7a2a
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7a2a is ON HOLD Authors: Niggenaber, J., Mueller, M.P., Rauh, D. Description: Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001== | |
| + | <StructureSection load='7a2a' size='340' side='right'caption='[[7a2a]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A2A FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=57N:(2R)-2-(1-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-2-PHENYL-N-(1,3-THIAZOL-2-YL)ACETAMIDE'>57N</scene>, <scene name='pdbligand=7G9:~{N}-[3-[[5-FLUORANYL-2-[[4-(2-METHOXYETHOXY)PHENYL]AMINO]PYRIMIDIN-4-YL]AMINO]PHENYL]PROPANAMIDE'>7G9</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a2a OCA], [https://pdbe.org/7a2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a2a RCSB], [https://www.ebi.ac.uk/pdbsum/7a2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a2a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mueller MP]] |
| - | [[Category: Rauh | + | [[Category: Niggenaber J]] |
| + | [[Category: Rauh D]] | ||
Current revision
Crystal Structure of EGFR-T790M/V948R in Complex with Spebrutinib and EAI001
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