DNA + ATP<br />
**[[5o6e]] – yPIF residues 237-780 + DNA + ADP<br />
**[[5o6e]] – yPIF residues 237-780 + DNA + ADP<br />
 +
**[[6s3e]], [[7ada]] – ToPIF residues 64-507 – ''Thermus oshimai''<br />
 +
**[[6xzt]] – ToPIF (mutant)<br />
 +
**[[6s3p]], [[7bil]], [[7oar]] – ToPIF + DNA<br />
 +
**[[6s3h]], [[6s3i]], [[6s3m]], [[6s3n]], [[6s3o]] – ToPIF + DNA + ADP<br />
 +
**[[5ftd]] – BaPIF - ''Bacterioides''<br />
 +
**[[5fte]], [[6l3g]] – BaPIF + DNA + ADP<br />
 +
**[[5ftb]] – BaPIF + AMPPNP<br />
 +
**[[5ftc]], [[5ftf]] – BaPIF + ADP<br />
 +
**[[7otj]] – PIF + DNA + ADP – ''Candida albicans''<br />
*ATP-dependent DNA helicase TA0057
*ATP-dependent DNA helicase TA0057
Line 119: Line 167:
**[[5e7i]] - hDDX3X residues 133-584<br />
**[[5e7i]] - hDDX3X residues 133-584<br />
**[[2jgn]] – hDDX3X helicase domain residues 408-579<BR />
**[[2jgn]] – hDDX3X helicase domain residues 408-579<BR />
 +
**[[4a4d]] – hDDX5 N-terminal<br />
 +
**[[4ct5]] – hDDX6 95-469<br />
 +
**[[6uv0]] – hDDX17 core domain <br />
**[[3ly5]] – hDDX18 dead domain<BR />
**[[3ly5]] – hDDX18 dead domain<BR />
**[[6l5l]], [[6l5o]] – hDDX21 residues 120-495 (mutant)<br />
**[[6l5l]], [[6l5o]] – hDDX21 residues 120-495 (mutant)<br />
-
**[[6l5m]] – hDDX21 + AMP<br />
 
-
**[[6l5n]] – hDDX21 + RNA<br />
 
**[[2rb4]] – hDDX25 helicase domain<BR />
**[[2rb4]] – hDDX25 helicase domain<BR />
**[[2p6n]] – hDDX41 helicase domain (mutant) <BR />
**[[2p6n]] – hDDX41 helicase domain (mutant) <BR />
 +
**[[5gvr]], [[5gvs]] – hDDX41 DEAD domain 169-399<br />
 +
**[[8dpe]] – hDDX42<br />
**[[2e29]], [[2m3d]] - hDDX50 GUCT domain - NMR<BR />
**[[2e29]], [[2m3d]] - hDDX50 GUCT domain - NMR<BR />
 +
**[[3iuy]] – hDDX53<br />
**[[1vec]] – hP54 N terminal<BR />
**[[1vec]] – hP54 N terminal<BR />
-
**[[3fho]] – DBP5 – fission yeast<BR />
+
**[[3fho]] – fyDbp5 – fission yeast<BR />
-
**[[2kbe]] – yDBP5 N terminal – NMR<BR />
+
**[[8ark]] – yDbp2<br />
-
**[[2kbf]] - yDBP5 C terminal – NMR<BR />
+
**[[2kbe]] – yDbp5 N terminal – NMR<BR />
-
**[[3gfp]] - yDBP5 C-terminal<BR />
+
**[[2kbf]] - yDbp5 C terminal – NMR<BR />
-
**[[2hjv]] – BsDBPA domain 2 – ''Bacillus subtilis''<BR />
+
**[[3gfp]] - yDbp5 C-terminal<BR />
-
**[[2g0c]] - BsDBPA RNA-binding domain<br />
+
**[[2hjv]] – BsDbpA domain 2 – ''Bacillus subtilis''<BR />
-
**[[3eaq]], [[3ear]], [[3eas]] – TtHera residues 215-426 - ''Thermus thermophilus''<br />
+
**[[2g0c]] - BsDbpA RNA-binding domain<br />
-
**[[3i31]] - TtHera residues 431-517<br />
+
**[[3eaq]], [[3ear]], [[3eas]] – TtHera residues 215-426 <br />
 +
**[[3i31]], [[4i68]], [[5mao]] - TtHera RRM residues 431-517<br />
 +
**[[4i69]] - TtHera RRM (mutant)<br />
**[[3i32]] - TtHera residues 218-517<br />
**[[3i32]] - TtHera residues 218-517<br />
**[[3nej]] - TtHera N terminal (mutant)<br />
**[[3nej]] - TtHera N terminal (mutant)<br />
 +
**[[4kbf]], [[4kbg]] - TtHera core 8-372<br />
**[[5ivl]] – GsDB CSHA - ''Geobacillus stearothermophilus''<br />
**[[5ivl]] – GsDB CSHA - ''Geobacillus stearothermophilus''<br />
-
**[[5b88]] - EcDBP RRM-like domain - NMR<br />
+
**[[5b88]] - EcDbp RRM-like domain - NMR<br />
-
**[[5gju]] - EcDBP residues 6-210<br />
+
**[[5gju]] - EcDbp residues 6-210<br />
-
**[[5gi4]] - EcDBP residues 218-445<br />
+
**[[5gi4]] - EcDbp residues 218-445<br />
 +
**[[7bbb]] - EcDbpA residues 218-445 - NMR<br />
**[[6aib]] – SaDB CSHA N-terminal – ''Staphylococcus aureus''<br />
**[[6aib]] – SaDB CSHA N-terminal – ''Staphylococcus aureus''<br />
*''Dead box ATP-dependent RNA helicase complexes''
*''Dead box ATP-dependent RNA helicase complexes''
-
**[[3fmo]], [[3fhc]] – hDBP5 + Nup214<BR />
+
**[[3fmo]], [[3fhc]] – hDbp5 + Nup214<BR />
-
**[[3fht]] – hDBP5 + AMPPNP + RNA<BR />
+
**[[3fht]] – hDbp5 + AMPPNP + RNA<BR />
**[[6cz5]] - hDDX3X residues 132-607 + AMP<br />
**[[6cz5]] - hDDX3X residues 132-607 + AMP<br />
-
**[[6o5f]] - hDDX3X + RNA<br />
+
**[[6o5f]], [[7liu]] - hDDX3X + RNA<br />
 +
**[[5e7m]], [[5e7j]] – hDDX3X catalytic domain + nucleotide<br />
 +
**[[3fe2]] – hDDX5 + ADP<br />
 +
**[[2wax]], [[2way]], [[6f9s]] – hDDX6 C terminal + peptide<br />
 +
**[[2pl3]] – hDDX10 DEAD domain + ADP<br />
 +
**[[6uv1]], [[6uv2]], [[6uv3]], [[6uv4]] – hDDX17 core domain + RNA<br />
**[[6b4k]] – hDDX19B residues 54-479 + ANP<br />
**[[6b4k]] – hDDX19B residues 54-479 + ANP<br />
**[[6b4j]], [[6b4i]] – hDDX19B residues 54-479 + GLE1 + Nup42 + ANP<br />
**[[6b4j]], [[6b4i]] – hDDX19B residues 54-479 + GLE1 + Nup42 + ANP<br />
Line 154: Line 215:
**[[3g0h]] – hDDX19B residues 54-275 + ATP analog + RNA<BR />
**[[3g0h]] – hDDX19B residues 54-275 + ATP analog + RNA<BR />
**[[3ews]] - hDDX19B residues 54-275 + ADP<BR />
**[[3ews]] - hDDX19B residues 54-275 + ADP<BR />
-
**[[5e7m]], [[5e7j]] – hDDX3X catalytic domain + nucleotide<br />
+
**[[3b7g]] – hDDX20 + AMPPNP<br />
-
**[[3dkp]] – hDDX52 domain I + ADP<BR />
+
**[[6l5m]] – hDDX21 + AMP<br />
-
**[[2wax]], [[2way]] – hDDX6 C terminal + EDC3-FDF peptide<BR />
+
**[[6l5n]] – hDDX21 + RNA<br />
 +
**[[7oi6]] – hDDX28 in 39S mitoribosome – Cryo EM<br />
 +
**[[7apk]] – hDDX39B in transcription-export complex – Cryo EM<br />
 +
**[[7evn]], [[7evo]] – hDDX42 in spliceosome – Cryo EM<br />
 +
**[[8hk1]] – hDDX42 in pre-17S U2 – Cryo EM<br />
 +
**[[7q3l]] – hDDX46 in pre-17S U2 – Cryo EM<br />
 +
**[[3ber]] – hDDX47 + AMP<br />
 +
**[[6icz]] – hDDX48 in spliceosome – Cryo EM<br />
**[[2j0s]], [[2j0q]], [[2hyi]] – hDDX48 + protein mago nashi homolog + RNA-binding protein 8A + protein CASC3 + RNA<BR />
**[[2j0s]], [[2j0q]], [[2hyi]] – hDDX48 + protein mago nashi homolog + RNA-binding protein 8A + protein CASC3 + RNA<BR />
**[[2j0u]] - hDDX48 + protein CASC3<BR />
**[[2j0u]] - hDDX48 + protein CASC3<BR />
 +
**[[3dkp]] – hDDX52 domain I + ADP<br />
 +
**[[3og8]] – hDDX58 C terminal + RNA<br />
**[[2db3]] – DmVASA residues 200-623 + RNA – ''Drosophila melanogaster''<br />
**[[2db3]] – DmVASA residues 200-623 + RNA – ''Drosophila melanogaster''<br />
**[[5nt7]] – DmVASA RecA-like domain + maternal effect protein<br />
**[[5nt7]] – DmVASA RecA-like domain + maternal effect protein<br />
 +
**[[4d25]] – VASA (mutant) + RNA + AMPPNP - bee<br />
**[[3rrm]] – yDBP5 residues 91-482 (mutant) + GLE1 + NUP159 + ADP + IP6<BR />
**[[3rrm]] – yDBP5 residues 91-482 (mutant) + GLE1 + NUP159 + ADP + IP6<BR />
-
**[[3rrn]] - yDBP5 residues 91-482 (mutant) + GLE1 + IP6<BR />
+
**[[3rrn]] - yDbp5 residues 91-482 (mutant) + GLE1 + IP6<BR />
-
**[[5elx]] - yDBP5 residues 91-482 + RNA<br />
+
**[[5elx]] - yDbp5 residues 91-482 + RNA<br />
-
**[[3pew]], [[3pey]] - yDBP5 residues 91-482 (mutant) + ADP + BeF3 + RNA<BR />
+
**[[3pew]], [[3pey]] - yDbp5 residues 91-482 (mutant) + ADP + BeF3 + RNA<BR />
-
**[[3peu]], [[3pev]] - yDBP5 C-terminal (mutant) + GLE1 + IP6<BR />
+
**[[3peu]], [[3pev]] - yDbp5 C-terminal (mutant) + GLE1 + IP6<BR />
**[[3i5x]], [[3i5y]] – yMSS116 + AMPPNP + RNA<BR />
**[[3i5x]], [[3i5y]] – yMSS116 + AMPPNP + RNA<BR />
**[[3sqw]], [[3sqx]] - yMSS116 + AMPPNP + RNA<BR />
**[[3sqw]], [[3sqx]] - yMSS116 + AMPPNP + RNA<BR />
Line 171: Line 242:
**[[3i62]] - yMSS116 + ADP + AlF4 + RNA<BR />
**[[3i62]] - yMSS116 + ADP + AlF4 + RNA<BR />
**[[4tyn]] - yMSS116 + ADP + DNA<br />
**[[4tyn]] - yMSS116 + ADP + DNA<br />
 +
**[[4db2]] - yMSS116 domain 2 + RNA<br />
 +
**[[4db4]] - yMSS116 domain 2 + RNA + DNA<br />
 +
**[[8arp]] – yDbp2 + ADP<br />
**[[2xau]], [[3kx2]], [[5jpt]] – yPrp43 + nucleotide<BR />
**[[2xau]], [[3kx2]], [[5jpt]] – yPrp43 + nucleotide<BR />
**[[5i8q]] - yPrp43 + ADPNP + RNA<br />
**[[5i8q]] - yPrp43 + ADPNP + RNA<br />
Line 177: Line 251:
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3jrv]] – DDX3X + protein K7 – Vaccinia virus<BR />
**[[3nbf]] - TtHera N terminal (mutant) + 8-oxo-ADP<br />
**[[3nbf]] - TtHera N terminal (mutant) + 8-oxo-ADP<br />
-
**[[3moj]] - BsDBPA RNA-binding domain + RNA<br />
+
**[[4i67]] - TtHera RRM + RNA<br />
 +
**[[3moj]] - BsDbpA RNA-binding domain + RNA<br />
 +
**[[7pli]], [[7pmm]], [[7pmq]] - EcDbpA + RNA<br />
**[[6aic]] – SaDB CSHA N-terminal + AMP <br />
**[[6aic]] – SaDB CSHA N-terminal + AMP <br />
 +
**[[7ase]], [[7ask]] – DDX60 in 43S preinitiation complex complex – Trypanosoma cruzi - Cryo EM<br />
* DEAH box RNA helicase
* DEAH box RNA helicase
Line 187: Line 264:
**[[6hyt]] – hDHX8 helicase domain + ADP<br />
**[[6hyt]] – hDHX8 helicase domain + ADP<br />
**[[6hyu]] – hDHX8 helicase domain + RNA<br />
**[[6hyu]] – hDHX8 helicase domain + RNA<br />
 +
**[[5mqf]], [[7w59]] – hDHX8 in pre-C*-I complex – Cryo EM<br />
**[[3llm]] – hDHX9<br />
**[[3llm]] – hDHX9<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
**[[5xdr]] – hDHX15 residues 110-795 (mutant)<br />
 +
**[[8ejm]] – hDHX15 residues 110-795 + SUGP1<br />
**[[6sh6]], [[6sh7]] – hDHX15 + Nfkb-repressing factor + ADP<br />
**[[6sh6]], [[6sh7]] – hDHX15 + Nfkb-repressing factor + ADP<br />
 +
**[[5z58]] – hDHX16 in spliceosome – Cryo EM<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
**[[2n16]] – hDHX36 G-quadruplex domain - NMR<br />
 +
**[[7a5p]] – hDHX38 in spliceosome – Cryo EM<br />
**[[2rqa]] – hDHX58 C terminal – NMR<br />
**[[2rqa]] – hDHX58 C terminal – NMR<br />
**[[3vyx]], [[3vyy]] – hDHX9 RNA-binding domain + RNA<br />
**[[3vyx]], [[3vyy]] – hDHX9 RNA-binding domain + RNA<br />
 +
**[[6q6r]] – hDHX36 G-quadruplex domain + DNA <br />
**[[2n21]] – hDHX36 G-quadruplex domain + DNA - NMR<br />
**[[2n21]] – hDHX36 G-quadruplex domain + DNA - NMR<br />
**[[5e3h]] - hDHX58 residues 232-925 + RNA<br />
**[[5e3h]] - hDHX58 residues 232-925 + RNA<br />
**[[3eqt]]- hDHX58 residues 541-678 + RNA<br />
**[[3eqt]]- hDHX58 residues 541-678 + RNA<br />
-
**[[5vha]] – bDHX36 residues 150-1010 - bovine<br />
+
**[[5vha]] – bDHX36 residues 150-1010 <br />
**[[5vhc]], [[5vhd]] – bDHX36 residues 150-1010 + ADP<br />
**[[5vhc]], [[5vhd]] – bDHX36 residues 150-1010 + ADP<br />
**[[5vhe]] – bDHX36 residues 56-1010 + DNA<br />
**[[5vhe]] – bDHX36 residues 56-1010 + DNA<br />
**[[2rs6]], [[2rs7]] – mDHX9 RNA-binding domain – NMR<br />
**[[2rs6]], [[2rs7]] – mDHX9 RNA-binding domain – NMR<br />
-
**[[6heg]], [[6eud]] – EcHRPB<br />
+
**[[6up2]] – mDHX36 <br />
 +
**[[6up4]] – mDHX36 + ADP <br />
 +
**[[6up3]] – mDHX36 + ANP <br />
 +
**[[5n6e]], [[5n8r]], [[5n8s]], [[5n8u]], [[5n8z]], [[5n90]], [[5n94]], [[5n98]], [[5n9a]], [[5n9f]] – DmDHX36 + DNA <br />
 +
**[[7dcq]] – yPrp2 – Cryo EM<br />
 +
**[[7dcr]] – yPrp2 + Spp2 – Cryo EM<br />
 +
**[[7dd3]] – yPrp2 + Spp2 + RNA – Cryo EM<br />
 +
**[[7dcp]] – yPrp2 + Spp2 + ADP – Cryo EM<br />
 +
**[[7d4i]] – yDhr1 in 90S ribosome – Cryo EM<br />
 +
**[[6h57]] – yDhr1 <br />
 +
**[[6zwx]] – EcHrpA<br />
 +
**[[7akp]] – EcHrpA (mutant)<br />
 +
**[[6zww]] – EcHrpA + RNA<br />
 +
**[[6heg]], [[6eud]] – EcHrpB + ADP<br />
*ATP-dependent RNA helicase
*ATP-dependent RNA helicase
Line 212: Line 307:
**[[6c90]] - hDOB1 residues 70-600 + ZCCHC8<br />
**[[6c90]] - hDOB1 residues 70-600 + ZCCHC8<br />
**[[6d6r]], [[6d6q]] - hDOB1 in exosome + RNA – Cryo EM<br />
**[[6d6r]], [[6d6q]] - hDOB1 in exosome + RNA – Cryo EM<br />
 +
**[[7z4y]] – hMTR4 in exosome – Cryo EM<br />
 +
**[[5z3g]], [[6c0f]], [[6cb1]], [[6em3]], [[6em4]], [[6em5]], [[7r6q]], [[7r72]], [[8e5t]], [[8etg]], [[8eti]], [[8euy]], [[8ev3]] - yHas1 in 60S ribosome biogenesis intermediate + RNA – Cryo EM<br />
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xzl]] – yNAM7 CH and helicase domains + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
**[[2xgj]] – yDOB1 residues 81-1073 + RNA<BR />
Line 219: Line 316:
**[[5suq]] – ySUB2 + TEX1 + THO2 <br />
**[[5suq]] – ySUB2 + TEX1 + THO2 <br />
**[[5sup]] – ySUB2 + YRA1 + RNA <br />
**[[5sup]] – ySUB2 + YRA1 + RNA <br />
 +
**[[7apx]], [[7luv]], [[7v2y]] – ySUB2 in THO complex – Cryo EM <br />
**[[2vso]], [[2vsx]] – yEIF4A + initiation factor 4F middle domain<BR />
**[[2vso]], [[2vsx]] – yEIF4A + initiation factor 4F middle domain<BR />
**[[2g9n]] - hEIF4A dead domain
**[[2g9n]] - hEIF4A dead domain
Line 224: Line 322:
*Viral ATP-dependent RNA helicase NS3
*Viral ATP-dependent RNA helicase NS3
-
**[[3o8b]], [[3o8d]], [[1cu1]], [[8ohm]], [[1hei]], [[4a92]], [[3rvb]] – HvHel NS3 residues 1186-1658 – Hepatitis C virus<BR />
+
**[[3o8b]], [[3o8d]], [[1cu1]], [[8ohm]], [[1hei]], [[4a92]], [[3rvb]], [[5wdx]] – HvHel NS3 residues 1186-1658 – Hepatitis C virus<BR />
**[[1onb]], [[1jr6]] - HvHel NS3 arginine-rich domain residues 1353-1507 – NMR<BR />
**[[1onb]], [[1jr6]] - HvHel NS3 arginine-rich domain residues 1353-1507 – NMR<BR />
**[[2jlq]], [[2bhr]], [[2bmf]], [[2whx]], [[2wzq]] – DvHel NS3 residues 1646-2092 – Dengue virus<BR />
**[[2jlq]], [[2bhr]], [[2bmf]], [[2whx]], [[2wzq]] – DvHel NS3 residues 1646-2092 – Dengue virus<BR />
Line 231: Line 329:
**[[2v8o]], [[2wv9]] - Hel NS3 helicase domain – Murray valley encephalitis virus<BR />
**[[2v8o]], [[2wv9]] - Hel NS3 helicase domain – Murray valley encephalitis virus<BR />
**[[2qeq]] - Hel NS3 residues 1691-2124 – Kunjin virus<BR />
**[[2qeq]] - Hel NS3 residues 1691-2124 – Kunjin virus<BR />
-
**[[5txg]], [[5jmt]], [[5vi7]], [[5jps]], [[6mh3]] - ZvHel NS3 helicase domain – Zika virus<br />
+
**[[5txg]], [[5jmt]], [[5rhy]], [[5vi7]], [[5jps]], [[6adw]], [[6mh3]] - ZvHel NS3 helicase domain 1674-2119 – Zika virus<br />
**[[5k8u]], [[5k8l]], [[5k8i]], [[5jwh]], [[5jrz]] - ZvHel NS3 residues 164-621<br />
**[[5k8u]], [[5k8l]], [[5k8i]], [[5jwh]], [[5jrz]] - ZvHel NS3 residues 164-621<br />
**[[5x8y]] - ZvHel NS1 residues 168-352<br />
**[[5x8y]] - ZvHel NS1 residues 168-352<br />
Line 237: Line 335:
**[[2v6j]] - KvHel helicase domain (mutant)<br />
**[[2v6j]] - KvHel helicase domain (mutant)<br />
**[[5wso]], [[5gvu]] - Hel NS3 residues 1939-2414 – bovine viral diarrhea virus<br />
**[[5wso]], [[5gvu]] - Hel NS3 residues 1939-2414 – bovine viral diarrhea virus<br />
 +
**[[1yks]], [[5ffm]] - Hel NS3 helicase domain – yellow fever virus<br />
 +
**[[7wd4]] - Hel NS3 helicase domain – ilheus virus<br />
 +
**[[4cbg]], [[4cbh]], [[4cbi]], [[4cbl]], [[4cbm]] - Hel NS3 helicase domain – pestivirus<br />
 +
**[[7nno]], [[7oj4]] - TbevHel NS3 helicase domain – Tick-bourne encephalitis virus<br />
*''Viral ATP-dependent RNA helicase NS3 complexes''
*''Viral ATP-dependent RNA helicase NS3 complexes''
**[[3o8c]], [[3o8r]], [[3kqh]], [[3kqk]], [[3kql]], [[3kqn]], [[3kqu]], [[1a1v]] - HvHel NS3 + RNA<BR />
**[[3o8c]], [[3o8r]], [[3kqh]], [[3kqk]], [[3kql]], [[3kqn]], [[3kqu]], [[1a1v]] - HvHel NS3 + RNA<BR />
 +
**[[2f55]] - HvHel NS3 + DNA<br />
**[[2f9v]] - HvHel NS3 protease domain + polyprotein<BR />
**[[2f9v]] - HvHel NS3 protease domain + polyprotein<BR />
**[[2a4g]], [[1rtl]], [[1w3c]], [[1dxp]] - HvHel NS3 protease domain + NS4A peptide<BR />
**[[2a4g]], [[1rtl]], [[1w3c]], [[1dxp]] - HvHel NS3 protease domain + NS4A peptide<BR />
 +
**[[2zjo]], [[4ok5]], [[4oks]], [[4wxp]], [[4wxr]] - HvHel NS3 + inhibitor<br />
 +
**[[5e4f]] - HvHel NS3 + ADP<br />
**[[2a4q]], [[2a4r]], [[2f9u]], [[2fm2]], [[1dy8]], [[1dy9]] - HvHel NS3 protease domain + NS4A peptide + inhibitor<BR />
**[[2a4q]], [[2a4r]], [[2f9u]], [[2fm2]], [[1dy8]], [[1dy9]] - HvHel NS3 protease domain + NS4A peptide + inhibitor<BR />
-
**[[2jlr]] - DvHel NS3 residues 1646-2092 + AMPPNP<BR />
+
**[[2jlr]] - DvHel NS3 helicase domain + AMPPNP<BR />
-
**[[2jls]] - DvHel NS3 residues 1646-2092 + ADP<BR />
+
**[[2jls]] - DvHel NS3 helicase domain + ADP<BR />
-
**[[2jlu]], [[2jlw]], [[5xc6]] - DvHel NS3 residues 1646-2092 + RNA<BR />
+
**[[2jlu]], [[2jlw]], [[5xc6]] - DvHel NS3 helicase domain + RNA<BR />
-
**[[2jlv]] - DvHel NS3 residues 1646-2092 + AMPPNP + RNA<BR />
+
**[[2jlv]] - DvHel NS3 helicase domain + AMPPNP + RNA<BR />
-
**[[2jlx]], [[2jly]], [[2jlz]] - DvHel NS3 residues 1646-2092 + ADP + RNA<BR />
+
**[[2jlx]], [[2jly]], [[2jlz]] - DvHel NS3 helicase domain + ADP + RNA<BR />
-
**[[2vbc]] - DvHel NS3 residues 1475-2092 + NS2A peptide<br />
+
**[[2vbc]] - DvHel NS3 residues helicase domain + NS2A peptide<br />
**[[5k8t]] - ZvHel NS3 residues 164-621 + GTP<br />
**[[5k8t]] - ZvHel NS3 residues 164-621 + GTP<br />
-
**[[5gjc]] - ZvHel NS3 residues 1676-2119 + ATP<br />
+
**[[5gjc]] - ZvHel NS3 helicase domain + ATP<br />
-
**[[5gjb]] - ZvHel NS3 residues 1676-2119 + RNA<br />
+
**[[5gjb]] - ZvHel NS3 helicase domain + RNA<br />
-
**[[5y4z]] - ZvHel NS3 residues 1676-2119 + AMPPNP<br />
+
**[[5y4z]] - ZvHel NS3 helicase domain + AMPPNP<br />
 +
**[[5rhg]], ]]5rhh]], [[5rhi]], [[5rhj]], [[5rhk]], [[5rhl]], [[5rhm]], [[5rho]], [[5rhp]], [[5rhq]], [[5rhr]], [[5rhs]], [[5rht]], [[5rhu]], [[5rhv]], [[5rhw]], [[5rhx]] - ZvHel NS3 helicase domain + inhibitor<br />
 +
**[[5y6m]], [[5y6n]], [[6adx]], [[6ady]], [[6rwz]], [[6s0j]] - ZvHel NS3 helicase domain + ADP<br />
 +
**[[7blv]], [[7nxu]] - TbevHel NS3 helicase domain + ADP <br />
 +
**[[7bm0]] - TbevHel NS3 helicase domain + AMPPNP <br />
 +
**[[6jim]] - Hel NS3 helicase domain + RNA – chikungunya virus<br />
*ATP-dependent RNA helicase SUV3
*ATP-dependent RNA helicase SUV3
-
**[[3rc3]] – hSUV3 residues 47-722<BR />
+
**[[3rc3]], [[7w1r]] – hSUV3 residues 47-722<BR />
**[[3og8]] – hDDX58 C terminal + RNA<BR />
**[[3og8]] – hDDX58 C terminal + RNA<BR />
**[[3rc8]] - hSUV3 residues 47-722 + RNA<BR />
**[[3rc8]] - hSUV3 residues 47-722 + RNA<BR />
Line 267: Line 377:
**[[3vyx]], [[3vyy]] - hHel A RNA-binding domain + RNA<br />
**[[3vyx]], [[3vyy]] - hHel A RNA-binding domain + RNA<br />
**[[1whq]], [[2rs6]], [[2rs7]] – Hel A RNA-binding domain – mouse - NMR<BR />
**[[1whq]], [[2rs6]], [[2rs7]] – Hel A RNA-binding domain – mouse - NMR<BR />
 +
 +
*ATP-dependent RNA helicase Rep
 +
 +
**[[7lar]], [[7las]] – Rep + DNA + ADP – Porcine circovirus – Cryo EM<br />
*ATP-dependent RNA helicase Repa
*ATP-dependent RNA helicase Repa
Line 286: Line 400:
**[[4bru]] – yDhh1 (mutant) + EDC3<br />
**[[4bru]] – yDhh1 (mutant) + EDC3<br />
**[[4brw]] – yDhh1 (mutant) + PAT1<br />
**[[4brw]] – yDhh1 (mutant) + PAT1<br />
 +
**[[1s2m]] – yDhh1p<br />
*Werner syndrome ATP-dependent DNA helicase
*Werner syndrome ATP-dependent DNA helicase
Line 305: Line 420:
**[[5lb5]], [[5lb3]] – hQ5 + ADP<br />
**[[5lb5]], [[5lb3]] – hQ5 + ADP<br />
**[[5lba]] – hQ5 + urea derivative<br />
**[[5lba]] – hQ5 + urea derivative<br />
 +
**[[7zml]], [[7zmm]], [[7zmn]], [[7zmp]], [[7zmq]], [[7zmt]], [[7zmv]] – hQ5 + nanobody<br />
*ATP-dependent DNA helicase RecG
*ATP-dependent DNA helicase RecG
Line 327: Line 443:
**[[2ztc]], [[2ztd]], [[2zte]], [[2h5x]] – MtRuvA – ''Mycobacterium tuberculosis''<BR />
**[[2ztc]], [[2ztd]], [[2zte]], [[2h5x]] – MtRuvA – ''Mycobacterium tuberculosis''<BR />
-
**[[1bvs]] - RuvA – ''Mycobacterium leprae''<BR />
+
**[[7oa5]] - MlRuvA – ''Mycobacterium leprae''<BR />
 +
**[[7oa5]] - MlRuvA + DNA<br />
**[[1cuk]], [[1hjp]] – EcRuvA<br />
**[[1cuk]], [[1hjp]] – EcRuvA<br />
**[[1d8l]] – EcRuvA N terminal<BR />
**[[1d8l]] – EcRuvA N terminal<BR />
Line 336: Line 453:
**[[1in5]], [[1in6]], [[1in7]], [[1in8]], [[1j7k]] – TmRuvB (mutant)<br />
**[[1in5]], [[1in6]], [[1in7]], [[1in8]], [[1j7k]] – TmRuvB (mutant)<br />
**[[3pfi]] – RuvB + ADP – ''Campylobacter jejuni''<br />
**[[3pfi]] – RuvB + ADP – ''Campylobacter jejuni''<br />
-
**[[6blb]] - PaRuvB + ADP - ''Pseudomonas aeruginosa''<br />
+
**[[6blb]], [[7x5b]] - PaRuvB + ADP - ''Pseudomonas aeruginosa''<br />
 +
**[[7x5a]], [[7x7p]], [[7x7q]] - PaRuvB in Holliday junciton – Cryo EM<br />
 +
**[[7pbl]], [[7pbm]], [[7pbn]], [[7pbo]], [[7pbp]], [[7pbq]], [[7pbr]], [[7pbs]], [[7pbt]], [[7pbu]] – RuvA + RuvB + DNA – Streptococcus thermophiles – Cryo EM<br />
*ATP-dependent DNA helicase RuvB-like
*ATP-dependent DNA helicase RuvB-like
Line 370: Line 489:
**[[2d7e]] – EcPriA DNA-binding domain<BR />
**[[2d7e]] – EcPriA DNA-binding domain<BR />
-
**[[2d7g]], [[2d7h]], [[2dwl]], [[2dwm]], [[2dwn]] – EcPriA N terminal + polynucleotide
+
**[[2d7g]], [[2d7h]], [[2dwl]], [[2dwm]], [[2dwn]] – EcPriA N terminal + polynucleotide<br />
 +
**[[6dgd]] – KpPriA + DNA – ''Klebsiella pneumoniae''<br />
 +
**[[4nl4]] – KpPriA + ADP<br />
 +
**[[4nl8]] – KpPriA + peptide<br />
*ATP-dependent DNA helicase PcrA
*ATP-dependent DNA helicase PcrA
Line 382: Line 504:
*DnaB helicase or replicative DNA helicase
*DnaB helicase or replicative DNA helicase
-
**[[3gxv]] – HpDnaB – ''Helicobacter pylori''<BR />
+
**[[3gxv]], [[4zc0]] – HpDnaB – ''Helicobacter pylori''<BR />
**[[4a1f]] – HpDnaB C terminal<br />
**[[4a1f]] – HpDnaB C terminal<br />
**[[2r6d]] – BsDnaB – ''Bacillus stearothermophilus''<BR />
**[[2r6d]] – BsDnaB – ''Bacillus stearothermophilus''<BR />
Line 393: Line 515:
**[[6frg]], [[6fre]] – SyDnaB (mutant) <br />
**[[6frg]], [[6fre]] – SyDnaB (mutant) <br />
**[[6bbm]] – EcDnaB + replication protein P – Cryo EM<br />
**[[6bbm]] – EcDnaB + replication protein P – Cryo EM<br />
 +
**[[7t21]] – EcDnaB + DNA + ADP – Cryo EM<br />
 +
**[[7t22]], [[7t23]] – EcDnaB (mutant) + DNA primase + DNA + ADP – Cryo EM<br />
**[[1b79]] - EcDnaB N terminal<BR />
**[[1b79]] - EcDnaB N terminal<BR />
**[[1jwe]] - EcDnaB N terminal - NMR<BR />
**[[1jwe]] - EcDnaB N terminal - NMR<BR />
 +
**[[6kza]] - EcDnaB C terminal + DnaC<br />
 +
**[[7t20]] - EcDnaB + DNA + AMPPNP<br />
 +
**[[4esv]] – BsDnaB + DNA<br />
 +
**[[4m4w]] – BsDnaB in primosome <br />
**[[2r6c]], [[2r6a]] – BsDnaB + DnaG helicase-binding domain<br />
**[[2r6c]], [[2r6a]] – BsDnaB + DnaG helicase-binding domain<br />
**[[6bs8]], [[6own]] – MsDnaB 238-376<br />
**[[6bs8]], [[6own]] – MsDnaB 238-376<br />
**[[6rix]], [[6riy]] – DnaB (mutant) – ''Mycobacterium chimaera''<br />
**[[6rix]], [[6riy]] – DnaB (mutant) – ''Mycobacterium chimaera''<br />
 +
**[[6own]], [[6bs8]] – MsDnaB 238-376<br />
 +
**[[7qxm]] – VcDnaB – ''Vibrio cholerae''<br />
 +
**[[6t66]] – VcDnaB + GDP <br />
 +
**[[8a3v]] – VcDnaB + DCIA<br />
 +
**[[4nmn]] – AaDnaB + ADP – ''Aquifex aeolicus''<br />
*DnaC helicase
*DnaC helicase
Line 403: Line 536:
**[[2vyf]]– GkDnaC – ''Geobacillus kaustophilus''<br />
**[[2vyf]]– GkDnaC – ''Geobacillus kaustophilus''<br />
**[[2vye]] – GkDnaC + DNA <br />
**[[2vye]] – GkDnaC + DNA <br />
-
**[[3ec2]] – AaDnaC – ''Aquifex aeolicus''<br />
+
**[[3ec2]] – AaDnaC <br />
**[[3ecc]] – AaDnaC + ADP<br />
**[[3ecc]] – AaDnaC + ADP<br />
-
**[[6qel]] – EcDnaC + replicative DNA Hel <br />
+
**[[6qel]] – EcDnaC + replicative DNA Hel - Cryo EM<br />
-
**[[6qem]] – EcDnaC + replicative DNA Hel + DNA<br />
+
**[[6qem]] – EcDnaC + replicative DNA Hel + DNA - Cryo EM<br />
*Helicase BLM
*Helicase BLM
-
**[[5lup]] – hBLM DHBN domain <br />
+
**[[7auc]] – hBLM 636-1298<br />
 +
**[[7aud]] – hBLM 636-1298 + DNA<br />
 +
**[[5lup]], [[5mk5]] – hBLM DHBN domain 362-414<br />
 +
**[[2mh9]], [[3we2]], [[3we3]] – hBLM RQC domain 1068-1209<br />
 +
**[[2kv2]] – hBLM HRDC domain 1210-1294 - NMR<br />
**[[5lut]] – BLM DHBN domain - chicken<br />
**[[5lut]] – BLM DHBN domain - chicken<br />
**[[5lus]] – BLM DHBN domain - pelican<br />
**[[5lus]] – BLM DHBN domain - pelican<br />
Line 417: Line 554:
**[[4w7s]] – yCa8<br />
**[[4w7s]] – yCa8<br />
 +
**[[5dtu]] – CtPrp28 + ADP<br />
-
*Helicase NSP
+
*Helicase NSP see [[Nonstructural protein]]
-
 
+
-
**[[6jim]] – NSP2 + RNA – Chicungunya virus<br />
+
-
**[[2hwk]] – NSP2 – Venzuelan equine encephalitis virus<br />
+
-
**[[6jyt]] – NSP13 – Human SARS-COV virus<br />
+
*Helicase SEN1
*Helicase SEN1
**[[5mzn]], [[6i59]] – ySEN1<br />
**[[5mzn]], [[6i59]] – ySEN1<br />
 +
**[[6o3w]], [[6o3x]], [[6o3y]] – ySEN1 + Nrd1<br />
*Helicase DING
*Helicase DING
Line 434: Line 569:
*Helicase SNF2
*Helicase SNF2
 +
**[[5x0x]], [[5x0y]], [[5z3o]], [[5z3u]], [[5z3v]], [[6iy2]], [[6iy3]], [[6uxw]], [[7c4j]], [[7egm]], [[7egp]] – ySNF2 in nucleosome – Cryo EM<br />
**[[1z5z]] – SsSNF2 C terminal – ''Sulfolobus solfataricus''<br />
**[[1z5z]] – SsSNF2 C terminal – ''Sulfolobus solfataricus''<br />
**[[1z63]] - SsSNF2 ATPase core + DNA<br />
**[[1z63]] - SsSNF2 ATPase core + DNA<br />
Line 440: Line 576:
*Helicase SKI2
*Helicase SKI2
 +
**[[7qdy]], [[7qdz]], [[7qe0]] – hSKI2W + TPR repeat protein + SKI8 + RNA – Cryo EM<br />
 +
**[[7qdr]], [[7qds]] – hSKI2W + TPR repeat protein + SKI8 – Cryo EM<br />
 +
**[[4buj]] – ySKI2 + superkiller protein + SKI8 <br />
**[[4a4k]] – ySKI2 insertion domain<br />
**[[4a4k]] – ySKI2 insertion domain<br />
**[[4a4z]] – ySKI2 + AMPPNP<br />
**[[4a4z]] – ySKI2 + AMPPNP<br />
Line 456: Line 595:
**[[5ivw]] - hXPD + XPB + TFIIH ubunits 2,3,4,5 + SCP-X + SCP-Ybr />
**[[5ivw]] - hXPD + XPB + TFIIH ubunits 2,3,4,5 + SCP-X + SCP-Ybr />
-
*Pre-mRNA-splicing Helicase
+
*Pre-mRNA-splicing Helicase or Brr2 or ski2-like
 +
**[[4f92]] – hBrr2 402-2125<br />
 +
**[[4f91]] – hBrr2 helicase region 394-213<br />
 +
**[[6s8o]] – hBrr2 helicase region (mutant)<br />
 +
**[[4f93]] – hBrr2 helicase region (mutant) + ATP + ADP<br />
 +
**[[8bch]] – hBrr2 helicase region + sulfaguanidine<br />
 +
**[[5urj]], [[5urk]], [[5urm]] – hBrr2 helicase region + inhibitor<br />
 +
**[[4kit]], [[6s8q]], [[6s9i]], [[8bc9]] – hBrr2 helicase region + pre-mRNA-splicing factor 8<br />
 +
**[[8bc8]], [[8bcb]], [[8bcc]], [[8bcd]], [[8bcf]] , [[8bcg]] – hBrr2 helicase region + pre-mRNA-splicing factor 8 + inhibitor<br />
 +
**[[7os2]] – hBrr2 helicase region + pre-mRNA-splicing factor 8 + telomere length and silencing protein – Cryo EM<br />
 +
**[[7os1]] – hBrr2 helicase region + WBP-4 – Cryo EM<br />
 +
**[[7px3]] – hBrr2 helicase region + pre-mRNA-splicing factor 8 + TSSC4 – Cryo EM<br />
 +
**[[3jcm]], [[3jcr]], [[5gap]] – hBrr2 helicase region in U4/U6.U5 snRNP complex – Cryo EM<br />
 +
**[[7bdi]], [[7bdj]], [[7bdk]], [[7bdl]] – hBrr2 394-2136 + pre-mRNA-splicing factor 8 + nucleotide<br />
**[[3hib]], [[3im1]], [[3im2]] – yBrr2 2nd SEC63 domain<br />
**[[3hib]], [[3im1]], [[3im2]] – yBrr2 2nd SEC63 domain<br />
**[[4bgd]], [[5m5p]], [[5m52]], [[5dca]] – yBrr2 + pre-mRNA-splicing factor 8<br />
**[[4bgd]], [[5m5p]], [[5m52]], [[5dca]] – yBrr2 + pre-mRNA-splicing factor 8<br />
 +
**[[5gan]], [[5gao]] – yBrr2 in U4/U6.U5 complex – Cryo EM<br />
 +
**[[5lj5]], [[5lqw]] – yBrr2 in spliceosome – Cryo EM<br />
 +
**[[6qws]] – CtBrr2 473-2193<br />
 +
**[[4rvq]] – CtBrr2 PWI-like domain 287-422<br />
 +
**[[6qv4]] – CtBrr2 + ATPgS<br />
 +
**[[6qv3]] – CtBrr2 + ADP<br />
*crispr-associated helicase Cas3
*crispr-associated helicase Cas3
Line 471: Line 629:
**[[5gqh]] – PaCas3 + anti-crispr protein 3 <br />
**[[5gqh]] – PaCas3 + anti-crispr protein 3 <br />
**[[5b7i]] – PaCas3 + ACRF3<br />
**[[5b7i]] – PaCas3 + ACRF3<br />
 +
 +
*Helicase aquarius or intron-binding protein aquarius
 +
 +
**[[4pj3]] – hHA + AMPPNP <br />
 +
**[[6id0]], [[6id1]] – hHA in spliceosome – Cryo EM<br />
 +
**[[3jb9]] – fyHA in spliceosome – Cryo EM<br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of helicase

Updated on 10-May-2023

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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