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5m9o

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Current revision (18:33, 1 November 2023) (edit) (undo)
 
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<StructureSection load='5m9o' size='340' side='right'caption='[[5m9o]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5m9o' size='340' side='right'caption='[[5m9o]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M9O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5m9o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M9O FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SND1, TDRD11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [http://pdbe.org/5m9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [http://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m9o OCA], [https://pdbe.org/5m9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m9o RCSB], [https://www.ebi.ac.uk/pdbsum/5m9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m9o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN]] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
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[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Chan, C]]
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[[Category: Chan C]]
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[[Category: Delft, F von]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Fedorov O]]
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[[Category: Fedorov, O]]
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[[Category: Knapp S]]
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[[Category: Knapp, S]]
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[[Category: La Thangue NB]]
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[[Category: Moehlenbrink, J]]
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[[Category: Moehlenbrink J]]
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[[Category: Nunez-Alonso, G]]
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[[Category: Nunez-Alonso G]]
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[[Category: Structural genomic]]
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[[Category: Savitsky P]]
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[[Category: Savitsky, P]]
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[[Category: Siejka P]]
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[[Category: Siejka, P]]
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[[Category: Sorrell FJ]]
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[[Category: Sorrell, F J]]
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[[Category: Tallant C]]
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[[Category: Tallant, C]]
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[[Category: Von Delft F]]
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[[Category: Thangue, N B.La]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Transcriptional coactivator]]
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Current revision

Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide

PDB ID 5m9o

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