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Insulin-like growth factor

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== Relevance ==
== Relevance ==
Inhibition of IGF I influences colon cancer<ref>PMID:11694656</ref>. IGF I has protective effect in neuropathy<ref>PMID:15832492</ref>.
Inhibition of IGF I influences colon cancer<ref>PMID:11694656</ref>. IGF I has protective effect in neuropathy<ref>PMID:15832492</ref>.
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See also [[Insulin-like growth factor receptor]] and [[Insulin-like growth factor 1]].
</StructureSection>
</StructureSection>
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**[[6ff3]] - hIGF I + neural ectodermal development factor<br />
**[[6ff3]] - hIGF I + neural ectodermal development factor<br />
**[[6pyh]] - hIGF I + mIGFI receptor – Cryo EM<br />
**[[6pyh]] - hIGF I + mIGFI receptor – Cryo EM<br />
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**[[7wrq]] - hIGF I + IGFBP3 + ALS – Cryo EM<br />
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**[[7s0q]] - hIGF I + IGFI receptor + insulin receptor – Cryo EM<br />
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**[[8eyr]] - hIGF I 1-195 + IGFI receptor – Cryo EM<br />
*IGF II residues 25-91
*IGF II residues 25-91
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**[[1igl]], [[5l3l]], [[5l3m]], [[5l3n]] - hIGF II – NMR<BR />
**[[1igl]], [[5l3l]], [[5l3m]], [[5l3n]] - hIGF II – NMR<BR />
**[[3e4z]] – hIGF II + insulin-degrading enzyme<BR />
**[[3e4z]] – hIGF II + insulin-degrading enzyme<BR />
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**[[3kr3]] - hIGF II + antibody<br />
**[[6um2]] - hIGF II + bIGFII receptor – Cryo EM<br />
**[[6um2]] - hIGF II + bIGFII receptor – Cryo EM<br />
**[[6vwg]], [[6vwi]] - hIGF II + IGFI receptor – Cryo EM<br />
**[[6vwg]], [[6vwi]] - hIGF II + IGFI receptor – Cryo EM<br />

Current revision

Structure of insulin-like growth factor I complex with detergent (PDB entry 1gzr)

Drag the structure with the mouse to rotate

3D structures of insulin-like growth factor

Updated on 17-January-2024

References

  1. ↑ Wood AW, Duan C, Bern HA. Insulin-like growth factor signaling in fish. Int Rev Cytol. 2005;243:215-85. PMID:15797461 doi:http://dx.doi.org/10.1016/S0074-7696(05)43004-1
  2. ↑ Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr. 2001 Nov;131(11 Suppl):3109S-20S. PMID:11694656
  3. ↑ Mohamed-Ali V, Pinkney J. Therapeutic potential of insulin-like growth factor-1 in patients with diabetes mellitus. Treat Endocrinol. 2002;1(6):399-410. PMID:15832492

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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